Resumes
Resumes
Monica Foermer Phones & Addresses
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2236 Browning St, Berkeley, CA 94702 (510) 845-9697
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2236 Browning St APT A, Berkeley, CA 94702 (510) 845-9697
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1144 Key Route Blvd, Albany, CA 94706
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Oakland, CA
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73 Alpha St, San Francisco, CA 94134
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Pacifica, CA
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Saint Olaf, IA
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Grand Rapids, MI
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Alameda, CA
Publications
Us Patents
Methods For High Purity Chromatographic Separation Of Proteins Having Egf-Like Binding Domains
View pageUS Patent:
53788168, Jan 3, 1995
Filed:
Dec 16, 1992
Appl. No.:
7/991800
Inventors:
Erno Pungor - Foster City CA
Les Johnson - West Pittsburg CA
Monica R. Foermer - San Francisco CA
Les Johnson - West Pittsburg CA
Monica R. Foermer - San Francisco CA
Assignee:
Berlex Laboratories, Inc. - Cedar Knolls NJ
International Classification:
A61K 3700
US Classification:
530412
Abstract:
Proteins having an epidermal growth factor-like binding region, such as thrombomodulin, may be recovered and purified on a anion exchange resin, such as a polyethyleneimine resin. Conditioned medium containing recombinantly produced protein is applied to the resin under conditions of pH and ionic strength selected to result in specific binding of the protein to the resin. The column is then washed to remove non-bound proteins and bound proteins other than the desired protein to be separated. The desired protein is then eluted from the column and collected in a medium. Further purification, concentration, and other treatment of the protein may be performed by conventional techniques.