Inventors:
Tongtong Wang - Medina WA
Chaitanya S. Bangur - Seattle WA
Michael J. Lodes - Seattle WA
Gary R. Fanger - Mill Creek WA
Thomas S. Vedvick - Federal Way WA
Darrick Carter - Seattle WA
Marc W. Retter - Carnation WA
Jane Mannion - Edmonds WA
Liqun Fan - Bellevue WA
Assignee:
Corixa Corporation - Seattle WA
International Classification:
C07K 14435
Abstract:
Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.