US Patent:
20110178042, Jul 21, 2011
Inventors:
Matthew F. Brown - Groton CT, US
Charles F. Donovan - Colchester CT, US
Edmund L. Eilsworth - Kalamazoo MI, US
Denton W. Hoyer - Niantic CT, US
Timothy A. Johnson - Richland MI, US
Manjinder S. Lall - Groton CT, US
Sean T. Murphy - San Diego CA, US
Debra A. Sherry - Chelsea MI, US
Clarke B. Taylor - Ann Arbor MI, US
Joseph S. Warmus - Groton CT, US
Assignee:
Pfizer Inc. - New York NY
International Classification:
A61K 31/165
C07C 233/16
C07D 233/64
C07D 213/06
C07D 307/36
C07D 261/08
C07D 239/26
C07D 249/04
C07D 277/24
A61P 31/04
A61K 31/4164
A61K 31/4406
A61K 31/341
A61K 31/42
A61K 31/4192
A61K 31/426
C07D 471/04
A61K 31/437
C07F 9/653
A61K 31/675
C07D 413/06
A61K 31/5377
US Classification:
514 92, 564171, 5483381, 546337, 549496, 548247, 544335, 548255, 548204, 514256, 514622, 514400, 514357, 514471, 514378, 514359, 514365, 546121, 514300, 548119, 544137, 5142368
Abstract:
The invention relates to a compound of formula (I): or a pharmaceutically acceptable salt thereof, thereof, wherein: G is a group of formula (II); and pharmaceutically acceptable salts, prodrugs, hydrates, or solvates, thereof, wherein A, B. L-LA, B, R-Rand m are as defined herein. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and their use in treating a bacterial infection.