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Lief E Fenno

from Austin, TX
Age ~40
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Also known as:
Lief Ericsson Fenno, Lief Carolyn Fenno, Ericsson Fenno Lief, Fenno Lief
Related to:
Bobbie J Fenno, 45
Connected to:
Christopher P Fenno, 44Christy D Fenno, 43Dencie A Fenno, 81Carolyn J Fennoy, 77Brittany Fennych, 35Amaris J Feno, 44Robert L Fenocchi, 82Ryan K Fenocchi, 40Gail A Fenochetti, 78Kelly F Fenoff, 63

Lief Fenno Phones & Addresses

  • Austin, TX
  • 2331 Princeton St, Palo Alto, CA 94306
  • Stanford, CA
  • Fairbanks, AK
  • San Francisco, CA
  • Somerville, MA

Work

Company: Deisseroth lab Sep 2008 Position: Graduate student

Education

Degree: MD/PhD School / High School: Stanford University School of Medicine 2008 to 2016 Specialities: Neuroscience

Skills

Neuroscience • Animal Models • Molecular Biology • Molecular Cloning • Fluorescence Microscopy • Research • Cell Culture • Microscopy • Immunohistochemistry • Cell Biology • Electrophysiology • Confocal Microscopy • Biochemistry • Immunofluorescence • Neurology • Psychiatry • Life Sciences

Languages

English • Spanish

Ranks

Certificate: Physician

Industries

Hospital & Health Care

Resumes

Resumes

Lief Fenno Photo 1

Instructor

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Location:
555 4Th St, San Francisco, CA 94107
Industry:
Hospital & Health Care
Work:
Deisseroth Lab since Sep 2008
Graduate Student
Stanford University School of Medicine since 2007
MD/PhD Student
Cowan Lab Jun 2007 - Jun 2008
Research Associate
Melton Lab Sep 2004 - Jun 2007
Undergraduate Research Associate
Education:
Stanford University School of Medicine 2008 - 2016
MD/PhD, Neuroscience Harvard University 2003 - 2007
BA, Neurobiology
Skills:
Neuroscience
Animal Models
Molecular Biology
Molecular Cloning
Fluorescence Microscopy
Research
Cell Culture
Microscopy
Immunohistochemistry
Cell Biology
Electrophysiology
Confocal Microscopy
Biochemistry
Immunofluorescence
Neurology
Psychiatry
Life Sciences
Languages:
English
Spanish
Certifications:
Physician

Publications

Us Patents

Optically-Controlled Cns Dysfunction

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US Patent:
20130295015, Nov 7, 2013
Filed:
Nov 4, 2011
Appl. No.:
13/882719
Inventors:
Karl Deisseroth - Stanford CA, US
Kay Tye - Cambridge MA, US
Lief Fenno - San Francisco CA, US
Assignee:
The Board of Trustees of Leland Stanford Jnior Universtiy - Palo Alto CA
International Classification:
A61K 49/00
US Classification:
424 92, 800 9, 4353201, 514 44 R, 435325
Abstract:
Provided herein are animals expressing light-responsive opsin proteins in the basal lateral amygdala of the brain and methods for producing the same wherein illumination of the light-responsive opsin proteins causes anxiety in the animal. Also provided herein are methods for alleviating and inducing anxiety in an animal as well as methods for screening for a compound that alleviates anxiety in an animal.

Stabilized Step Function Opsin Proteins And Methods Of Using The Same

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US Patent:
20130347137, Dec 26, 2013
Filed:
Nov 4, 2011
Appl. No.:
13/882666
Inventors:
Karl Deisseroth - Stanford CA, US
Ofer Yizhar - Palo Alto CA, US
Lief Fenno - San Francisco CA, US
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
G01N 33/50
US Classification:
800 9, 424 92, 514 44 R, 435325, 435 29, 4352871
Abstract:
Provided herein are compositions comprising non-human animals comprising neurons expressing stabilized step function opsin proteins on neural plasma membranes and methods of using the same to selectively depolarize neurons residing in microcircuits of the pre-frontal cortex to affect one or more social behaviors, communications, and/or conditioned behaviors in the non-human animal.

