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Mahavir Prashad

from Montville, NJ

Mahavir Prashad Phones & Addresses

  • 27 Davenport Rd, Montville, NJ 07045 (973) 263-5872 (973) 670-5301
  • 228 W End Ave, Hopatcong, NJ 07843 (973) 770-2359
  • 312 Quaker Church Rd #B19, Randolph, NJ 07869 (973) 361-9667
  • 27 Davenport Rd, Montville, NJ 07045 (973) 670-5301

Work

Position: Farming-Forestry Occupation

Education

Degree: Associate degree or higher

Emails

Publications

Us Patents

Process For Preparing 5,6-Diethyl-2,3-Dihydro-1H-Inden-2-Amine

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US Patent:
6933410, Aug 23, 2005
Filed:
Feb 14, 2003
Appl. No.:
10/367402
Inventors:
Mahavir Prashad - Montville NJ, US
Bin Hu - North Plainfield NJ, US
Olivier Lohse - Belfort, FR
Assignee:
Novartis AG - Basel
International Classification:
C07C209/44
US Classification:
564414, 564428
Abstract:
A process for preparing 5,6-diethyl-2,3-dihydro-1H-inden-2-amine and acid addition salts thereof from 2-aminoindan. The process comprises protecting the amino group of 2-aminoindan, acetylating the ring in the protected compound, reducing the acetyl group to ethyl to form a monoethyl derivative, acetylating the monoethyl derivative, reducing the acetyl group to form a diethyl derivative, deprotecting the latter by hydrolysis and recovering the product in free or salt form. The process does not use deleterious Grignard reagents or nitrites such as isoamyl nitrite, and provides high regioselectivity and high yield of 5,6-diethyl-2,3-dihydro-1H-inden-2-amine. In addition, the process uses acetyl halide as both a reactant and a solvent.

Chemical Process For The Preparation Of Intermediates To Obtain -Formyl Hydroxy-Lamine Compounds

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US Patent:
7452999, Nov 18, 2008
Filed:
Feb 20, 2004
Appl. No.:
10/544919
Inventors:
Mahavir Prashad - Montville NJ, US
Bin Hu - Green Brook NJ, US
Joel Slade - Flanders NJ, US
Prasad Koteswara Kapa - Parsippany NJ, US
Michael John Girgis - Montville NJ, US
Assignee:
Novartis AG - Basel
International Classification:
C07D 417/00
C07D 401/00
C07D 277/00
C07D 207/00
C07D 405/00
C07D 317/44
US Classification:
548200, 548518, 548526, 5462697, 5462784, 5462791, 549439
Abstract:
Improved processes for preparing intermediates useful for preparing antibacterial N-[1-oxo-2-alkyl-3-(N-hydroxyformamido)-propyl}-(carbonylamino-aryl or -heteroaryl)-azacyclo4-7alkanes or thiazacyclo4-7alkanes, which have one or more of the following features: (1) make use of a particular β-lactam intermediate; (2) which make use of a particular resolving agents, enantiomerically pure substituted propionic acids, especially (R)-2-butyl-3-hydroxy-propionic acid; (3) which avoid the use of hydrogen peroxide; and (4) which facilitate selective debenzylation reducing production of waste by-products.

Process For Preparing N-Hydroxyformamido-Propyl Pyrrolidin Compounds And Intermediates

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US Patent:
7589216, Sep 15, 2009
Filed:
Sep 18, 2003
Appl. No.:
10/527628
Inventors:
Prasad Koteswara Kapa - Parsippany NJ, US
Xinglong Jiang - Hillsborough NJ, US
Eric M. Loeser - Scotch Plains NJ, US
Joel Slade - Flanders NJ, US
Mahavir Prashad - Montville NJ, US
George Tien-San Lee - Towaco NJ, US
Assignee:
Novartis AG - Basel
International Classification:
C07D 277/04
C07D 207/16
US Classification:
548537, 548540, 548200, 537533, 5462791, 514340
Abstract:
The present invention is directed to a process for preparing intermediates that are useful to prepare certain antibacterial N-formyl hydroxylamine compounds which are peptide deformylase inhibitors. The process makes use α β-lactarn intermediate. Certain optically pure intermediates are also claimed.

Process For The Synthesis Of Organic Compounds

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US Patent:
7781597, Aug 24, 2010
Filed:
Jun 7, 2006
Appl. No.:
11/915691
Inventors:
Stephan Abel - Weil am Rhein, DE
Murat Acemoglu - Basel, CH
Bernhard Erb - Gipf-Oberfrick, CH
Christoph Krell - Basel, CH
Joseph Sclafani - Ledgewood NJ, US
Mark Meisenbach - Durmenach, FR
Mahavir Prashad - Montville NJ, US
Wen-Chung Shieh - Berkeley Heights NJ, US
Song Xue - Parsippany NJ, US
Assignee:
Novartis AG - Basel
International Classification:
C07D 233/56
US Classification:
5483435
Abstract:
The present invention provides an efficient, safe and cost effective way to prepare 5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzenamine which is a key intermediate for the preparation of substituted pyrimidinylaminobenzamides of formula (II):.

