Michael Lynn Carley

6942674, Sep 13, 2005

Feb 21, 2002

10/081723

W. Martin Belef - San Jose CA, US
William N. Aldrich - Napa CA, US
Michael T. Carley - San Jose CA, US
Ronald J. Jabba - Redwood City CA, US
Stephen M. Salmon - Napa CA, US
Anthony Pantages - Los Altos CA, US
Javier Sagastegui - Castro Valley CA, US

Integrated Vascular Systems, Inc. - Sunnyvale CA

A61B017/10

606142, 606213, 606139

An apparatus for delivering a clip to close an opening through tissue includes a sheath and a carrier assembly including a clip therein that is slidable on the sheath. An actuator assembly is connectable to the sheath, and telescoping actuator members extend from the handle that are connectable to the carrier assembly for advancing the carrier assembly along the sheath. An obturator on the actuator assembly includes splines that may be deployed beyond a distal end of the sheath, and expanded to a transverse expanded configuration for positioning the sheath before deploying the clip. The actuator members include cooperating detents that selectively release the actuator members as the carrier assembly reaches predetermined positions along the sheath for deploying the clip from the carrier assembly, and that collapse the splines to allow removal of the apparatus after deploying the clip.

7001398, Feb 21, 2006

Jul 9, 2003

10/617090

Michael T. Carley - San Jose CA, US
Richard S. Ginn - San Jose CA, US
Javier Sagastegui - Castro Valley CA, US
Ronald J. Jabba - Redwood City CA, US
William N. Aldrich - Napa CA, US
W. Martin Belef - San Jose CA, US

Integrated Vascular Systems, Inc. - Sunnyvale CA

A61B 17/10

606142, 606139, 606216, 606221

A method for closing an opening in a wall of a body lumen wherein an elongate member is advanced into the body lumen and a distal portion of an obturator is positioned distally beyond the distal end of the elongate member within the body lumen and in which one or more expandable elements on the distal portion of the obturator are expanded. The obturator is then withdrawn until the expandable elements contact the wall of the body lumen and a clip having tines is advanced over the elongate member until the tines penetrate the wall of the body lumen. The tines and the expandable elements are offset from one another. The elongate member is withdrawn from the body lumen and the clip substantially closes the opening in the body lumen.

7211101, May 1, 2007

Dec 31, 2002

10/335075

Michael T. Carley - San Jose CA, US
Richard S. Ginn - San Jose CA, US

Abbott Vascular Devices - Abbott Park IL

A61B 17/08
A61B 17/00

606213

The present invention relates to a method of making clips which can be used to engage body tissue for the purpose of closing wounds. Such clips are generally annular in shape and have radially inwardly extending tines. It is often desirable for such clips to have a small lateral dimension, but manufacturing difficulty has been encountered in making small clips because of the difficulty in cutting materials accurately when attempting to produce a clip with closely packed elements. The present invention avoids these difficulties by first forming a precursor which, in one embodiment, has the tines extending radially outwardly from the annular body and then forms the clip by inverting the precursor such that the tines extend radially inwardly. In an alternate embodiment, the precursor is formed with an over-sized lateral dimension and then compressed inwardly to bring the tines closer together and to reduce the lateral dimension of the precursor. It is preferred to manufacture such clips from a superelastic alloy such as nickel-titanium, in which case the inverted or compressed precursor must be heated and quenched to heat set the clip in its final shape.

7806904, Oct 5, 2010

Feb 24, 2004

10/787073

Michael T. Carley - San Jose CA, US
Richard S. Ginn - San Jose CA, US
Javier Sagastegui - Castro Valley CA, US
Janina Sagastegui, legal representative - Castro Valley CA, US
Ronald J. Jabba - Redwood City CA, US
William N. Aldrich - Napa CA, US
W. Martin Belef - San Jose CA, US

Integrated Vascular Systems, Inc. - Redwood City CA

A61B 17/08

606151

A clip for engaging tissue includes a generally annular-shaped body defining a plane and disposed about a central axis extending normal to the plane. The body includes alternating inner and outer curved regions, defining a zigzag pattern about a periphery of the clip. The body is biased towards a planar configuration lying in the plane and deflectable towards a transverse configuration extending out of the plane. Tines extend from the inner curved regions, the tines being oriented towards the central axis in the planar configuration, and parallel to the central axis in the transverse configuration. The tines include primary tines and secondary tines that are shorter than the primary tines. The primary tines may be disposed on opposing inner curved regions and oriented towards one another. The primary tines are configured such that they are offset from the axes of symmetry of the curved regions from which they extend and are connected to the curved regions by curved or linear regions or are connected directly to the curved regions. The primary tines may overlap the body and may be of different lengths.

