Michael F Bregen

53062809, Apr 26, 1994

Aug 5, 1992

7/926099

Michael Bregen - Lebanon NJ
Brian H. Luscombe - Washington Crossing PA

Ethicon, Inc. - Somerville NJ

A61B 1700

606143

A method of clamping suture strand by applying heat and compressive force to a polymeric surgical clip having first and second opposed leg members so as to clamp the suture strand between the opposed inner clamping surfaces of the first and second leg members; a surgical clip defined by first and second leg members, the first leg member having a hole therein; and a surgical device for clamping a clip about a suture, such device defined by a trigger-activated handle, clamping jaws with a heating element disposed on one of the clamping members of the clamping jaws, a shaft connecting the jaws to the handle, and means for activating the heating element and for delivering compressive force to the clamping jaws to close the clip about a suture.

55501729, Aug 27, 1996

Feb 7, 1995

8/385015

Donald W. Regula - Belle Mead NJ
Kevin Cooper - Warren NJ
Michael F. Bregen - Milford NJ
Shawn T. Huxel - Lakehurst NJ
Daniel C. Rosenman - San Mateo CA

Ethicon, Inc. - Somerville NJ

C08K 510
A61B 1756
A61B 1758
C01B 1516

523118

A process for enhancing the security of implantable surgical devices secured to bone tissue comprising implanting in bone tissue a surgical device with a biocompatible adhesive and/or sealant selected from the group consisting of: p1 (a) a material made from monomers of the formula: CHR. sup. 1. dbd. CX. sup. 1 Y. sup. 1 wherein X. sup. 1 and Y. sup. 1 are each strong electron withdrawing groups, and R. sup. 1 is hydrogen or, provided that X. sup. 1 and Y. sup. 1 are both cyano groups, a C. sub. 1 -C. sub. 4 alkyl group; (b) a semi-crystalline aliphatic poly(ester) of the formula: [--0--R. sup. 11 --C(0)--]. sub. y, wherein R. sup. 11 is selected from the group consisting of --CR. sup. 12 H--, --(CH. sub. 2). sub. 3 --0--, --CH. sub. 2 --CH. sub. 2 --O--CH. sub. 2 --, CR. sub. 12 H--CH. sub. 2, --(CH. sub. 2). sub.

51712512, Dec 15, 1992

Mar 2, 1992

7/844253

Michael Bregen - Lebanon NJ
Brian H. Luscombe - Washington Crossing PA

Ethicon, Inc. - Somerville NJ

A61B 1700

606151

A method of clamping suture strand by applying heat and compressive force to a polymeric surgical clip having first and second opposed leg members so as to clamp the suture strand between the opposed inner clamping surfaces of the first and second leg members; a surgical clip defined by first and second leg members, the first leg member having a hole therein; and a surgical device for clamping a clip about a suture, such device defined by a trigger-activated handle, clamping jaws with a heating element disposed on one of the clamping members of the clamping jaws, a shaft connecting the jaws to the handle, and means for activating the heating element and for delivering compressive force to the clamping jaws to close the clip about a suture.

57281351, Mar 17, 1998

Feb 9, 1996

8/598886

Michael Francis Bregen - Milford NJ
John Paul Measamer - Cincinnati OH

Ethicon, Inc. - Somerville NJ

A61B 1704

606228

A suture for use in a laparoscopic suturing device comprising a suture having a first and second end. The first end being attached to a surgical needle and the second end being attached to a retainer wherein the adjacent to the retainer there is a stiffened segment of the suture.

53042042, Apr 19, 1994

Feb 9, 1993

8/015707

Michael F. Bregen - Lebanon NJ

Ethicon, Inc. - Somerville NJ

A61B 1700

606219

A self-closing receiverless surgical fastener comprises a fastener body of biocompatible or bioabsorbable material including a bridge member and at least two tines extending from opposite ends of the bridge member. The tines are resiliently deformable from a normally closed position with the distal ends of the tines pointing toward each other to an open position with the distal ends of the tines extending substantially parallel to each other for penetrating into tissue. The tines are resiliently returnable to the closed position with the distal ends of the tines pointing toward each other to secure the fastener body to the tissue.

56749210, Oct 7, 1997

Feb 1, 1995

8/382325

Donald W. Regula - Belle Meade NJ
Michael F. Bregen - Lebanon NJ
Stuart L. Cooper - Wilmington DE
Dennis D. Jamiolkowski - Long Valley NJ
Rao S. Bezwada - Whitehouse Station NJ

Ethicon, Inc. - Somerville NJ

A61B 1708
G03C 500
B29C 3502
C08L 7516

522 97

A radiation-curable prepolymer of a polyurethane endtipped with an hydroxy (acrylate or methacrylate) is disclosed. The polyurethane is derived from the reaction of a polyfunctional isocyanate with a hydrolyzable oligomer of an anhydrous cyclic ester of an hydroxy acid. Crosslinked polymers prepared by irradiating the prepolymers are also disclosed. The crosslinked polymers are bioabsorbable and biocompatible with bodily tissue, yet still maintain the outstanding mechanical properties one would expect from a polyurethane. The prepolymers and crosslinked polymers are especially well-suited for the fabrication of surgical devices, particularly wound closure devices such as surgical staples and clips, in a stereolithography apparatus.

53465016, Sep 13, 1994

Feb 5, 1993

8/014019

Donald W. Regula - Belle Meade NJ
Michael F. Bregen - Lebanon NJ
Zoltan Szabo - San Francisco CA
Barry N. Gardiner - Orinda CA

Ethicon, Inc. - Somerville NJ

A61B 1700

606151

A mechanism and applier therefor which is capable of inverted anastomosis of two lumens by an absorbable fastener. The fastener is made from two washer-like plate assemblies and a pair of introducers. Each such plate assembly has slots to receive latching prongs protruding from the other plate, and pins to impale tissue. Fastening is done through an applier that causes the pins to pierce the tissue, and causes a knife blade to cut through excess tissue. Fastening is done by attaching fastener halves. Insertion and removal of the fastener and applier optimally is done in an endoscopic procedure through a trocar or through the surgical incision in an open procedure. The system can be used such that the plates can be placed to properly set gaps between and anastomose tissue. The introducer portion will soften intraluminally and be expelled, in about 24 hours. The coupler portion will remain in place for 2-3 weeks, typically, and then fragment and be expelled with the feces.