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Michael A Blanar

from Des Moines, IA
Age ~65
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Also known as:
Michael Alois Blanar, Michael Alois Blaner, Michael Blanar Alois, Alois Blanar Michael
Related to:
Sarah O Donnella, 37Thomas R Cronkhite, 61Gregory A Stemas, 57Vogel CronkhiteRoland F CronkhiteBarton J Vogel, 65Roland Cronkhite, 86Christopher P Cronkhite, 59Dolly J Vogel, 92Howard C VogelJulie M Vogel, 64
Connected to:
Anna T Blanar, 101Patrick Blanar, 32Jamie K Blanarik, 43Orest Blanarovich, 48Dorina Blanaru, 62Paul Blanas, 34Alain J Blanc, 80Alta Blanc, 58Ashley C Blanc, 48Carline J Blanc, 53

Michael Blanar Phones & Addresses

  • Des Moines, IA
  • Johnston, IA
  • Wayne, PA
  • 1325 Summerhill Dr, Malvern, PA 19355 (610) 251-0230
  • Wilmington, DE
  • San Francisco, CA

Work

Company: Bristol-myers squibb 2003 to 2009 Position: Group director

Education

School / High School: University of California, San Francisco - School of Medicine 1989 to 1993

Skills

Arthritis • Research • Biochemistry • Biophysics • Gene Expression

Industries

Pharmaceuticals

Resumes

Resumes

Michael Blanar Photo 1

Michael Blanar

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Location:
5221 northwest 70Th Pl, Johnston, IA 50131
Industry:
Pharmaceuticals
Work:
Bristol-Myers Squibb 2003 - 2009
Group Director
Princeton University 1996 - 2004
Visiting Research Scholar
Ucsf Medical Center 1989 - 1993
Postdoc
Biogen 1985 - 1988
Arthritis Foundation Postdoctoral Fellow
Education:
University of California, San Francisco - School of Medicine 1989 - 1993
University of California, Berkeley 1980 - 1985
Brandon University 1977 - 1980
University of California, San Francisco - School of Medicine
Skills:
Arthritis
Research
Biochemistry
Biophysics
Gene Expression

Publications

Us Patents

Dna Encoding Rodent Kcnq2 Potassium Channel

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US Patent:
7041496, May 9, 2006
Filed:
Apr 24, 2002
Appl. No.:
10/128870
Inventors:
Michael A. Blanar - Malvern PA, US
Steven Dworetzky - Middlefield CT, US
Wen-Pin Yang - Princeton NJ, US
Paul C. Levesque - Yardley PA, US
Valentin K. Gribkoff - Wallingford CT, US
Michael G. Neubauer - Skillman NJ, US
Wayne A. Little - Pottstown PA, US
Assignee:
Bristol-Myers Squibb - Princeton NJ
International Classification:
C12N 15/11
C12N 5/10
C12N 15/63
US Classification:
4353201, 435325, 536 235
Abstract:
The present invention relates to KCNQ proteins defining potassium channels. In particular, the invention concerns the human KCNQ2, human KCNQ3, murine KCNQ2, and rat KCNQ2 proteins reported herein. KCNQ2 and KCNQ3 proteins are nervous system-selective and may be involved in neurotransmission and neuroprotection. The KCNQ2 and KCNQ3 of the present invention can be used to assay for modulators of the proteins, which would be useful in treatment of such disorders as ataxia, myokymia, seizures, Alzheimer's disease, Parkinson's disease, age-associated memory loss, learning deficiencies, motor neuron diseases, epilepsy, stroke, and the like.

Polynucleotide Encoding A Trp Channel Family Member, Trp-Plik2

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US Patent:
7223557, May 29, 2007
Filed:
May 22, 2002
Appl. No.:
10/153244
Inventors:
Ning Lee - Belle Mead NJ, US
Jian Chen - Princeton NJ, US
John N. Feder - Belle Mead NJ, US
Shujian Wu - Langhorne PA, US
Han Chang - Princeton Junction NJ, US
Liana M. Le - San Francisco CA, US
Michael A. Blanar - Malvern PA, US
David Bol - Gaithersburg MD, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C12Q 1/68
C07H 21/04
C12P 21/02
C12N 5/06
C07K 14/705
US Classification:
435 691, 435 701, 4352523, 435325, 4353201, 530350, 536 231, 536 235
Abstract:
The present invention provides novel polynucleotides encoding TRP-PLIK2 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding variants and splice variants of TRP-PLIK2 polypeptides, TRP-PLIK2b, TRP-PLIK2c, and TRP-PLIK2d, respectively. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel TRP-PLIK2, TRP-PLIK2b, TRP-PLIK2c, and TRP-PLIK2d polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

Polynucleotides Encoding Variants Of The Trp Channel Family Member, Ltrpc3

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US Patent:
7344882, Mar 18, 2008
Filed:
May 10, 2004
Appl. No.:
10/842313
Inventors:
Ning Lee - Belle Mead NJ, US
Jian Chen - Princeton NJ, US
Shujian Wu - Langhorne PA, US
Michael A. Blanar - Malvern PA, US
Paul C. Levesque - Yardley PA, US
Lucy Sun - Newtown PA, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C12N 5/10
C12N 15/12
C12N 15/63
C12N 1/21
US Classification:
435325, 435 691, 4352523, 4353201, 530350, 536 235
Abstract:
The present invention provides novel polynucleotides encoding LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides, fragments and homologues thereof Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

