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Kevin Loutherback Phones & Addresses

  • Rochester, MN
  • 2466 Hilgard Ave APT 306, Berkeley, CA 94709
  • Norco, CA
  • Princeton, NJ
  • Ft Mitchell, KY

Resumes

Resumes

Kevin Loutherback Photo 1

Assistant Professor

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Location:
Berkeley, CA
Industry:
Biotechnology
Work:
Mayo Clinic
Assistant Professor

Berkeley Lights, Inc. Nov 2015 - Feb 2017
Senior Consumables Design Engineer

Lawrence Berkeley National Laboratory Oct 2011 - Oct 2015
Postdoctoral Fellow

Princeton University 2007 - 2011
Graduate Student Researcher
Education:
Princeton University 2006 - 2011
Doctorates, Doctor of Philosophy, Electrical Engineering, Philosophy
Uc Irvine 2002 - 2006
Bachelors, Electrical Engineering, Physics
Skills:
Microfluidics
Microfabrication
Comsol
Matlab
Particle Separation
Multilayer Soft Lithography
Pdms
Ftir
Solidworks
Fluorescence Microscopy
Grant Writing
Electronics
Data Analysis
Instrumentation
Latex
Cell Sorting
Languages:
English
Kevin Loutherback Photo 2

Kevin Loutherback

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Publications

Us Patents

Bump Array Device Having Asymmetric Gaps For Segregation Of Particles

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US Patent:
20100059414, Mar 11, 2010
Filed:
Jul 24, 2009
Appl. No.:
12/509175
Inventors:
James C. Sturm - Princeton NJ, US
Robert Austin - Princeton NJ, US
Kevin Loutherback - Princeton NJ, US
Keith Morton - St-Bruno-de-Montarville, CA
Jason Puchalla - Princeton NJ, US
Assignee:
The Trustees of Princeton University - Princeton NJ
International Classification:
B03B 5/00
US Classification:
209155
Abstract:
The disclosure relates to obstacle array devices (also known as bump array devices) for separating populations of particles by size. Improvements over previous obstacle array devices are realized by causing the fluid velocity profile across gaps between obstacles to be asymmetrical with respect to the plane that bisects the gap and is parallel to the direction of bulk fluid flow. Such asymmetry can be achieved by selecting the shape(s) of the obstacles bounding the gap such that the portions of the obstacles upstream from, downstream from, or bridging the narrowest portion of the gap are asymmetrical with respect to that plane. Improvements are also realized by using obstacles that have sharp edges bounding the gaps. Other improvements are realized by selecting obstacle shapes such that the critical particle dimensions defined by the gaps in two different fluid flow directions differ.

Bump Array Device Having Asymmetric Gaps For Segregation Of Particles

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US Patent:
20130098813, Apr 25, 2013
Filed:
Dec 7, 2012
Appl. No.:
13/708425
Inventors:
Kevin Loutherback - Berkeley CA, US
James C. Sturm - Princeton NJ, US
Robert Austin - Princeton NJ, US
Keith Morton - Boucherville, CA
Jason Puchalla - Princeton NJ, US
Assignee:
THE TRUSTEES OF PRINCETON UNIVERSITY - Princeton NJ
International Classification:
B03B 5/00
US Classification:
209675
Abstract:
The disclosure relates to obstacle array devices (also known as bump array devices) for separating populations of particles by size. Improvements over previous obstacle array devices are realized by causing the fluid velocity profile across gaps between obstacles to be asymmetrical with respect to the plane that bisects the gap and is parallel to the direction of bulk fluid flow. Such asymmetry can be achieved by selecting the shape(s) of the obstacles bounding the gap such that the portions of the obstacles upstream from, downstream from or bridging the narrowest portion of the gap are asymmetrical with respect to that plane.Improvements are also realized by using obstacles that have sharp edges bounding the gaps. Other improvements are realized by selecting obstacle shapes such that the critical particle dimensions defined by the gaps in two different fluid flow directions differ.

Methods, Systems And Kits For In-Pen Assays

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US Patent:
20220250071, Aug 11, 2022
Filed:
Nov 23, 2021
Appl. No.:
17/534350
Inventors:
- Emeryville CA, US
Matthew E. FOWLER - Emeryville CA, US
Phillip J. M. ELMS - Emeryville CA, US
Kevin D. LOUTHERBACK - Emeryville CA, US
Jian GONG - Emeryville CA, US
J. Tanner NEVILL - Emeryville CA, US
Gang F. WANG - Emeryville CA, US
Gregory G. LAVIEU - Emeryville CA, US
John A. TENNEY - Emeryville CA, US
Aathavan KARUNAKARAN - Emeryville CA, US
Anupam SINGHAL - Emeryville CA, US
International Classification:
B01L 3/00
G01N 21/64
B03C 5/02
B03C 5/00
B01L 9/00
G06T 7/00
Abstract:
Methods, systems and kits are described herein for detecting the results of an assay. In particular, the methods, systems and devices of the present disclosure rely on a difference between the diffusion rates of a reporter molecule and an analyte of interest in order to quantify an amount of analyte in a microfluidic device. The analyte may be a secreted product of a biological micro-object.