7828817, Nov 9, 2010

Aug 4, 2005

11/198811

W. Martin Belef - San Jose CA, US
William N. Aldrich - Napa CA, US
Michael T. Carley - San Jose CA, US
Ronald J. Jabba - Redwood City CA, US
Stephen M. Salmon - Napa CA, US
Anthony Pantages - Los Altos CA, US
Javier Sagastegui - Castro Valley CA, US

Integrated Vascular Systems, Inc. - Redwood City CA

A61B 17/08

606213, 606219, 606232, 606151, 606153, 606139

An apparatus for delivering a clip to close an opening through tissue includes a sheath and a carrier assembly including a clip therein that is slidable on the sheath. An actuator assembly is connectable to the sheath, and telescoping actuator members extend from the handle that are connectable to the carrier assembly for advancing the carrier assembly along the sheath. An obturator on the actuator assembly includes splines that may be deployed beyond a distal end of the sheath, and expanded to a transverse expanded configuration for positioning the sheath before deploying the clip. The actuator members include cooperating detents that selectively release the actuator members as the carrier assembly reaches predetermined positions along the sheath for deploying the clip from the carrier assembly, and that collapse the splines to allow removal of the apparatus after deploying the clip.

7850797, Dec 14, 2010

Mar 12, 2009

12/403256

Michael T. Carley - San Jose CA, US
Richard S. Ginn - San Jose CA, US

Integrated Vascular Systems, Inc. - Santa Clara CA

C22F 1/00
A61B 17/08

148563, 606151

The present invention relates to a method of making clips which can be used to engage body tissue for the purpose of closing wounds. Such clips are generally annular in shape and have radially inwardly extending tines. The present invention first forms a precursor which, in one embodiment, has the tines extending radially outwardly from the annular body and then forms the clip by inverting the precursor such that the tines extend radially inwardly. In an alternate embodiment, the precursor is formed with an over-sized lateral dimension and then compressed inwardly to bring the tines closer together and to reduce the lateral dimension of the precursor. It is preferred to manufacture such clips from a superelastic alloy such as nickel-titanium, in which case the inverted or compressed precursor must be heated and quenched to heat set the clip in its final shape.

7854810, Dec 21, 2010

Dec 17, 2003

10/541083

Michael T. Carley - San Jose CA, US
Richard S. Ginn - San Jose CA, US

Integrated Vascular Systems, Inc. - Redwood City CA

C22F 1/00
A61B 17/08

148563, 606151

The present invention relates to a method of making clips which can be used to engage body tissue for the purpose of closing wounds. Such clips are generally annular in shape and have radially inwardly extending tines. The present invention first forms a precursor which, in one embodiment, has the tines extending radially outwardly from the annular body and then forms the clip by inverting the precursor such that the tines extend radially inwardly. In an alternate embodiment, the precursor is formed with an over-sized lateral dimension and then compressed inwardly to bring the tines closer together and to reduce the lateral dimension of the precursor. It is preferred to manufacture such clips from a superelastic alloy such as nickel-titanium, in which case the inverted or compressed precursor must be heated and quenched to heat set the clip in its final shape.

7867249, Jan 11, 2011

Aug 8, 2003

10/638115

Thomas J Palermo - San Jose CA, US
William M Belef - San Jose CA, US
Michael T Carley - San Jose CA, US
Richard S Ginn - San Jose CA, US
Ronald J Jabba - Redwood City CA, US
Anthony Pantages - Los Altos CA, US

Integrated Vascular Systems, Inc. - Redwood City CA

A61B 17/08

606213

An apparatus for delivering a closure element into an opening formed in a blood vessel or other body lumen and methods for manufacturing and using same. The apparatus is configured to retain the closure element such that the closure element is disposed substantially within the apparatus. The apparatus also can engage, and position the closure element substantially adjacent to, the blood vessel wall adjacent to the opening. During deployment of the closure element, the apparatus expands the closure element beyond a natural cross-section of the closure element such that the closure element, when deployed, is configured to engage a significant amount of the blood vessel wall and/or tissue. Engaging the blood vessel wall and/or tissue, the closure element is further configured to return to the natural cross-section, thereby drawing the engaged blood vessel wall and/or tissue substantially closed and/or sealed, such that hemostasis within the opening is enhanced.