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Michael A Strausbauch

from Rochester, MN
Age ~68

Michael Strausbauch Phones & Addresses

  • 4404 8Th St, Rochester, MN 55901 (507) 271-0103
  • Great Falls, MT

Work

Company: Mayo clinic May 1991 Position: Senior research technologist

Education

School / High School: University of Great Falls 1974 to 1988

Skills

Molecular Biology • Stem Cells • Population Genetics • Molecular Evolution • Proteomics • Gene Expression Profiling

Industries

Hospital & Health Care

Resumes

Resumes

Michael Strausbauch Photo 1

Development Technologist

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Location:
Rochester, MN
Industry:
Hospital & Health Care
Work:
Mayo Clinic since May 1991
Senior Research Technologist

McLaughlin Research Institute May 1988 - Apr 1991
Research Tech
Education:
University of Great Falls 1974 - 1988
Central Catholic High School 1970 - 1974
Skills:
Molecular Biology
Stem Cells
Population Genetics
Molecular Evolution
Proteomics
Gene Expression Profiling

Publications

Us Patents

Complexed Polypeptide And Adjuvant For Improved Vaccines

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US Patent:
20090233871, Sep 17, 2009
Filed:
Aug 31, 2006
Appl. No.:
11/513628
Inventors:
Peter J. Wettstein - Rochester MN, US
Michael A. Strausbauch - Rochester MN, US
Nancy Borson - Rochester MN, US
International Classification:
A61K 48/00
A61K 38/10
A61K 38/08
A61K 38/06
US Classification:
514 15, 514 16, 514 17, 514 18, 514 44 A, 424 92
Abstract:
Immunogenic polypeptides having the capability to precipitate and focus a CpG adjuvant exhibit enhanced in vivo priming of a cytotoxic T-lymphocyte (CTL) response. Accordingly, compositions that include a bipartite immunogenic polypeptide are provided herein. The bipartite polypeptide includes a CpG-interacting amino acid sequence and a CTL-activating amino acid sequence. Also provided are methods of identifying and using a bipartite immunogenic polypeptide.

Assessing T Cell Repertoires

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US Patent:
20100285984, Nov 11, 2010
Filed:
Sep 26, 2008
Appl. No.:
12/680065
Inventors:
Peter J. Wettstein - Rochester MN, US
Nancy D. Borson - Rochester MN, US
Michael A. Strausbauch - Rochester MN, US
International Classification:
C40B 30/04
C12Q 1/68
US Classification:
506 9, 435 6
Abstract:
This document provides methods and materials related to assessing T cell repertoires. For example, amplification methods and materials that can be used to assess the diversity of a mammal's T cell repertoire are provided.

Complexed Polypeptide And Adjuvant For Improved Vaccines

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US Patent:
20080146488, Jun 19, 2008
Filed:
Feb 4, 2005
Appl. No.:
10/587925
Inventors:
Peter J. Wettstein - Rochester MN, US
Michael A. Strausbauch - Rochester MN, US
Heather A. Hardin - Milton WI, US
Nancy Borson - Rochester MN, US
International Classification:
A61K 38/02
A61P 35/00
US Classification:
514 2
Abstract:
Attachment of the strongly immunogenic polypeptide to a more weakly immunogenic polypeptide can precipitate and focus a CpG adjuvant to increase in vivo priming of a cytotoxic T-lymphocyte (CTL) response, and thus increase the immunogenicity of the more weakly immunogenic polypeptide. Accordingly, compositions that include a bipartite immunogenic polypeptide are provided herein. The bipartite polypeptide can include a CpG-interacting amino acid sequence fused to a CTL-activating amino acid sequence that can be heterologous to the CpG-interacting amino acid sequence. Also provided are methods of identifying and using a CpG-interacting amino acid sequence and a bipartite immunogenic polypeptide.
Michael A Strausbauch from Rochester, MN, age ~68 Get Report