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Mohammed Asmal

from Newton, MA
Age ~51
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Also known as:
Mohammad Osmal
Phone and address:
69 Fair Oaks Ave, Newton, MA 02460
(617) 969-0152
Related to:
Paul J Faraci, 78Lisa Whitlock, 55Mary E FaraciDavid DegrangeBethany Degrange, 34Brenda Barrett, 59
Connected to:
John Asmal, 34Daniel R Asman, 29Gustavo Asman, 66Jennifer L Asman, 62Lucas A Asman, 34Raylene Asman, 37Samuel C Asman, 37Zach M Asman, 56Jade Asmann, 41Abdo R Asmar, 51

Mohammed Asmal Phones & Addresses

  • 69 Fair Oaks Ave, Newtonville, MA 02460 (617) 969-0152
  • Newton, MA
  • 111 Perkins St, Jamaica Plain, MA 02130
  • 111 Park St, Boston, MA 02215 (617) 267-7024
  • 60 Haven Ave, New York, NY 10032 (212) 928-9480
  • 4 Larkspur Rd, Needham, MA 02492 (781) 444-7995
  • 715 W 172Nd St APT 36, New York, NY 10032

Work

Company: BRIGHAM & WOMENS HOSPITAL Address: 75 Francis St, Boston, MA 02115 Phones: (617) 732-5500 (617) 731-5453

Education

School / High School: Columbia Univ Coll Of Physicians and Surgeons 1999

Languages

English

Awards

Healthgrades Honor Roll

Ranks

Certificate: Infectious Disease, 2008

Specialities

Infectious Disease Medicine

Professional Records

Medicine Doctors

Mohammed Asmal Photo 1

Dr. Mohammed Asmal, Boston MA - MD (Doctor of Medicine)

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Specialties:
Infectious Disease Medicine
Age:
51
Address:
75 Francis St Suite B, Boston, MA 02115
(617) 732-8881 (Phone), (617) 732-6829 (Fax)

BRIGHAM & WOMENS HOSPITAL
75 Francis St, Boston, MA 02115
(617) 732-5500 (Phone), (617) 731-5453 (Fax)
Certifications:
Infectious Disease, 2008
Internal Medicine, 2007
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
75 Francis St Suite B, Boston, MA 02115

BRIGHAM & WOMENS HOSPITAL
75 Francis St, Boston, MA 02115

Beth Israel Deaconess Medical Center
330 Brookline Avenue, Boston, MA 02215

Brigham and Women's Hospital
75 Francis Street, Boston, MA 02115
Education:
Medical School
Columbia Univ Coll Of Physicians and Surgeons
Graduated: 1999
Medical School
Brigham And Women'S Hospital
Graduated: 1999
Medical School
Massachusetts General Hospital
Graduated: 1999
Mohammed Asmal Photo 2

Mohammed Asmal, Boston MA

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Specialties:
Internal Medicine
Infectious Disease
Work:
Brigham & Women's Hospital
75 Francis St, Boston, MA 02115
Education:
Columbia University (2003)
Mohammed Asmal Photo 3

Mohammed Asmal, Boston MA

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Specialties:
Infectious Disease Specialist
Address:
75 Francis St, Boston, MA 02115
Education:
Columbia University, College of Physicians and Surgeons - Doctor of Medicine
Board certifications:
American Board of Internal Medicine Certification in Internal Medicine
American Board of Internal Medicine Sub-certificate in Infectious Disease (Internal Medicine)