Variants Of The Trp Channel Family Member, Ltrpc3G

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US Patent:
7459532, Dec 2, 2008
Filed:
Nov 19, 2007
Appl. No.:
11/985981
Inventors:
Ning Lee - Belle Mead NJ, US
Jian Chen - Princeton NJ, US
Shujian Wu - Langhorne PA, US
Michael A. Blanar - Malvern PA, US
Paul C. Levesque - Yardley PA, US
Lucy Sun - Newtown PA, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07K 14/435
C07K 14/705
C12P 21/02
A61K 38/17
US Classification:
530350, 514 2, 514 12, 536 235, 435 691
Abstract:
The present invention provides novel polynucleotides encoding LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

Kcnq2 Potassium Channels

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US Patent:
7482431, Jan 27, 2009
Filed:
Feb 16, 2007
Appl. No.:
11/707363
Inventors:
Michael A. Blanar - Malvern PA, US
Paul C. Levesque - Yardley PA, US
Wayne A. Little - Pottstown PA, US
Michael G. Neubauer - Skillman NJ, US
Wen-Pin Yang - Princeton NJ, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07K 14/705
US Classification:
530350
Abstract:
The present invention relates to KCNQ proteins defining potassium channels. In particular, the invention concerns the human KCNQ2, human KCNQ3, murine KCNQ2, and rat KCNQ2 proteins reported herein. KCNQ2 and KCNQ3 proteins are nervous system-selective and may be involved in neurotransmission and neuroprotection. The KCNQ2 and KCNQ3 of the present invention can be used to assay for modulators of the proteins, which would be useful in treatment of such disorders as ataxia, myokymia, seizures, Alzheimer's disease, Parkinson's disease, age-associated memory loss, learning deficiencies, motor neuron diseases, epilepsy, stroke, and the like.

Trp Channel Family Member, Ltrpc3 Polypeptides

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US Patent:
7504481, Mar 17, 2009
Filed:
Mar 28, 2003
Appl. No.:
10/405793
Inventors:
Ning Lee - Belle Mead NJ, US
Jian Chen - Princeton NJ, US
John N. Feder - Belle Mead NJ, US
Shujian Wu - Langhorne PA, US
Liana M. Lee - Somerset NJ, US
Michael A. Blanar - Malvern PA, US
Assignee:
Bristol-Meyers Squibb Company - Princeton NJ
International Classification:
C07K 1/00
C12P 21/06
C12P 21/04
C12N 15/00
A61K 39/00
US Classification:
530350, 435 691, 435 697, 4353201, 4241921
Abstract:
The present invention provides novel polynucleotides encoding LTRPC3 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding variants and splice variants of LTRPC3 polypeptides, LTRPC3b, LTRPC3c, LTRPC3d, LTRPC3e, and LTRPC3f, respectively. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing the novel LTRPC3, LTRPC3b, LTRPC3c, LTRPC3d, LTRPC3e, and LTRPC3f polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel LTRPC3, LTRPC3b, LTRPC3c, LTRPC3d, LTRPC3e, and LTRPC3f polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

Polypeptide For A Trp Channel Family Member, Trp-Plik2, And Splice Variants

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US Patent:
7541434, Jun 2, 2009
Filed:
Mar 21, 2007
Appl. No.:
11/726234
Inventors:
Ning Lee - Belle Mead NJ, US
Jian Chen - Princeton NJ, US
Shujian Wu - Langhorne PA, US
Han Chang - Princeton Junction NJ, US
Michael A. Blanar - Malvern PA, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07K 14/47
C12N 15/07
C12N 15/64
C12P 21/02
US Classification:
530350, 435 691, 4353201, 435325, 435471
Abstract:
The present invention provides novel polynucleotides encoding TRP-PLIK2 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding variants and splice variants of TRP-PLIK2 polypeptides, TRP-PLIK2b, TRP-PLIK2c, and TRP-PLIK2d, respectively. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel TRP-PLIK2, TRP-PLIK2b, TRP-PLIK2c, and TRP-PLIK2d polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

Antibodies Which Bind Variants Of The Trp Channel Family Member, Ltrpc3

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US Patent:
7705133, Apr 27, 2010
Filed:
Jul 22, 2008
Appl. No.:
12/220155
Inventors:
Ning Lee - Belle Mead NJ, US
Jian Chen - Princeton NJ, US
Shujian Wu - Langhorne PA, US
Michael A. Blanar - Malvern PA, US
Paul C. Levesque - Yardley PA, US
Lucy Sun - Newtown PA, US
Assignee:
Bristol-Myers Squibb Company - Preinceton NJ
International Classification:
C07K 16/28
C07K 16/18
A61K 39/395
US Classification:
5303879, 5303873, 5303881, 53038815, 53038822, 4241301, 4241331, 4241391, 4241431
Abstract:
The present invention provides novel polynucleotides encoding LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
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Michael A Blanar from Des Moines, IA, age ~65 Get Report