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Lutz B Giebel

from Newbury, NH
Age ~64
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Also known as:
Lutz Christine Giebel, Raymond Kevin O'Hara, Raymond K O'Hara, Z Giebel
Related to:
Cindy L O'Hara, 58
Connected to:
Bonnie G Giebel, 71Buddy Giebel, 94Chris L Giebel, 69Dan W Giebel, 62Faith Z Giebel, 67Christopher L Giebels, 61Gary L Giebelstein, 61Erin M Giebert, 54Matthew H Giebitz, 40Johnny K Giebler, 64

Lutz Giebel Phones & Addresses

  • Newbury, NH
  • 442 Nevada Ave, San Mateo, CA 94402 (650) 678-9922
  • Glen Ellen, CA
  • Madison, WI
  • Burlingame, CA
  • 442 Nevada Ave, San Mateo, CA 94402

Resumes

Resumes

Lutz Giebel Photo 1

Biotech Entrepreneur

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Location:
San Mateo, CA
Industry:
Biotechnology
Work:
Tbd
Biotech Entrepreneur
Education:
University of Wisconsin - Madison
Heidelberg University
Doctorates, Doctor of Philosophy, Genetics, Philosophy
Languages:
German
English
Lutz Giebel Photo 2

Lutz Giebel

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Business Records

Name / Title
Company / Classification
Phones & Addresses
Lutz B. Giebel
President
Cart Proteomics Inc
Management Consulting Services
344 Virginia Ave, San Mateo, CA 94402
(650) 685-8843
Lutz B. Giebel
Managing
Didyma, LLC
Business Consulting · Business Services at Non-Commercial Site
344 Virginia Ave, San Mateo, CA 94402

Publications

Us Patents

Transgenic Mammals Lacking Expression Of Erythropoietin Or Of Erythropoietin Receptor, Transgenic Mammals Expressing Chimeric Erythropoietin Receptors, Constructs For Producing The Transgenic Mammals And Uses Therefor

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US Patent:
6485964, Nov 26, 2002
Filed:
Apr 15, 1997
Appl. No.:
08/839605
Inventors:
Hong Wu - Brookline MA
Xin Liu - Brookline MA
Harvey F. Lodish - Brookline MA
Lutz B. Giebel - San Mateo CA
Michael J. Ross - Hillsborough CA
David Matthews - San Francisco CA
Assignee:
Arris Pharmaceutical Corporation - South San Francisco CA
Whitehead Institute for Biomedical Research - Cambridge MA
International Classification:
C12N 1500
US Classification:
4353201, 536 231, 800 18, 800 25
Abstract:
Transgenic nonhuman mammals, such as transgenic mice, which lack erythropoietin expression, in which the erythropoietin receptor is deleted, which carry a heterologous erythropoietin receptor (e. g. , a chimeric receptor); constructs useful for producing such transgenic nonhuman mammals, embryonic stem cells containing the constructs, a method of producing the transgenic nonhuman mammals and a method of identifying erythropoietin mimics or mimetics.

Transgenic Mammals Lacking Expression Of Erythropoietin Or Of Erythropoietin Receptor, Transgenic Mammals Expressing Chimeric Erythropoietin Receptors, Constructs For Producing The Transgenic Mammals And Uses Therefor

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US Patent:
20030177515, Sep 18, 2003
Filed:
Oct 8, 2002
Appl. No.:
10/267923
Inventors:
Hong Wu - Brookline MA, US
Xin Liu - Brookline MA, US
Harvey Lodish - Brookline MA, US
Lutz Giebel - San Mateo CA, US
Michael Ross - Hillsborough CA, US
David Matthews - San Francisco CA, US
Assignee:
Arris Pharmaceutical Corporation - South San Francisco CA
International Classification:
A01K067/027
C07H021/04
C12P021/02
C12N005/06
C07K014/72
US Classification:
800/018000, 435/069100, 435/320100, 435/354000, 536/023500, 530/350000
Abstract:
Transgenic nonhuman mammals, such as transgenic mice, which lack erythropoietin expression, in which the erythropoietin receptor is deleted, which carry a heterologous erythropoietin receptor (e.g., a chimeric receptor); constructs useful for producing such transgenic nonhuman mammals, embryonic stem cells containing the constructs, a method of producing the transgenic nonhuman mammals and a method of identifying erythropoietin mimics or mimetics.

Pilot Apparatus For Peptide Synthesis And Screening

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US Patent:
55852750, Dec 17, 1996
Filed:
Jun 18, 1993
Appl. No.:
8/079741
Inventors:
Derek Hudson - San Anselmo CA
Charles R. Johnson - Berkeley CA
Lutz Giebel - Burlingame CA
Assignee:
Arris Pharmaceutical Corporation - South San Francisco CA
International Classification:
G01N 33543
C07K 1700
US Classification:
436518
Abstract:
Method and apparatus for simple and rapid preparation of reusable, addressable surface-immobilized arrays of biomolecules (libraries) used for screening for interaction with any biologically significant target. A special plate having on or in its surface a plurality of discreet functionalized substrate areas, typically in arrays of 10. times. 10 to 400. times. 400, is provided for chemical synthesis or bonding thereon of desired families of biomolecules (e. g. peptides, DNA, RNA, oligosaccharides). In the case of peptides, such as hexapeptides, the resulting permanently hexapeptide-loaded plate is a reusable Addressable Synthetic Peptide Combinatorial Library (ASPCL), in which 1 to 3 (typically two) of the positions in the sequence are uniquely identified by the address location. The preferred plate embodiment employs an HPMP wink of porous polyolefin removably received in holes in the plate. A unique multi-slot block assembly is used to prepare the ASPCLs.

