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Maria L Zapp

from Falmouth, MA
Age ~66
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Also known as:
Maria Dr Zapp, Maria J Zapp, Maria L Zape, Marial Zapp
Related to:
Marisa Gehrig, 29Leslie Curry, 72Robert Curry, 68Joseph Gehrig, 35Matthew Gehrig, 32
Connected to:
Mary A Zapp, 68Stephen A Zapp, 36Tara J Zapp, 38Vicki L Zapp, 74Andrew M Zappa, 39Anthony M Zappa, 67Jaime K Zappa, 35Jeff A Zappa, 39Joseph R Zappa, 83Katell G Zappa, 54

Maria Zapp Phones & Addresses

  • Falmouth, MA
  • Somerville, MA
  • Houston, TX
  • 368 Green St, Boylston, MA 01505
  • Indianola, PA
  • Clinton, MA

Publications

Us Patents

Small Molecule Inhibition Of Rna/Ligand Binding

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US Patent:
59357762, Aug 10, 1999
Filed:
Mar 2, 1995
Appl. No.:
8/399378
Inventors:
Michael R. Green - Boylston MA
Maria L. Zapp - Boylston MA
Assignee:
University of Massachusetts Medical Center - Worcester MA
International Classification:
C12Q 170
C12Q 168
A01N 4308
A61K 3134
US Classification:
435 5
Abstract:
Disclosed is a method for the inhibition of binding of a ligand to an RNA, the inhibition being mediated by a small organic molecule that binds to the RNA, thereby inhibiting ligand binding. A preferred class of small organic molecules are compounds exemplified by 2,5-Bis�4-(2-N,N-dimethylaminopropylamidino)phenyl!furan.

2-Deoxystreptamine Aminoglycoside Inhibition Of Hiv Rre/Rev Binding

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US Patent:
55344089, Jul 9, 1996
Filed:
Sep 24, 1993
Appl. No.:
8/126236
Inventors:
Michael R. Green - Boylston MA
Maria L. Zapp - Boylston MA
Seth Stern - Sterling MA
Assignee:
University Of Massachusetts Medical Center - Worcester MA
International Classification:
C12Q 170
C12Q 168
US Classification:
435 5
Abstract:
Disclosed is a method for the inhibition of binding of a ligand to an RNA, the inhibition being mediated by a small organic molecule which binds to the RNA, thereby inhibiting ligand binding. A preferred class of small organic molecules are the 2-deoxystreptamine (2-DOS) aminoglycosides. Disclosed herein are members of the 2-DOS class that are useful for the inhibition of binding of Rev to an RNA containing an RRE. In an HIV infected cell, a consequence of the inhibition of the ability of Rev to bind to the RRE in HIV encoded transcripts is inhibition of HIV replication.
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Maria L Zapp from Falmouth, MA, age ~66 Get Report