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Maher N Qabar

from Sammamish, WA
Age ~58

Maher Qabar Phones & Addresses

  • 518 237Th Ave, Sammamish, WA 98074 (425) 837-8769 (425) 749-6597
  • 23420 28Th St, Sammamish, WA 98074 (425) 836-9126
  • 22626 Inglewood Hill Rd, Sammamish, WA 98074 (425) 836-3448
  • Redmond, WA
  • Bothell, WA
  • Burlington, MA
  • Kiona, WA

Resumes

Resumes

Maher Qabar Photo 1

Experienced Organic/Medicinal Chemist

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Location:
Greater Seattle Area
Industry:
Biotechnology
Work:
Saltigo Jan 2010 - Jun 2012
Senior Scientist/Chemistry

CEPTYR, Inc. May 2004 - Dec 2008
Senior Scientist

Aurigene Discovery Technologies Nov 2002 - May 2004
Senior Science Fellow

Molecumetics Aug 1992 - Aug 2002
Senior Research Chemist/Group Leader

University of Illinois at Chicago Sep 1991 - Aug 1992
Post Doctoral Fellow
Education:
Wayne State University 1987 - 1991
PhD, Organic Chemistry

Publications

Us Patents

-Sheet Mimetics And Methods Relating To The Use Thereof

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US Patent:
6372744, Apr 16, 2002
Filed:
Feb 9, 2000
Appl. No.:
09/501052
Inventors:
Maher N. Qabar - Redmond WA
Michael K. McMillan - Bellevue WA
Michael S. Kahn - Kirkland WA
John E. Tulinsky - Seattle WA
Cyprian O. Ogbu - Bellevue WA
Jessymol Mathew - Bellevue WA
Assignee:
Molecumetics Ltd. - Bellevue WA
International Classification:
A61K 315025
US Classification:
514248, 514384, 530323, 530332, 5482634
Abstract:
-sheet mimetics and methods relating to the same are disclosed. The -sheet mimetics have utility as protease and kinase inhibitors, as well as inhibitors of transcription factors and protein-protein binding interactions. Methods of the invention include administration of a -sheet mimetic, or use of the same for the manufacture of a medicament for treatment of a variety of conditions associated with the targeted protease, kinase, transcription factor and/or protein-protein binding interaction.

Reverse-Turn Mimetics And Compositions And Methods Relating Thereto

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US Patent:
7345040, Mar 18, 2008
Filed:
Apr 18, 2005
Appl. No.:
11/108267
Inventors:
Maher N. Qabar - Sammamish WA, US
Marcin Stasiak - Seattle WA, US
Jessymol Mathew - Raleigh NC, US
Thomas Little - Redmond WA, US
Danwen Huang - Sammamish WA, US
Assignee:
Myriad Genetics, Inc. - Salt Lake City UT
International Classification:
A61K 31/5025
C07D 471/04
C07D 487/04
US Classification:
514249, 544279
Abstract:
Reverse-turn mimetics and methods relating to the same having the following structure are disclosed:.

Protein Tyrosine Phosphatase Inhibitors And Methods Of Use Thereof

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US Patent:
7504389, Mar 17, 2009
Filed:
Nov 15, 2005
Appl. No.:
11/280724
Inventors:
Mark Arnold Thomas Blaskovich - Bardon, AU
Ted Baughman - Bothell WA, US
Thomas Little - Redmond WA, US
William Patt - Lawrence KS, US
Maher Qabar - Sammamish WA, US
Lauri Mario Schultz - Batavia IL, US
Gangadhar Nagula - Bothell WA, US
Jennifer Lynn Gage - Kenmore WA, US
James Jeffry Howbert - Bellevue WA, US
Assignee:
Ceptyr, Inc. - Redmond WA
International Classification:
A61K 31/66
C07F 9/02
US Classification:
514114, 558190, 558 89
Abstract:
The present invention provides compounds of Formula (I) and Formula (II) that are useful for modulating the biological activity of the protein tyrosine phosphatase-1b (PTP1B) enzyme. Compounds of this invention can be used to treat diseases and/or conditions in which the PTP1B enzyme is a factor. Such diseases and/or conditions include, but are not limited to, Type 1 diabetes, Type 2 diabetes, inadequate glucose tolerance, insulin resistance, obesity, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, low HDL levels, atherosclerosis, vascular restenosis, inflammatory bowel disease, pancreatitis, adipose cell tumors, adipose cell carcinoma, liposarcoma, dyslipidemia, cancer, and neurodegenerative diseases.

Protein Tyrosine Phosphatase Inhibitors And Methods Of Use Thereof

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US Patent:
7829737, Nov 9, 2010
Filed:
Mar 6, 2008
Appl. No.:
12/043872
Inventors:
Mark Arnold Thomas Blaskovich - Bardon, AU
Ted Baughman - Bothell WA, US
Thomas Little - Redmond WA, US
Maher Qabar - Sammamish WA, US
Lauri Marie Schultz - Batavia WA, US
Feng Hong - Bellevue WA, US
William Patt - Lawrence KS, US
Gangadhar Nagula - Bothell WA, US
Jennifer Lynn Gage - Kenmore WA, US
James Jeffry Howbert - Bellevue WA, US
Assignee:
Ceptyr, Inc. - Bothell WA
International Classification:
C07F 9/02
US Classification:
558190, 558 89
Abstract:
The present invention provides compounds of Formula (I) and Formula (II) that are useful for modulating the biological activity of the protein tyrosine phosphatase-1b (PTP1B) enzyme. Compounds of this invention can be used to treat diseases and/or conditions in which the PTP1B enzyme is a factor. Such diseases and/or conditions include, but are not limited to, Type 1 diabetes, Type 2 diabetes, inadequate glucose tolerance, insulin resistance, obesity, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, low HDL levels, atherosclerosis, vascular restenosis, inflammatory bowel disease, pancreatitis, adipose cell tumors, adipose cell carcinoma, liposarcoma, dyslipidemia, cancer, and neurodegenerative diseases.

