Resumes
Resumes
Kemal Sahin Phones & Addresses
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5700 5Th St, Pittsburgh, PA 15232 (412) 365-0252
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3245 Bishop St, Cincinnati, OH 45220
Publications
Us Patents
System And Method For Determining Optimal Reaction Parameters Using Continuously Running Process
View pageUS Patent:
20050013738, Jan 20, 2005
Filed:
Apr 14, 2004
Appl. No.:
10/824186
Inventors:
Thomas Schwalbe - Brookline MA, US
Volker Autze - Frankfurt am Main, DE
Sebastian Oberbeck - Weilburg, DE
Ansgar Kursawe - Frankfurt, DE
Kemal Sahin - Pittsburgh PA, US
Volker Autze - Frankfurt am Main, DE
Sebastian Oberbeck - Weilburg, DE
Ansgar Kursawe - Frankfurt, DE
Kemal Sahin - Pittsburgh PA, US
Assignee:
Cellular Process Chemistry, Inc. - Cambridge MA
International Classification:
G01N035/00
US Classification:
422067000, 436043000
Abstract:
A reaction system enables a plurality of optimization experiments for a reaction to be performed continuously, to enable optimal reaction parameters to be determined. Dilution pumps are included to automatically vary the solvent mixed with reactants so a concentration of each reactant can be selectively varied. The reactants are introduced into a reaction module selectively coupled to residence time chambers or directly to an analytical unit. The analytical unit determines the yield and/or quality for each optimization experiment, enabling optimal parameters to be determined. Residence time chambers can be employed sequentially to enable total residence time to be varied. The controller performs as many experiments as required to enable each parameter to be varied according to a predefined testing program and can redefine a testing program based on the results from previous experiments. At least two reaction parameters can be varied according to periodic functions to further enhance analytical efficiency.
System And Method For Determining Optimal Reaction Parameters Using Continuously Running Process
View pageUS Patent:
20060234381, Oct 19, 2006
Filed:
Jun 22, 2006
Appl. No.:
11/425895
Inventors:
Thomas Schwalbe - Brookline MA, US
Volker Autze - Frankfurt am Main, DE
Sebastian Oberbeck - Weilburg, DE
Ansgar Kursawe - Frankfurt, DE
Kemal Sahin - Pittsburgh PA, US
Volker Autze - Frankfurt am Main, DE
Sebastian Oberbeck - Weilburg, DE
Ansgar Kursawe - Frankfurt, DE
Kemal Sahin - Pittsburgh PA, US
Assignee:
Cellular Process Chemistry, Inc. - Cambridge MA
International Classification:
G01N 31/10
US Classification:
436034000, 436043000
Abstract:
A reaction system enables a plurality of optimization experiments for a reaction to be performed continuously, to enable optimal reaction parameters to be determined. Dilution pumps are included to automatically vary the solvent mixed with reactants so a concentration of each reactant can be selectively varied. The reactants are introduced into a reaction module selectively coupled to residence time chambers or directly to an analytical unit. The analytical unit determines the yield and/or quality for each optimization experiment, enabling optimal parameters to be determined. Residence time chambers can be employed sequentially to enable total residence time to be varied. The controller performs as many experiments as required to enable each parameter to be varied according to a predefined testing program and can redefine a testing program based on the results from previous experiments. At least two reaction parameters can be varied according to periodic functions to further enhance analytical efficiency.