Fused Pyridine Derivatives For Use As Vanilloid Receptor Antagonists For Treating Pain

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US Patent:
7915264, Mar 29, 2011
Filed:
Mar 25, 2002
Appl. No.:
10/469756
Inventors:
Andrew James Culshaw - London, GB
Peter Gull - Pfeffingen, CH
Allan Hallett - London, GB
Max Peter Seiler - Riehen, CH
Kaspar Zimmermann - Oberwil, CH
Yugang Liu - Bridgewater NJ, US
Mahavir Prashad - Montville NJ, US
Assignee:
Novartis AG - Basel
International Classification:
A61K 31/519
C07D 471/04
US Classification:
514258, 544279
Abstract:
The invention provides compounds of formula (I) wherein R, R, R, R, and Rare as defined in the description, and the preparation thereof. The compounds of formula (I) are useful as pharmaceuticals.

Organic Compounds And Their Uses

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US Patent:
8008263, Aug 30, 2011
Filed:
Oct 10, 2008
Appl. No.:
12/249186
Inventors:
Shawn D. Britt - Andover MA, US
Lech Andrzej Ciszewski - Morristown NJ, US
Jiping Fu - Arlington MA, US
Subramanian Karur - Arlington MA, US
Yugang Liu - Bridgewater NJ, US
Peichao Lu - Malden MA, US
David Thomas Parker - Lexington MA, US
Mahavir Prashad - Montville NJ, US
Prakash Raman - Acton MA, US
Pascal Rigollier - Mulhouse, FR
Mohindra Seepersaud - Acton MA, US
Aregahegn Yifru - Somerville MA, US
Rui Zheng - Waltham MA, US
Assignee:
Novartis AG - Basel
International Classification:
A61K 38/07
A61K 38/55
US Classification:
514 219, 514 37, 514 201, 514 203, 530330
Abstract:
The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.

Process For The Synthesis Of Organic Compounds

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US Patent:
8008504, Aug 30, 2011
Filed:
Jul 12, 2010
Appl. No.:
12/834295
Inventors:
Stephan Abel - Weil Am Rhein, DE
Murat Acemoglu - Basel, CH
Bernhard Erb - Gipf-Oberfrick, CH
Christoph Krell - Basel, CH
Joseph Sclafani - Ledgewood NJ, US
Mark Meisenbach - Durmenach, FR
Mahavir Prashad - Montville NJ, US
Wen-Chung Shieh - Berkeley Heights NJ, US
Song Xue - Parsippany NJ, US
Assignee:
Novartis AG - Basel
International Classification:
C07D 233/56
C07C 205/12
US Classification:
5483435, 568938
Abstract:
The present invention provides an efficient, safe and cost effective way to prepare 5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzenamine which is a key intermediate for the preparation of substituted pyrimidinylaminobenzamides of formula (II):.

Organic Compounds

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US Patent:
8258128, Sep 4, 2012
Filed:
Feb 21, 2007
Appl. No.:
12/224734
Inventors:
Pietro Bollinger - Bottmingen, CH
Mahavir Prashad - Montville NJ, US
Bernhard Riss - Hunigue, FR
Janet Dawson King - Bennwil, CH
Peter C. Hiestand - Allschwil, CH
Yugang Liu - Bridgewater NJ, US
Jonathan King - Bennwil, CH
Vincent Schmid - Domdidier, CH
Friedrich Schuerch - Frenkendorf, CH
Assignee:
Novartis AG - Basel
International Classification:
A61K 31/33
A61K 31/55
A61K 31/38
A01N 43/00
A01N 43/12
US Classification:
51421301, 514215, 514217, 514438, 514443
Abstract:
The present invention relates to novel aza-thia-benzoazulene derivatives of formula I as defined in the claims, their preparation, the use of these novel compounds for the preparation of pharmaceutical compositions, the use of these novel compounds and compositions for managing arthritis and arthritis-related conditions as well as in the treatment of pain in animals and humans. More particularly, the present invention relates to pharmaceutical, preferably veterinary compositions and methods for reducing inflammation and pain associated with acute inflammation of body parts, particularly joints, due to injury or due to arthritic conditions or other disease conditions.
Mahavir Prashad from Montville, NJ Get Report