Thin Film Hpmp Matrix Systems And Methods For Constructing And Displaying Ligands

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US Patent:
55762204, Nov 19, 1996
Filed:
Feb 19, 1993
Appl. No.:
8/019725
Inventors:
Derek Hudson - San Anselmo CA
Charles R. Johnson - Berkeley CA
Michael J. Ross - Hillsborough CA
Kevin R. Shoemaker - San Francisco CA
Robert T. Cass - San Mateo CA
Lutz B. Giebel - Burlingame CA
Assignee:
Arris Pharmaceutical Corporation - South San Francisco CA
International Classification:
G01N 33543
US Classification:
436518
Abstract:
The invention relates to methods and systems of unhindered construction and display of tethered organic ligand molecules, and more particularly to preparation and use of thin film, substantially non-crosslinked hydrophilic polar multi-functionalized polymers (HPMPs) anchored to a variety of functionalized substrates so that the HPMP forms a thin film matrix layer providing a unique highly hydrated, high dielectric environment equivalent to an aqueous solution, for affinity binding of Ligands (L) to Tagged Target Molecules (TTMs). Ligands, and especially MER. sub. n ligand libraries such as peptide libraries, are singly tethered to the HPMP by a "permanent" strong covalent bond so that subsequent displacement of the TTM does not also displace the ligand from the HPMP, thereby making the HPMP tethered Ligand library reusable. The HPMP thin film is on the order of 200-2000. ANG. thick, is highly accessible (to the TTMs), and permits flexible, 3-D display of the singly tethered ligands for free permeability therein of the TTMs for affinity binding.

Bivalent Molecules That Form An Activating Complex With An Erythropoietin Receptor

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US Patent:
61038792, Aug 15, 2000
Filed:
Jun 16, 1997
Appl. No.:
8/876813
Inventors:
Warak Lee Chaovapong - San Diego CA
Lutz B. Giebel - San Mateo CA
Cyrus Karkaria - Cambridge MA
Michael J. Ross - San Mateo CA
Helmut H. Schneider - San Francisco CA
Kevin Shoemaker - San Francisco CA
Assignee:
Axys Pharmaceuticals, Inc. - South San Francisco CA
International Classification:
C07K 1618
C07K 1628
C12N 512
US Classification:
5303881
Abstract:
Antibodies and Bivalent molecules which activate erythropoietins and induce the proliferation or differentiation of erythroid progenitor cells are provided. Also provided are methods of using such bivalent molecules for drug discovery, diagnosis and treatment of disorders related to the activation of an erythropoietin receptor.

Method And Apparatus For Peptide Synthesis And Screening

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US Patent:
55916465, Jan 7, 1997
Filed:
Sep 2, 1992
Appl. No.:
7/939065
Inventors:
Derek Hudson - San Anselmo CA
Charles R. Johnson - Berkeley CA
Lutz Giebel - Burlingame CA
Assignee:
Arris Pharmaceutical - San Francisco CA
International Classification:
G01N 33543
C07K 1700
US Classification:
436518
Abstract:
Method and apparatus for simple and rapid preparation of reusable, addressable surface-immobilized arrays of biomolecules (libraries) used for screening for interaction with any biologically significant target. A special plate having on its surface a plurality of discreet functionalized substrate areas, typically in arrays of 10. times. 10 to 400. times. 400, is provided for chemical synthesis or bonding thereon of desired families of biomolecules (e. g. peptides, DNA, RNA, oligosaccharides). In the case of peptides, such as hexapeptides, the resulting permanently hexapeptide-loaded plate is a reusable Addressable Synthetic Peptide Combinatorial Library (ASPCL), in which 1 to 3 (typically two) of the positions in the sequence are uniquely identified by the address location. Plate embodiments include substrates of physically bonded (e. g. glued) conventional particulate materials such as Pepsyn-K, or functionalizable films of linear or crosslinked polymers covalently attached to, or physically adhered to the plate surface.

Single-Chain Tnf Receptor 2 Agonist Fusion Proteins

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US Patent:
20200369739, Nov 26, 2020
Filed:
Jun 5, 2018
Appl. No.:
16/618233
Inventors:
- Euless TX, US
Lutz B Giebel - San Mateo CA, US
Leonard G Presta - San Francisco CA, US
Assignee:
Relinia, Inc. - Euless TX
International Classification:
C07K 14/525
A61P 29/00
Abstract:
This invention provides for a fusion protein between a single chain TNFR2 Selective Agonist protein (scTNFR2 Selective Agonist) and a dimerization domain, such as an IgGFc protein. The single chain TNFR2 Selective Agonist moiety provides a therapeutic activity by selectively activating the TNFR2 form of the TNF-α receptor, thus selectively stimulating Tregs and/or increasing myelin deposition.
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Lutz B Giebel from Newbury, NH, age ~64 Get Report