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Micah J Niphakis

from San Diego, CA
Age ~41
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Related to:
Ricky F Martin, 69Claudia S Morrissey, 40Kathleen L Patton, 38Emma G Higgins, 35Easten W Niphakis, 42Laurie L Higgins, 70Steve Niphakis, 75Nathan S Niphakis, 43Holly L Niphakis, 70Allison Niphakis, 39Chris NiphakisJohn B Higgins, 40Stavros Niphakis, 75
Connected to:
Walter V Nipiossian, 65Pearl Nipon, 96Chad M Nipp, 39Gordon L Nipp, 84Scott V Nipp, 53Thomas N Nipp, 83Derek B Nippe, 62Allison Nipper, 43Caroline Nipper, 34Celia Nipper, 68

Micah Niphakis Phones & Addresses

  • 10912 Promesa Dr, San Diego, CA 92124
  • Minneapolis, MN
  • Lawrence, KS
  • Dallastown, PA
  • 7911 Camino Kiosco, San Diego, CA 92122

Education

Degree: Associate degree or higher

Resumes

Resumes

Micah Niphakis Photo 1

Principal Scientist

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Location:
San Diego, CA
Industry:
Biotechnology
Work:
The Scripps Research Institute since Sep 2010
Research Associate, Cravatt Lab
Institute for Therapeutics Discovery and Development, University of Minnesota 2007 - Jul 2010
Research Specialist, Georg Lab
Education:
University of Kansas 2005 - 2010
Ph.D., Medicinal Chemistry Houghton College 2001 - 2005
B.Sc., Chemistry
Skills:
Organic Synthesis
Drug Discovery
Medicinal Chemistry
Nmr
Organic Chemistry
Lc Ms
Mass Spectrometry
Purification
Drug Design
Chemistry
Cell Culture
Protein Chemistry
Molecular Biology
Micah Niphakis Photo 2

Greater Minneapolis-St Paul Area

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Location:
Minneapolis, MN
Industry:
Research
Work:

Greater Minneapolis-St Paul Area
Education:
University of Kansas 2005 - 2011

Publications

Us Patents

Lipid Probes And Uses Thereof

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US Patent:
20190293666, Sep 26, 2019
Filed:
Dec 28, 2018
Appl. No.:
16/235096
Inventors:
- La Jolla CA, US
Micah J. Niphakis - San Diego CA, US
Kenneth Lum - San Diego CA, US
Bruno Correia - Blemblens, CH
Armand Cognetta - San Diego CA, US
Jonathan Hulce - Libertyville IL, US
International Classification:
G01N 33/92
G01N 33/68
Abstract:
Disclosed herein are methods, compositions, probes, assays and kits for identifying a lipid binding protein as a drug binding target. Also disclosed herein are methods, compositions, and probes for mapping a ligand binding site on a lipid binding protein, identification of lipid binding proteins, generating drug-lipid binding protein profiles, high throughput drug screening, and identification of drugs as potential lipid binding protein ligands.

Lp-Pla2 Inhibitors

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US Patent:
20180282288, Oct 4, 2018
Filed:
Sep 29, 2016
Appl. No.:
15/764231
Inventors:
- San Diego CA, US
Micah NIPHAKIS - San Diego CA, US
Todd K. JONES - Solana Beach CA, US
International Classification:
C07D 233/80
Abstract:
Provided herein are lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitors, pharmaceutical compositions of said inhibitors, and methods of their use for the treatment of disease.

Carbamate Compounds And Methods Of Making And Using Same

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US Patent:
20180208568, Jul 26, 2018
Filed:
Mar 19, 2018
Appl. No.:
15/925517
Inventors:
- San Diego CA, US
- La Jolla CA, US
Todd K. JONES - Solana Beach CA, US
Micah J. NIPHAKIS - San Diego CA, US
Jae Won CHANG - San Diego CA, US
Kenneth M. LUM - San Diego CA, US
Benjamin F. CRAVATT - San Diego CA, US
International Classification:
C07D 295/205
C07D 491/107
C07C 271/10
C07D 471/10
C07D 471/04
C07D 413/10
C07D 413/06
C07D 407/06
C07D 405/14
C07D 403/10
C07D 401/10
C07D 401/04
C07D 317/58
C07D 317/46
C07D 307/79
C07D 295/26
C07D 271/06
C07D 263/32
C07D 261/08
C07D 241/04
C07D 231/56
C07D 231/16
C07D 231/12
C07D 215/46
C07D 215/42
C07D 213/55
C07D 213/40
C07D 213/38
C07D 207/14
C07D 207/09
C07D 205/04
C07C 271/12
C07D 487/04
Abstract:
This disclosure provides compounds and compositions which may be modulators of MAGL and/or ABHD6 and their use as medicinal agents, processes for their preparation, and pharmaceutical compositions that include disclosed compounds as at least one active agent. The disclosure also provides for method of treating a patient in need thereof, where the patient is suffering from indications such as pain, solid tumor cancer and/or obesity comprising administering a disclosed compound or composition.

