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Koji Nakanishi Phones & Addresses

  • Cliffside Park, NJ
  • 560 Riverside Blvd, New York, NY 10027 (212) 663-7605 (212) 749-5935 (212) 749-7018
  • 560 Fdr Dr, New York, NY 10002 (212) 749-5935 (212) 749-7018 (212) 663-7605
  • Cambridge, MA
  • Bronx, NY
  • 560 Riverside Dr APT 9J, New York, NY 10027 (212) 663-7605

Resumes

Resumes

Koji Nakanishi Photo 1

Centennial Professor, Emeritus

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Location:
535 west 116Th St, New York, NY 10027
Work:
Collaborative Drug Discovery - Cdd Vault
Centennial Professor, Emeritus

Columbia University In the City of New York
Centennial Professor of Chemistry Emeritus
Education:
Nagoya University 1952 - 1954
Doctorates, Doctor of Philosophy, Philosophy, Chemistry
Harvard University 1950 - 1952
Nagoya University 1943 - 1947
Bachelors, Bachelor of Science, Chemistry
Skills:
Organic Synthesis
Biochemistry
Chemistry
Science
Organic Chemistry
Nmr
Molecular Biology
Hplc
Spectroscopy
Research
Mass Spectrometry
Chromatography
Uv/Vis
Protein Purification
Koji Nakanishi Photo 2

Professor

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Location:
New York, NY
Industry:
Higher Education
Work:
Columbia University In the City of New York
Professor

Publications

Us Patents

Degrading Sludge With Microorganisms Atcc 55926 Or 202050

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US Patent:
6420165, Jul 16, 2002
Filed:
May 24, 2000
Appl. No.:
09/577640
Inventors:
Bernard I. Weinstein - Engelwood NJ
David Figurski - Dumont NJ
Sadayori Hoshina - Tokyo, JP
Koji Nakanishi - New York NY
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
B09B 300
US Classification:
4352625, 4352525, 435261, 435264, 435832
Abstract:
A biologically pure culture of a microorganism is provided designated SH2A and deposited under ATCC Accession No. 55926, or a mutant derived therefrom. Further provided is a biologically pure culture of a microorganism designated SH2B and deposited under ATCC Accession No. 202050, or a mutant derived therefrom. A method of degrading an organic material such as sludge is carried out by treating the organic material with an effective, degrading amount of either SH2A or a mutant derived therefrom, or SH2B or a mutant derived therefrom. The microorganism designated SH2A or a mutant derived therefrom, or SH2B or a mutant derived therefrom, is grown by culturing the microorganism at a temperature and in a medium effective to promote growth of the microorganism.

Method For Isolating Terpene Trilactones (Ginkgolides, Bilobalide) From Leaves And Pharmaceutical Powders Of Ginkgo Biloba

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US Patent:
6590109, Jul 8, 2003
Filed:
Jul 11, 2002
Appl. No.:
10/194089
Inventors:
Dirk Lichtblau - Halle/S., DE
Nina Berova - New York NY
John Berger - Oro Valley AZ
Koji Nakanishi - New York NY
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
C07D30793
US Classification:
549297, 549298
Abstract:
A method of isolating terpene trilactones from plant material or extract comprising the steps of suspending the plant material or extract in either water or an aqueous solution of an oxidation reagent; extracting the terpene trilactones using an acceptable extraction agent; separating the organic layer from the aqueous layer; washing the organic layer with an acceptable aqueous salt or hydroxide solution, which may be an alkaline solution; and drying the organic layer to form a dried extract containing terpene trilactones. Further purification by treatment with or filtration over activated charcoal, by treatment with or filtration over alumina and by recrystallization with an acceptable solvent or solvent mixture leads to extracts with a content of terpene trilactones higher than 50%. Unwanted levels of ginkgolic acids are reduced to acceptable levels by reversed phase chromatography.

Analogs Of Terpene Trilactones From Ginkgo Biloba For Bioorganic And Imaging Studies

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US Patent:
6693091, Feb 17, 2004
Filed:
Mar 29, 2002
Appl. No.:
10/109965
Inventors:
Makiko Suehiro - White Plains NY
Koji Nakanishi - New York NY
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
A61K 3133
US Classification:
514183, 514461, 548960, 549297, 549298, 424 181, 424 185, 424 189
Abstract:
A compound having the structure: wherein R is H, OH, a photoactivatable moiety, a fluorescent moiety, or a radioactive moiety; wherein R is H, OH, a photoactivatable moiety, a fluorescent moiety, or a radioactive moiety; wherein R is H or OH; wherein R is H, OH, a photoactivatable moiety, a fluorescent moiety, or a radioactive moiety; and wherein at least one of R , R , R , or R is a photoactivatable moiety, a fluorescent moiety, or a radioactive moiety. Optically pure enantiomers and salts of the compound are also described. Also, the synthesis of the compound, and uses of the compound, such as in a method for detecting the localization of, or identifying, receptors, enzymes or other targets, whether in a cell or in a subject.