Light-Activated Chimeric Opsins And Methods Of Using The Same

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US Patent:
20130224821, Aug 29, 2013
Filed:
May 2, 2013
Appl. No.:
13/875966
Inventors:
The Board of Trustees of the Leland Stanford Junior University - , US
Ofer Yizhar - Palo Alto CA, US
Lief Fenno - San Francisco CA, US
Peter Hegemann - Falkensee, DE
Matthias Prigge - Berlin, DE
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
C07K 19/00
C12N 13/00
US Classification:
4351734, 530350, 536 234, 435325
Abstract:
Provided herein are compositions comprising light-activated chimeric proteins expressed on plasma membranes and methods of using the same to selectively depolarize excitatory or inhibitory neurons.

Compositions And Methods For Controlling Production Of Polypeptides In Cells

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US Patent:
20230064644, Mar 2, 2023
Filed:
Feb 3, 2021
Appl. No.:
17/796839
Inventors:
- Stanford CA, US
Charu Ramakrishnan - San Jose CA, US
Yoon Seok Kim - Stanford CA, US
Lief E. Fenno - Palo Alto CA, US
International Classification:
C12N 15/85
C12N 15/66
Abstract:
The present disclosure provides recombinant expression vectors for modulating production of polypeptides of interest in a target cell or target cell population. Aspects of the disclosure include recombinant expression vectors having coding sequences encoding portions of a polypeptide of interest, where the coding sequences are flanked by recombinase recognition sites. Also provided are methods for using the recombinant expression vectors as well as a device for monitoring expression of the polypeptide of interest.

Light-Activated Chimeric Opsins And Methods Of Using The Same

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US Patent:
20190241627, Aug 8, 2019
Filed:
Dec 5, 2018
Appl. No.:
16/211083
Inventors:
- Stanford CA, US
Ofer Yizhar - Palo Alto CA, US
Lief Fenno - San Francisco CA, US
Peter Hegemann - Falkensee, DE
Matthias Prigge - Berlin, DE
International Classification:
C07K 14/405
A61N 5/06
C07K 19/00
C12N 13/00
G01N 33/50
A01K 67/027
Abstract:
Provided herein are compositions comprising light-activated chimeric proteins expressed on plasma membranes and methods of using the same to selectively depolarize excitatory or inhibitory neurons.

Optically-Controlled Cns Dysfunction

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US Patent:
20180333456, Nov 22, 2018
Filed:
Apr 19, 2018
Appl. No.:
15/957608
Inventors:
- Stanford CA, US
Kay Tye - Cambridge MA, US
Lief Fenno - San Francisco CA, US
International Classification:
A61K 38/17
A01K 67/027
G01N 33/50
A61K 9/00
A61K 49/00
C07K 14/705
A61K 41/00
C12N 15/85
C12N 15/86
C12N 7/00
A61K 48/00
A61N 5/06
A61B 5/16
Abstract:
Provided herein are animals expressing light-responsive opsin proteins in the basal lateral amygdala of the brain and methods for producing the same wherein illumination of the light-responsive opsin proteins causes anxiety in the animal. Also provided herein are methods for alleviating and inducing anxiety in an animal as well as methods for screening for a compound that alleviates anxiety in an animal.

Light-Activated Chimeric Opsins And Methods Of Using The Same

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US Patent:
20180051058, Feb 22, 2018
Filed:
Nov 3, 2017
Appl. No.:
15/803472
Inventors:
- Stanford CA, US
Ofer Yizhar - Palo Alto CA, US
Lief Fenno - San Francisco CA, US
Peter Hegemann - Falkensee, DE
Matthias Prigge - Berlin, DE
International Classification:
C07K 14/405
A01K 67/027
C07K 19/00
C12N 13/00
G01N 33/50
A61N 5/06
A61K 38/00
Abstract:
Provided herein are compositions comprising light-activated chimeric proteins expressed on plasma membranes and methods of using the same to selectively depolarize excitatory or inhibitory neurons.

Stabilized Step Function Opsin Proteins And Methods Of Using The Same

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US Patent:
20160316730, Nov 3, 2016
Filed:
Jul 19, 2016
Appl. No.:
15/214400
Inventors:
- Stanford CA, US
Ofer Yizhar - Palo Alto CA, US
Lief Fenno - San Francisco CA, US
International Classification:
A01K 67/027
C12N 5/0793
G01N 33/50
C07K 14/405
Abstract:
Provided herein are compositions comprising non-human animals comprising neurons expressing stabilized step function opsin proteins on neural plasma membranes and methods of using the same to selectively depolarize neurons residing in microcircuits of the pre-frontal cortex to affect one or more social behaviors, communications, and/or conditioned behaviors in the non-human animal.
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Lief E Fenno from Austin, TX, age ~40 Get Report