Resumes

Resumes

Mohammed Asmal Photo 4

Entrepreneur In Residence

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Location:
Newtonville, MA
Industry:
Pharmaceuticals
Work:
Orbimed
Entrepreneur In Residence
Bluebird Bio
Vice President, Head of Clinical Research and Development
Bluebird Bio Aug 2015 - Jan 2017
Senior Medical Director and Hemoglobinopathy Program Lead
Vertex Pharmaceuticals Dec 1, 2011 - Aug 2015
Medical Director, Clinical Development
Vertex Pharmaceuticals Dec 2011 - Oct 2013
Associate Medical Director, Clinical Development
Education:
Columbia University 1995 - 2003
Doctor of Medicine, Doctorates, Medicine Columbia University Vagelos College of Physicians and Surgeons 1995 - 2002
Columbia University 1997 - 2002
Doctorates, Doctor of Philosophy, Molecular Biology, Biochemistry, Biology Harvard University 1991 - 1995
Bachelors, Bachelor of Arts, Biology, Biomedical Engineering, Engineering Needham High School
Skills:
Infectious Diseases
Clinical Trials
Immunology
Molecular Biology
Cancer
Clinical Research
Clinical Development
Internal Medicine
Oncology
Virology
Medical Research
Medicine
Biochemistry
Healthcare
Translational Research
Research
Hospitals
Lifesciences
Neuroscience
Cell Biology
Biostatistics
Vaccines
Life Sciences
Cell Culture
Healthcare Information Technology
Treatment
Epidemiology
Medical Education
Public Health
Global Health
Analysis
Teaching
Flow Cytometry
Cancer Research
Western Blotting
Genetics
Biomarkers
Gene Therapy
Orphan Drugs
Interests:
International Medical Relief
Environment
Science and Technology
Disaster and Humanitarian Relief
Human Rights
Health
Languages:
English
Spanish
Mohammed Asmal Photo 5

Infectious Disease Physician And Researcher

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Position:
Post-doctoral Research Fellow at Beth Israel Deaconess Medical Center, Infectious Diseases at Partners Healthcare
Location:
Greater Boston Area
Industry:
Hospital & Health Care
Work:
Beth Israel Deaconess Medical Center since Jun 2007
Post-doctoral Research Fellow
Partners Healthcare since Jun 2006
Infectious Diseases
Brigham and Women's Hospital Jun 2003 - Jun 2006
Internal Medicine Resident
Education:
Columbia University College of Physicians and Surgeons 1995 - 2002
Harvard University 1991 - 1995
BA, Engineering, Biology

Business Records

Name / Title
Company / Classification
Phones & Addresses
Mohammed Asmal
Mohammed Asmal MD,PHD
Internist
75 Francis St, Boston, MA 02115
(617) 525-8281
Mohammed Asmal
Medical Doctor
Stephen J Ferzoco
Medical Doctor's Office · Medical Doctor's Office General Hospital
75 Francis St, Boston, MA 02115

Publications

Us Patents

Compounds Useful As Inhibitors Of Atr Kinase And Combination Therapies Thereof

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US Patent:
20140044802, Feb 13, 2014
Filed:
Apr 5, 2013
Appl. No.:
13/857658
Inventors:
Vertex Pharmaceuticals Incorporated - , US
Philip Michael Reaper - Abingdon, GB
Mohammed Asmal - Newton MA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
A61K 31/497
C07D 241/28
C07D 413/04
A61K 33/24
A61K 45/06
A61K 31/4965
A61K 31/55
US Classification:
424649, 51425506, 51425505, 51421206
Abstract:
The present invention relates to compounds useful as inhibitors of ATR protein kinase and combination therapies thereof. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors.The compounds of this invention have formula I:wherein the variables are as defined herein.

Compounds Useful As Inhibitors Of Atr Kinase And Combination Therapies Thereof

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US Patent:
20220233521, Jul 28, 2022
Filed:
Aug 3, 2021
Appl. No.:
17/444318
Inventors:
- Boston MA, US
Philip Michael Reaper - Abingdon, GB
Mohammed Asmal - Newton MA, US
International Classification:
A61K 31/496
A61K 31/4965
A61K 33/243
A61K 31/497
A61K 31/55
A61K 45/06
C07D 413/04
Abstract:
The present invention relates to compounds useful as inhibitors of ATR protein kinase and combination therapies thereof. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors.The compounds of this invention have formula I:wherein the variables are as defined herein.

Method For Treating Cancer Using A Combination Of Dna Damaging Agents And Atr Inhibitors

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US Patent:
20230106592, Apr 6, 2023
Filed:
Aug 18, 2022
Appl. No.:
17/820773
Inventors:
- Boston MA, US
Peter LITTLEWOOD - Abingdon, GB
Philip Michael REAPER - Abingdon, GB
Mohammed ASMAL - Newton MA, US
Scott Zachary FIELDS - Towaco NJ, US
International Classification:
A61K 31/497
A61K 45/06
A61K 31/7068
A61K 31/4965
A61K 31/555
A61K 31/519
A61K 33/243
A61P 35/00
A61K 31/282
A61N 5/10
Abstract:
Described herein are methods of treating a proliferative disorder (e.g., cancer) in a patient by administering a DNA damaging agent and between about 12 and about 48 hours later administering to the subject a compound that inhibits ATR protein kinase. Methods of treating a proliferative disorder (e.g., cancer) in a patient by administering a compound that inhibits ATR protein kinase are also described. Exemplary ATR inhibitors are represented by Formulae A-I and A-II:or a pharmaceutically acceptable salt thereof, wherein the variables are as defined herein.