Effector Proteins Of Rapamycin

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US Patent:
6713607, Mar 30, 2004
Filed:
Sep 13, 2001
Appl. No.:
09/950634
Inventors:
Thomas J. Caggiano - Morrisville PA
Yanqiu Chen - New York NY
Amedeo A. Failli - Princeton NJ
Koji Nakanishi - New York NY
Assignee:
Wyeth - Madison NJ
International Classification:
C07K 100
US Classification:
530350
Abstract:
This invention comprises novel Rapamycin-FKBP12 binding proteins of mammalian origin for identification, design and synthesis of immunomodulatory, anti-restenosis or anti-tumor agents, as well as fragments of the proteins and the DNA, cDNA, antisense RNA and DNA segments corresponding to the proteins. This invention also comprises methods for isolating the proteins and therapeutic uses related to the proteins.

Method For Isolating Terpene Trilactones (Ginkgolides, Bilobalide) From Leaves And Pharmaceutical Powders Of Ginkgo Biloba

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US Patent:
6844451, Jan 18, 2005
Filed:
Jul 7, 2003
Appl. No.:
10/615346
Inventors:
Dirk Lichtblau - Halle, DE
Nina Berova - New York NY, US
John Berger - Oro Valley AZ, US
Koji Nakanishi - New York NY, US
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
C07D30777
C07D30793
US Classification:
549297, 549298
Abstract:
A method of isolating terpene trilactones from plant material or extract comprising the steps of suspending the plant material or extract in either water or an aqueous solution of an oxidation reagent; extracting the terpene trilactones using an acceptable extraction agent; separating the organic layer from the aqueous layer; washing the organic layer with an acceptable aqueous salt or hydroxide solution, which may be an alkaline solution; and drying the organic layer to form a dried extract containing terpene trilactones. Further purification by treatment with or filtration over activated charcoal, by treatment with or filtration over alumina and by recrystallization with an acceptable solvent or solvent mixture leads to extracts with a content of terpene trilactones higher than 50%. Unwanted levels of ginkgolic acids are reduced to acceptable levels by reversed phase chromatography.

Analogs Of Terpene Trilactones From And Related Compounds And Uses Thereof

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US Patent:
7145021, Dec 5, 2006
Filed:
Mar 28, 2003
Appl. No.:
10/401931
Inventors:
Makiko Suehiro - White Plains NY, US
Koji Nakanishi - New York NY, US
Stine B. Vogensen - Copenhagen, DK
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
C07D 307/77
US Classification:
549297, 546164, 5462841, 544335
Abstract:
The subject invention provides compounds having the structure:.

Synthesis Of Derivatives Of Ginkgolide C

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US Patent:
7429670, Sep 30, 2008
Filed:
Aug 24, 2004
Appl. No.:
10/925209
Inventors:
Koji Nakanishi - New York NY, US
Stanislav Jaracz - Trinec, CZ
Kristian Stromgaard - Roskilde, DK
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
C07D 305/14
A01K 43/12
US Classification:
549265, 514443
Abstract:
The subject invention provides ginkgolide C derivatives compounds having the structure:.

Analogs Of Terpene Trilactones From And Related Compounds And Uses Thereof

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US Patent:
7473788, Jan 6, 2009
Filed:
Dec 5, 2006
Appl. No.:
11/634429
Inventors:
Makiko Suehiro - White Plains NY, US
Koji Nakanishi - New York NY, US
Stine B. Vogensen - Copenhagen N, DK
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
C07D 305/14
A01K 43/12
US Classification:
549265, 514443
Abstract:
The subject invention provides compounds having the structure:.

Isbn (Books And Publications)

Comprehensive Natural Products Chemistry: Polyketides and Other Secondary Metabolites Including Fatty Acids and Their Derivatives

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Author

Koji Nakanishi

ISBN #

0080431534

Comprehensive Natural Products Chemistry: Isoprenoids Including Carotenoids and Steroids

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Author

Koji Nakanishi

ISBN #

0080431542

Comprehensive Natural Products Chemistry: Carbohydrates and Their Derivatives Including Tannins Cellulose and Related Lignins

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Author

Koji Nakanishi

ISBN #

0080431550

Comprehensive Natural Products Chemistry: Amino-Acids Peptides Porphyrins and Alkaloids

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Author

Koji Nakanishi

ISBN #

0080431569

Comprehensive Natural Products Chemistry: Enzymes Enzyme Mechanisms Proteins and Aspects of No Chemistry

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Author

Koji Nakanishi

ISBN #

0080431577

Comprehensive Natural Products Chemistry: Prebiotic Chemistry Molecular Fossils Nucleosides and Rna

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Author

Koji Nakanishi

ISBN #

0080431585

Comprehensive Natural Products Chemistry: DNA and Aspects of Molecular Biology

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Author

Koji Nakanishi

ISBN #

0080431593

Comprehensive Natural Products Chemistry: Miscellaneous Natural Products Including Marine Natural Products Pheromones Plant Hormones and Aspects of Ecology

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Author

Koji Nakanishi

ISBN #

0080431607

Koji N Nakanishi from Cliffside Park, NJ, age ~99 Get Report