Inventors:
Moorthy S. S. Palanki - Encinitas CA
Shripad S. Bhagwat - San Diego CA
Hiroshi Sato - Omiya, JP
Paul E. Erdman - San Diego CA
Mary Doubleday - Doylestown PA
Assignee:
Nippon Kayaku Co., Ltd. - Tokyo
International Classification:
A61K 315377
US Classification:
5142372, 51425218, 514275, 514318, 514332, 514340, 514341, 514354, 514355, 514336, 514338, 514343, 514314, 514339, 514342, 544124, 544129, 544297, 544360, 546314, 546315, 546262, 546285, 546193, 546172, 5462697, 5462847, 5462804, 5462774, 5462731, 5462764, 5462791, 5462727, 5462681
Abstract:
Neuroprotective agents are disclosed having the following structure: wherein R , R , R , R and R are as defined herein. Such compounds have utility in the treatment of conditions which benefit from administration of neuroprotective agents generally, including treatment of central and peripheral nervous condition as well as for promoting nerve cell differentiation. Methods of treating such conditions are also disclosed, as are pharmaceutical compositions containing one or more of the compounds of this invention.