Beta-Sheet Mimetics And Methods Relating To The Use Thereof

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US Patent:
20030027819, Feb 6, 2003
Filed:
Sep 21, 2001
Appl. No.:
09/960864
Inventors:
Maher Qabar - Redmond WA, US
Michael McMillan - Bellevue WA, US
Michael Kahn - Kirkland WA, US
John Tulinsky - Seattle WA, US
Cyprian Ogbu - Bellevue WA, US
Jessymol Mathew - Bellevue WA, US
Assignee:
Molecumetics Ltd. - Bellevue WA
International Classification:
A61K031/542
A61K031/5383
A61K031/4745
A61K031/429
A61K031/424
US Classification:
514/224200, 514/229500, 514/299000, 514/367000, 514/373000, 514/412000, 514/434000, 514/456000, 514/469000
Abstract:
-sheet mimetics and methods relating to the same are disclosed. The -sheet mimetics have utility as protease and kinase inhibitors, as well as inhibitors of transcription factors and protein-protein binding interactions. Methods of the invention include administration of a -sheet mimetic, or use of the same for the manufacture of a medicament for treatment of a variety of conditions associated with the targeted protease, kinase, transcription factor and/or protein-protein binding interaction.

Beta-Sheet Mimetics And Methods Relating To The Use Thereof

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US Patent:
20060293372, Dec 28, 2006
Filed:
Feb 5, 2004
Appl. No.:
10/774043
Inventors:
Maher Qabar - Redmond WA, US
Michael McMillan - Bellevue WA, US
Michael Kahn - Kirkland WA, US
John Tulinsky - Seattle WA, US
Cyprian Ogbu - Bellevue WA, US
Jessymol Mathew - Bellevue WA, US
Assignee:
Myriad Genetics, Inc. - Salt Lake City UT
International Classification:
A61K 31/43
A61K 31/424
A61K 31/4196
US Classification:
514366000, 514375000, 514383000
Abstract:
β-sheet mimetics and methods relating to the same are disclosed. The β-sheet mimetics have utility as protease and kinase inhibitors, as well as inhibitors of transcription factors and protein-protein binding interactions. Methods of the invention include administration of a β-sheet mimetic, or use of the same for the manufacture of a medicament for treatment of a variety of conditions associated with the targeted protease, kinase, transcription factor and/or protein-protein binding interaction.

Protein Tyrosine Phosphatase Inhibitors And Methods Of Use Thereof

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US Patent:
20090131374, May 21, 2009
Filed:
Jan 30, 2009
Appl. No.:
12/363422
Inventors:
Mark Arnold Thomas Blaskovich - Bardon, AU
Ted Baughman - Bothell WA, US
Thomas Little - Redmond WA, US
William Patt - Lawrence KS, US
Maher Qabar - Sammamish WA, US
Lauri Marie Schultz - Batavia WA, US
Feng Hong - Bellevue WA, US
Gangadhar Nagula - Bothell WA, US
Jennifer Lynn Gage - Kenmore WA, US
James Jeffry Howbert - Bellevue WA, US
Assignee:
CEPTYR, INC. - Redmond WA
International Classification:
A61K 31/662
A61P 3/10
US Classification:
514117, 514120
Abstract:
The present invention provides compounds of Formula (I) and Formula (II) that are useful for modulating the biological activity of the protein tyrosine phosphatase-1b (PTP1B) enzyme. Compounds of this invention can be used to treat diseases and/or conditions in which the PTP1B enzyme is a factor. Such diseases and/or conditions include, but are not limited to, Type 1 diabetes, Type 2 diabetes, inadequate glucose tolerance, insulin resistance, obesity, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, low HDL levels, atherosclerosis, vascular restenosis, inflammatory bowel disease, pancreatitis, adipose cell tumors, adipose cell carcinoma, liposarcoma, dyslipidemia, cancer, and neurodegenerative diseases.

Methods For Regulating Transcription Factors

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US Patent:
61178969, Sep 12, 2000
Filed:
Feb 12, 1998
Appl. No.:
9/022934
Inventors:
Maher N. Qabar - Redmond WA
Michael K. McMillan - Bellevue WA
Michael S. Kahn - Kirkland WA
John E. Tulinsky - Seattle WA
Cyprian O. Ogbu - Bellevue WA
Jessymol Mathew - Bellevue WA
Assignee:
Molecumetics Ltd. - Bellevue WA
International Classification:
A61K 3141
C07K 500
C07K 700
C07K 1600
C07D24912
US Classification:
514384
Abstract:
beta. -sheet mimetics and methods relating to the same are disclosed. The. beta. -sheet mimetics have utility as protease and kinase inhibitors, as well as inhibitors of transcription factors and protein-protein binding interactions. Methods of the invention include administration of a. beta. -sheet mimetic, or use of the same for the manufacture of a medicament for treatment of a variety of conditions associated with the targeted protease, kinase, transcription factor and/or protein-protein binding interaction.
Maher N Qabar from Sammamish, WA, age ~58 Get Report