Compounds Useful As Inhibitors Of Atr Kinase And Combination Therapies Thereof

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US Patent:
20200222392, Jul 16, 2020
Filed:
Jul 10, 2019
Appl. No.:
16/507139
Inventors:
- Boston MA, US
Philip Michael Reaper - Abingdon, GB
Mohammed Asmal - Newton MA, US
International Classification:
A61K 31/496
A61K 31/4965
A61K 31/497
A61K 31/55
A61K 33/24
A61K 45/06
C07D 413/04
Abstract:
The present invention relates to compounds useful as inhibitors of ATR protein kinase and combination therapies thereof The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors.The compounds of this invention have formula I:wherein the variables are as defined herein.

Method For Treating Cancer Using A Combination Of Dna Damaging Agents And Atr Inhibitors

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US Patent:
20180303829, Oct 25, 2018
Filed:
Sep 30, 2016
Appl. No.:
15/763366
Inventors:
- Boston MA, US
Peter LITTLEWOOD - Abingdon, Oxfordshire, GB
Philip Michael REAPER - Abingdon, Oxfordshire, GB
Mohammed ASMAL - Newton MA, US
Scott Zachary FIELDS - Towaco NJ, US
International Classification:
A61K 31/497
A61K 45/06
A61K 33/24
A61K 31/7068
A61K 31/282
A61P 35/00
A61N 5/10
Abstract:
Described herein are methods of treating a proliferative disorder (e.g., cancer) in a patient by administering a DNA damaging agent and between about 12 and about 48 hours later administering to the subject a compound that inhibits ATR protein kinase. Methods of treating a proliferative disorder (e.g., cancer) in a patient by administering a compound that inhibits ATR protein kinase are also described. Exemplary ATR inhibitors are represented by Formulae A-I and A-II or a pharmaceutically acceptable salt thereof, wherein the variables are as defined herein.

Inhibitors Of Influenza Viruses Replication

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US Patent:
20160251353, Sep 1, 2016
Filed:
May 10, 2016
Appl. No.:
15/150459
Inventors:
- Boston MA, US
Michael Waldo - Grafton MA, US
Simon Adam O'Neil - Belmont MA, US
John Gregg Van Alsten - Framingham MA, US
Dainius Macikenas - Cambridge MA, US
Praveen Mudunuri - Waltham MA, US
Yi Shi - Natick MA, US
Mark Willem Ledeboer - Acton MA, US
Valdas Jurkauskas - Cambridge MA, US
Ales Medek - Winchester MA, US
Steven Jones - Hyde Park MA, US
Randal Byrn - Wayland MA, US
Mohammed Asmal - Newton MA, US
Sarah Marie Robertson - Somerville MA, US
Wanjung Tsai - Somerville MA, US
International Classification:
C07D 471/04
A61K 45/06
A61K 31/4965
A61K 31/16
A61K 31/351
A61K 31/506
C07C 309/30
Abstract:
Polymorphic forms of Compound (1) or a pharmaceutically acceptable salt thereof, wherein Compound (1) is represented by the following structural formula:are Form A of HCl salt of Compound (1).HO, Form F of HCl salt of Compound (1).3HO, Form D of HCl salt of Compound (1), Form A of Compound (1), and Form A of tosylate salt of Compound (1). Such polymorphic forms are employed for treating influenza, inhibiting the replication of influenza viruses, or reducing the amount of influenza viruses in a biological sample or in a subject.

Compounds Useful As Inhibitors Of Atr Kinase And Combination Therapies Thereof

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US Patent:
20160030424, Feb 4, 2016
Filed:
Aug 3, 2015
Appl. No.:
14/816432
Inventors:
- Cambridge MA, US
Philip Michael Reaper - Abingdon, GB
Mohammed Asmal - Newton MA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
A61K 31/496
A61K 31/55
A61K 33/24
A61K 45/06
Abstract:
The present invention relates to compounds useful as inhibitors of ATR protein kinase and combination therapies thereof. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors.The compounds of this invention have formula I:wherein the variables are as defined herein.
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Mohammed Asmal from Newton, MA, age ~51 Get Report