Inventors:
Edmond J. LaVoie - Princeton Junction NJ
Jung Sun Kim - Pusan, KR
Meera Rangarajan - Highland Park NJ
Leroy Fong Liu - Bridgewater NJ
Assignee:
Rutgers, The State University of New Jersey - New Brunswick NJ
International Classification:
A61K 314184
Abstract:
The invention provides a topoisomerase poison of formula I: wherein R -R have any of the meanings defined in the specification, or a pharmaceutically acceptable salt thereof, as well as pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, and therapeutic methods comprising administering a compound of formula I or a salt thereof.