Antigen-Presenting Synthetic Surfaces, Covalently Functionalized Surfaces, Activated T Cells, And Uses Thereof

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US Patent:
20200299351, Sep 24, 2020
Filed:
Jan 15, 2020
Appl. No.:
16/743849
Inventors:
- Emeryville CA, US
Alexander J. Mastroianni - Alameda CA, US
Shao Ning Pei - Albany CA, US
Annamaria Mocciaro - San Francisco CA, US
Kevin D. Loutherback - Rochester MN, US
Yelena Bronevetsky - Alameda CA, US
Guido K. Stadler - San Francisco CA, US
Andrew W. McFarland - Berkeley CA, US
Kevin T. Chapman - Emeryville CA, US
Duane Smith - Berkeley CA, US
Natalie C. Marks - Albany CA, US
Amanda L. Goodsell - Alameda CA, US
Assignee:
Berkeley Lights, Inc. - Emeryville CA
International Classification:
C07K 14/725
C07K 16/28
G01N 33/50
C07K 14/74
Abstract:
In biosciences and related fields, it can be useful to modify surfaces of apparatuses, devices, and materials that contact biomaterials such as biomolecules and biological micro-objects. Described herein are surface modifying and surface functionalizing reagents, preparation thereof, and methods for modifying surfaces to activate T Lymphocytes.

Proto-Antigen-Presenting Synthetic Surfaces, Activated T Cells, And Uses Thereof

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US Patent:
20200139362, May 7, 2020
Filed:
Oct 17, 2019
Appl. No.:
16/656520
Inventors:
- Emeryville CA, US
Alexander J. MASTROIANNI - Alameda CA, US
Shao Ning PEI - Albany CA, US
Annamaria MOCCIARO - San Francisco CA, US
Kevin D. LOUTHERBACK - Berkeley CA, US
Yelena BRONEVETSKY - Alameda CA, US
Guido K. STADLER - San Francisco CA, US
Andrew W. MCFARLAND - Berkeley CA, US
Kevin T. CHAPMAN - Emeryville CA, US
Duane SMITH - Berkeley CA, US
Natalie C. MARKS - Albany CA, US
Amanda L. GOODSELL - Alameda CA, US
Assignee:
Berkeley Lights, Inc. - Emeryville CA
International Classification:
B01L 3/00
C07K 14/74
G01N 33/68
G01N 33/50
Abstract:
Proto-antigen-presenting surfaces and related kits, methods, and uses are provided. The proto-antigen-presenting surface can comprise a plurality of primary activating molecular ligands comprising a major histocompatibility complex (MHC) molecule configured to bind to a T cell receptor (TCR) of a T cell and a plurality of of co-activating molecular ligands each including a TCR co-activating molecule or an adjunct TCR activating molecule, wherein an exchange factor is bound to the MHC molecules. Exchange factors include, e.g., dipeptides such as GL, GF, GR, etc. Proto-antigen-presenting surfaces can be used to rapidly prepare antigen-presenting surfaces comprising one or more peptide antigens of interest by contacting the proto-antigen-presenting surface with one or more peptide antigens so as to displace the exchange factor. As such, the disclosure facilitates rapid evaluation of the immunogenicity of peptide antigens for activating T lymphocytes.

Methods, Systems And Kits For In-Pen Assays

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US Patent:
20190240665, Aug 8, 2019
Filed:
Oct 15, 2018
Appl. No.:
16/160816
Inventors:
- Emeryville CA, US
Matthew E. FOWLER - Emeryville CA, US
Phillip J. M. ELMS - Emeryville CA, US
Kevin D. LOUTHERBACK - Emeryville CA, US
Jian GONG - Emeryville CA, US
Tanner J. NEVILL - Emeryville CA, US
Gang F. WANG - Emeryville CA, US
Gregory G. LAVIEU - Emeryville CA, US
John A. TENNEY - Emeryville CA, US
Aathavan KARUNAKARAN - Emeryville CA, US
International Classification:
B01L 3/00
G06T 7/00
B01L 9/00
Abstract:
Methods, systems and kits are described herein for detecting the results of an assay. In particular, the methods, systems and devices of the present disclosure rely on a difference between the diffusion rates of a reporter molecule and an analyte of interest in order to quantify an amount of analyte in a microfluidic device. The analyte may be a secreted product of a biological micro-object.

Spectroscopy Imaging And Analysis Of Live Cells

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US Patent:
20180299374, Oct 18, 2018
Filed:
Oct 11, 2016
Appl. No.:
15/766594
Inventors:
- Oakland CA, US
Kevin Loutherback - Berkeley CA, US
Liang Chen - Walnut Creek CA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
G01N 21/3563
G01N 27/02
B01L 3/00
Abstract:
Disclosed herein are systems, methods, systems and devices for measurement and visualization of chemical dynamics in living cells or tissues for diagnostic pathology. Devices can be open- or closed-channel microfluidic membrane devices for long-term IR spectroscopy of live adherent cells and ultimately for rapidly identifying time-dependent spectral features indicative of chemical abnormality in individual cells.
Kevin D Loutherback from Rochester, MN, age ~40 Get Report