Inventors:
Celia A. SCHIFFER - Shrewsbury MA, US
Madhavi NALAM - Worcester MA, US
Inge DIERYNCK - Berchem, BE
Annick Ann PEETERS - Wilrijk, BE
Tim Hugo JONKERS - Edegem, BE
Assignee:
UNIVERSITY OF MASSACHUSETTS - Boston MA
TIBOTEC PHARMACEUTICALS LTD - Co. Cork
International Classification:
C12N 9/96
G06G 7/48
Abstract:
Described herein are methods for rational design of inhibitors of HIV-1 protease, and crystal structures of HIV-1 protease inhibitors bound to HIV-1 protease.