US Patent:
20130089599, Apr 11, 2013
Inventors:
Mauris N. DeSilva - Austin TX, US
Karen O'Connor - Scoresby, AU
Amer Tiba - Chicago IL, US
Assignee:
The United States of America as Represented by the Secretary of the Navy - Arlington VA
International Classification:
A61K 9/51
US Classification:
424450, 424490, 424493, 977773, 977906, 977907
Abstract:
This invention relates to a method to provide immediate, direct and controlled time release of an effective amount of therapeutics to a wound site for a prolonged period. The pharmaceutical formulation comprising a plurality of nanoparticles, said nanoparticles encapsulating a therapeutically effective amount of one or more antibacterial agents, and an application of the formulation to an implant before surgery provide for extended release of said antibacterial agents.