20120021928, Jan 26, 2012
Mia Olsson - Knivsta, SE
Linda Tintle - Wurtsboro NY, US
506 7, 536 2431, 536 2433, 435 612
The present invention provides genetic tests for the copy number or a duplication of an upstream element of the Hyaluronic Acid Synthase 2 (HAS2) gene on chromosome 13 in Shar-Pei dogs to assess risk for a Shar-Pei dog to develop Shar-Pei fever. As Shar-Pei fever is a serious disease, and its chronic state involves a high risk of developing systemic amyloidosis and kidney failure, a genetic test for the copy number of the duplication will be useful in Shar-Pei breeding. Also provided are probes and primer pairs for use in these methods.