N-Hydroxy Bicyclic Hydantoin Carbamates As Tools For Indetification Of Serine Hydrolase Targets

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US Patent:
20170183353, Jun 29, 2017
Filed:
May 20, 2015
Appl. No.:
15/313012
Inventors:
- San Diego CA, US
- La Jolla CA, US
Jonathan J. HULCE - San Diego CA, US
Micah J. NIPHAKIS - San Diego CA, US
Todd K. JONES - Solana Beach CA, US
Cheryl A. GRICE - Encinitas CA, US
International Classification:
C07D 487/04
C12Q 1/34
Abstract:
Provided herein are N-hydroxy bicyclic hydantoin carbamates and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of serine hydrolases. Furthermore, the subject compounds and compositions are useful for the treatment of one or more of cancer, pain, diabetes, obesity/metabolic syndrome, epilepsy, traumatic brain injury, and inflammation.

Carbamate Compounds And Methods Of Making And Using Same

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US Patent:
20170073320, Mar 16, 2017
Filed:
Sep 21, 2016
Appl. No.:
15/272313
Inventors:
- San Diego CA, US
Cheryl A. GRICE - Encinitas CA, US
Todd K. JONES - Solana Beach CA, US
Micah J. NIPHAKIS - San Diego CA, US
Jae Won CHANG - San Diego CA, US
Kenneth M. LUM - San Diego CA, US
Benjamin F. CRAVATT - La Jolla CA, US
International Classification:
C07D 295/205
C07D 307/79
C07D 215/46
C07D 295/26
C07D 263/32
C07D 231/56
C07D 213/38
C07D 413/10
C07D 403/10
C07D 401/10
C07D 231/12
C07D 207/14
C07D 231/16
C07D 491/107
C07D 471/10
C07D 205/04
C07D 471/04
C07D 487/04
C07D 317/58
Abstract:
This disclosure provides compounds and compositions which may be modulators of MAGL and/or ABHD6 and their use as medicinal agents, processes for their preparation, and pharmaceutical compositions that include disclosed compounds as at least one active agent. The disclosure also provides for method of treating a patient in need thereof, where the patient is suffering from indications such as pain, solid tumor cancer and/or obesity comprising administering a disclosed compound or composition.

Lipid Probes And Uses Thereof

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US Patent:
20160282369, Sep 29, 2016
Filed:
Mar 25, 2016
Appl. No.:
15/080767
Inventors:
Benjamin F. Cravatt - La Jolla CA, US
Micah J. Niphakis - San Diego CA, US
Kenneth Lum - San Diego CA, US
Bruno Correia - Bremblens, CH
Armand Cognetta - San Diego CA, US
International Classification:
G01N 33/92
G01N 33/68
Abstract:
Disclosed herein are methods, compositions, probes, assays and kits for identifying a lipid binding protein as a drug binding target. Also disclosed herein are methods, compositions, and probes for mapping a ligand binding site on a lipid binding protein, identification of lipid binding proteins, generating drug-lipid binding protein profiles, high throughput drug screening, and identification of drugs as potential lipid binding protein ligands.

Carbamate Compounds And Of Making And Using Same

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US Patent:
20150148330, May 28, 2015
Filed:
Jan 16, 2015
Appl. No.:
14/599105
Inventors:
- San Diego CA, US
- La Jolla CA, US
Todd K. Jones - Solana Beach CA, US
Micah J. Niphakis - San Diego CA, US
Jae Won Chang - San Diego CA, US
Kenneth M. Lum - San Diego CA, US
Benjamin F. Cravatt - La Jolla CA, US
International Classification:
C07D 295/26
C07D 487/04
C07D 471/04
C07D 263/32
C07D 471/10
C07D 317/58
C07C 271/10
C07D 241/04
C07D 207/09
C07D 491/107
C07D 231/56
US Classification:
51421018, 5142102, 5142358, 514249, 51425304, 51425306, 51425311, 51425401, 51425402, 51425405, 51425406, 51425411, 51425501, 544121, 544230, 544349, 544362, 544363, 544364, 544369, 544371, 544372, 544377, 544383, 544389
Abstract:
This disclosure provides compounds and compositions which may be modulators of MAGL and/or ABHD6 and their use as medicinal agents, processes for their preparation, and pharmaceutical compositions that include disclosed compounds as at least one active agent. The disclosure also provides for method of treating a patient in need thereof, where the patient is suffering from indications such as pain, solid tumor cancer and/or obesity comprising administering a disclosed compound or composition.

Carbamate Compounds And Of Making And Using Same

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US Patent:
20150080364, Mar 19, 2015
Filed:
Mar 15, 2013
Appl. No.:
14/383076
Inventors:
- San Diego CA, US
- La Jolla CA, US
Todd K. Jones - Solana Beach CA, US
Dong-Hui Wang - San Diego CA, US
Olivia Weber - San Diego CA, US
Benjamin F. Cravatt - La Jolla CA, US
Micah J. Niphakis - San Diego CA, US
Armand Cognetta - San Diego CA, US
Jae Won Chang - San Diego CA, US
Assignee:
Abide Therapeutics, Inc. - San Diego CA
The Scripps Research Insititute - La Jolla CA
International Classification:
C07D 207/46
C07D 401/12
C07D 487/04
C07D 491/107
C07D 471/04
C07D 405/14
C07D 413/12
US Classification:
51421018, 546197, 514321, 544372, 51425401, 546208, 514326, 5462787, 514343, 548131, 514364, 544130, 5142355, 544363, 51425306, 548523, 548542, 514425, 544121, 5142358, 544362, 51425304, 544350, 514249
Abstract:
Provided herein are carbamate compounds which may be useful in the treatment of for example, pain, solid tumors and/or obesity.
Control profile
Micah J Niphakis from San Diego, CA, age ~41 Get Report