US Patent:
20070190029, Aug 16, 2007
Inventors:
Drew Pardoll - Brookeville MD, US
Richard Schulick - Baltimore MD, US
Keith Bahjat - Concord CA, US
Dirk Brockstedt - Oakland CA, US
Thomas Dubensky - Piedmont CA, US
Martin Giedlin - Moraga CA, US
Kiyoshi Yoshimura - Baltimore MD, US
Ajay Jain - Baltimore MD, US
Assignee:
Cerus Corporation - Concord CA
The Johns Hopkins University - Baltimore MD
International Classification:
A61K 48/00
A61K 39/02
C12N 1/21
US Classification:
424093200, 424200100, 435252300
Abstract:
Provided are reagents and methods for administering an attenuated bacterium for use in treating a cancerous or infectious condition. Reagents and methods for administering an attenuated bacterium for use in inducing an immune response against a tumor, cancer cell, or infective agent are further provided. Also provided are methods of diagnosis and kits.