Search

Matthew E Pokross

from Yardley, PA
Age ~48

Matthew Pokross Phones & Addresses

  • 231 Yellow Springs Ct, Morrisville, PA 19067 (513) 290-4835
  • Yardley, PA
  • Hamilton, OH
  • Sylvania, OH
  • Loveland, OH
  • Lafayette, IN
  • Buck, PA
  • 231 Yellow Springs Ct, Yardley, PA 19067

Work

Position: Clerical/White Collar

Education

Degree: Associate degree or higher

Publications

Us Patents

Crystal Of Hypoxia Inducible Factor 1 Alpha Prolyl Hydroxylase

View page
US Patent:
7588924, Sep 15, 2009
Filed:
Mar 5, 2007
Appl. No.:
11/713941
Inventors:
Artem Gennady Evdokimov - Loveland OH, US
Richard Masaru Kawamoto - Lebanon OH, US
Angelique Sun Boyer - West Chester OH, US
Marlene Jan Mekel - Ross OH, US
Matthew Eugene Pokross - Hamilton OH, US
Assignee:
Procter & Gamble Company - Cincinnati OH
International Classification:
C12N 9/02
US Classification:
435189
Abstract:
The crystal structure of ligand-bound EGLN1 catalytic domain of prolyl hydroxylase is disclosed. These coordinates are useful in computer aided drug design for identifying compounds that regulate EGLN1 prolyl hydroxylase and thereby regulate HIF-regulated disorders.

Three Dimensional Coordinates Of Hptpbeta

View page
US Patent:
7769575, Aug 3, 2010
Filed:
Mar 23, 2009
Appl. No.:
12/409111
Inventors:
Artem Gennady Evdokimov - Loveland OH, US
Matthew Eugene Pokross - Loveland OH, US
Assignee:
Warner Chilcott, LLC - Fajardo PR
International Classification:
C12N 9/14
G01N 31/00
G06G 7/58
US Classification:
703 11, 436 4, 436195, 703 21
Abstract:
The crystal structures of catalytic domain of HPTPbeta, both ligand-bound and ligand-free are described. These structures are useful in computer aided drug design for identifying compounds that bind or activate HPTPbeta and thereby modulate angiogenesis mediated disorders or diseases.

Crystal Of Hypoxia Inducible Factor 1 Alpha Prolyl Hydroxylase

View page
US Patent:
8050873, Nov 1, 2011
Filed:
May 28, 2009
Appl. No.:
12/473536
Inventors:
Artem Gennady Evdokimov - Loveland OH, US
Richard Masaru Kawamoto - Lebanon OH, US
Angelique Sun Boyer - West Chester OH, US
Marlene Jan Mekel - Ross OH, US
Matthew Eugene Pokross - Hamilton OH, US
Assignee:
Warner Chilcott Company - Fajardo PR
International Classification:
G01N 31/00
G01N 33/567
G06G 7/58
C12Q 1/26
US Classification:
702 27, 703 11, 435 25, 435 721
Abstract:
The crystal structure of ligand-bound EGLN1 catalytic domain of prolyl hydroxylase is disclosed. These coordinates are useful in computer aided drug design for identifying compounds that regulate EGLN1 prolyl hydroxylase and thereby regulate HIF-regulated disorders.

Crystal Of Hypoxia Inducible Factor 1 Alpha Prolyl Hydroxylase

View page
US Patent:
8512972, Aug 20, 2013
Filed:
Sep 12, 2011
Appl. No.:
13/230548
Inventors:
Artem Gennady Evdokimov - Loveland OH, US
Richard Masaru Kawamoto - Lebanon OH, US
Angelique Sun Boyer - West Chester OH, US
Marlene Jan Mekel - Ross OH, US
Matthew Eugene Pokross - Hamilton OH, US
Assignee:
Akebia Therapeutics, Inc. - Cincinnati OH
International Classification:
C12Q 1/26
G01N 31/00
G06G 7/58
US Classification:
435 25, 702 27, 703 11, 703 12
Abstract:
The crystal structure of ligand-bound EGLN1 catalytic domain of prolyl hydroxylase is disclosed. These coordinates are useful in computer aided drug design for identifying compounds that regulate EGLN1 prolyl hydroxylase and thereby regulate HIF-regulated disorders.

Three Dimensional Coordinates Of Hptpbeta

View page
US Patent:
20040077065, Apr 22, 2004
Filed:
Aug 4, 2003
Appl. No.:
10/634027
Inventors:
Artem Evdokimov - Loveland OH, US
Matthew Pokross - Loveland OH, US
Assignee:
The Procter & Gamble Company
International Classification:
G06F019/00
G01N033/48
G01N033/50
C12N009/64
US Classification:
435/226000, 702/019000
Abstract:
The crystal structures of catalytic domain of HPTPbeta, both ligand-bound and ligan-free are described. These structures are useful in computer aided drug design for identifying compounds that bind or activate HPTPbeta and thereby modulate angiogenesis mediated disorders or diseases.

Phenethylamino Sulfamic Acids

View page
US Patent:
20040167183, Aug 26, 2004
Filed:
Aug 4, 2003
Appl. No.:
10/633743
Inventors:
Sean Klopfenstein - Loveland OH, US
Matthew Maier - Cincinnati OH, US
David Jones - Milford OH, US
Jeffrey Gray - Loveland OH, US
Matthew Pokross - Loveland OH, US
Kevin Peters - Loveland OH, US
Artem Evdokimov - Loveland OH, US
Assignee:
The Procter & Gamble Company
International Classification:
C07D213/36
A61K031/185
A61K031/44
US Classification:
514/357000, 514/553000, 514/408000, 562/037000, 546/329000
Abstract:
Compounds of formula (I): are effective in the treatment of protein tyrosine phosphatase (PTPase) mediated disorders such as diabetes.

Tetrahydroisoquinolnyl Sulfamic Acids

View page
US Patent:
20050154011, Jul 14, 2005
Filed:
Aug 4, 2003
Appl. No.:
10/633744
Inventors:
Sean Klopfenstein - Loveland OH, US
Matthew Maier - Cincinnati OH, US
David Jones - Milford OH, US
Jeffrey Gray - Loveland OH, US
Matthew Pokross - Loveland OH, US
Kevin Peters - Loveland OH, US
Artem Evdokimov - Loveland OH, US
International Classification:
A61K031/4709
C07D041/02
US Classification:
514310000, 546146000
Abstract:
Compounds of formula (I): are effective in the treatment of protein tyrosine phosphatase (PTPase) mediated disorder such as diabetes.
Matthew E Pokross from Yardley, PA, age ~48 Get Report