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Malaz A Abutarif

from Monmouth Junction, NJ
Age ~50

Malaz Abutarif Phones & Addresses

  • 3 Raphael Dr, Monmouth Junction, NJ 08852
  • Monmouth Jct, NJ
  • 1620 Avenue I, Brooklyn, NY 11230
  • North Brunswick, NJ
  • 1 John F Kennedy Blvd, Franklin Township, NJ 08873
  • Somerset, NJ
  • Middlesex, NJ
  • N Brunswick, NJ
  • 1 John F Kennedy Blvd APT 15A, Somerset, NJ 08873

Publications

Us Patents

Methods Of Treatment Using Intravenous Formulations Comprising Temozolomide

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US Patent:
20100210700, Aug 19, 2010
Filed:
May 7, 2008
Appl. No.:
12/598012
Inventors:
Malaz Abutarif - North Brunswick NJ, US
Paul Statkevich - Raritan NJ, US
International Classification:
A61K 31/4188
A61P 35/00
US Classification:
514393
Abstract:
This invention relates to methods and drug products for treating proliferative disorders using intravenous formulations comprising temozolomide over a specific infusion time. These methods and drug products are particularly well-suited for patients who cannot swallow oral formulations. These methods and drug products also afford an added convenience to patients who are already receiving other therapeutic treatments.

Phenylephrine Pharmaceutical Formulations And Compositions For Colonic Absorption

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US Patent:
20080020055, Jan 24, 2008
Filed:
Jun 1, 2007
Appl. No.:
11/756881
Inventors:
David Monteith - Pittstown NJ, US
John O'Mullane - Mountain Lakes NJ, US
Joseph Reo - Lakeland TN, US
Robert Nowak - New Providence NJ, US
Jiansheng Wan - Springfield NJ, US
Mohammed Kabir - Lakeland TN, US
Malaz Abutarif - North Brunswick NJ, US
Glenn Fritz - Arlington TN, US
International Classification:
A61K 31/137
A61K 31/4545
A61K 9/14
A61P 11/02
A61P 31/16
A61P 37/00
US Classification:
424497000, 424490000, 514290000, 514653000
Abstract:
The invention discloses a pharmaceutical composition comprising phenylephrine or a pharmaceutically acceptable salt thereof and an erodible layer which is for oral administration wherein the composition delivers phenylephrine or a pharmaceutically acceptable salt thereof via absorption in the colon. The pharmaceutical composition comprises a core comprising phenylephrine or a pharmaceutically acceptable salt thereof and an erodible layer which is in a time-dependent, pH-dependent, or colon-specific enzyme-dependent erodible layer that degrades to expose the core to release phenylephrine in the colon. In one preferred embodiment, the erodible layer encases the core. The composition optionally further comprises phenylephrine in the erodible layer or other additional layer(s). The pharmaceutical composition can further comprise one or more additional therapeutically active agents selected from one or more of the group consisting of antihistamines, analgesics, anti-pyretics, and non-steroidal anti-inflammatory agents. The invention also discloses methods of administering phenylephrine via the colon, thereby increasing the bioavailable amount of therapeutically active unconjugated phenylephrine relative to the total phenylephrine in the plasma.

Phenylephrine Pharmaceutical Formulations And Compositions For Colonic Abosorption

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US Patent:
20150290147, Oct 15, 2015
Filed:
Dec 16, 2014
Appl. No.:
14/571890
Inventors:
- Memphis TN, US
John O'Mullane - Mountain Lakes NJ, US
Robert T. Nowak - New Providence NJ, US
Jiansheng Wan - Springfield NJ, US
Mohammed A. Kabir - Lakeland TN, US
Joseph P. Reo - Lakeland TN, US
Malaz A. Abutarif - North Brunswick NJ, US
Glenn E. Fritz - Arlington TN, US
Assignee:
MSD Consumer Care, Inc. - Memphis TN
International Classification:
A61K 31/137
A61K 47/12
A61K 31/4545
A61K 47/38
A61K 9/50
A61K 9/16
Abstract:
The invention discloses a pharmaceutical composition comprising phenylephrine or a pharmaceutically acceptable salt thereof and an erodible layer which is for oral administration wherein the composition delivers phenylephrine or a pharmaceutically acceptable salt thereof via absorption in the colon. The pharmaceutical composition comprises a core comprising phenylephrine or a pharmaceutically acceptable salt thereof and an erodible layer which is in a time-dependent, pH-dependent, or colon-specific enzyme-dependent erodible layer that degrades to expose the core to release phenylephrine in the colon. In one preferred embodiment, the erodible layer encases the core. The composition optionally further comprises phenylephrine in the erodible layer or other additional layer(s). The pharmaceutical composition can further comprise one or more additional therapeutically active agents selected from one or more of the group consisting of antihistamines, analgesics, anti-pyretics, and non-steroidal anti-inflammatory agents. The invention also discloses methods of administering phenylephrine via the colon, thereby increasing the bioavailable amount of therapeutically active unconjugated phenylephrine relative to the total phenylephrine in the plasma.
Malaz A Abutarif from Monmouth Junction, NJ, age ~50 Get Report