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Kazimir Sestanj Phones & Addresses

  • Tucson, AZ
  • 2 Harper Rd, Monmouth Junction, NJ 08852 (908) 329-6167
  • 4852 E Paseo Del Bac, Tucson, AZ 85718

Publications

Us Patents

N-[[6-Methoxy-5-(Trifluoromethyl)-1-Naphthalenyl]-Thioxomethyl]-N-Methylg Lycine S-Oxide And The Amide Thereof

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US Patent:
48534846, Aug 1, 1989
Filed:
Oct 28, 1987
Appl. No.:
7/113691
Inventors:
Eckhardt S. Ferdinandi - Princeton NJ
Michael S. Malamas - Plainsboro NJ
Kazimir Sestanj - Monmouth Junction NJ
Surendra N. Sehgal - Princeton NJ
Assignee:
American Home Products Corporation - New York NY
International Classification:
C07C15305
US Classification:
564 74
Abstract:
Disclosed herein are N-[[6-methoxy-5-(trifluoromethyl)-1-naphthalenyl]thioxomethyl]-N-methylgly cine S-oxide (tolrestat S-oxide) and the amide thereof and methods of their preparation. The S-oxides are new aldose reductase inhibitors useful for the treatment or prevention of diabetic complications.

N-Acyl-N-Naphthoylglycines As Aldose Reductase Inhibitors

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US Patent:
48207276, Apr 11, 1989
Filed:
Dec 23, 1987
Appl. No.:
7/137406
Inventors:
Jay E. Wrobel - Lawrenceville NJ
Kazimir Sestanj - Monmouth Junction NJ
Assignee:
American Home Products Corporation - New York NY
International Classification:
C07C125065
A61K 3127
US Classification:
514510
Abstract:
Disclosed herein are N-acyl-N-naphthoylglycines and methods of their preparation. The N-acyl-N-naphthoylglycines are novel aldose reductase inhibitors useful for the treatment or prevention of diabetic complications.

N-Acyl-N-Naphthoylglycines As Aldose Reductase Inhibitors

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US Patent:
49259687, May 15, 1990
Filed:
Jan 9, 1989
Appl. No.:
7/294712
Inventors:
Kazimir Sestanj - Monmouth Junction NJ
Jay E. Wrobel - Lawrenceville NJ
Joseph M. Kelly - Bloomfield NJ
Assignee:
American Home Products Corporation - New York NY
International Classification:
C07C175065
US Classification:
560 21
Abstract:
Disclosed herein are N-acyl-N-naphthoylglycines and methods of their preparation. The N-acyl-N-naphthoylglycines are novel aldose reductase inhibitors useful for the treatment or prevention of diabetic complications.

N-[[5-(Trifluoromethyl)-6-Methoxy-1-Naphthalenyl]-Thioxomethyl And Carbonyl]-N-Methylglycinamides

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US Patent:
46720596, Jun 9, 1987
Filed:
Nov 18, 1985
Appl. No.:
6/799036
Inventors:
Kazimir Sestanj - Monmouth Junction NJ
Eckhardt S. Ferdinandi - Princeton NJ
Assignee:
American Home Products Corporation - New York NY
International Classification:
A61K 3170
US Classification:
514 62
Abstract:
Disclosed herein are tolrestat and oxotolrestat amides and methods of preparation. The amides are new aldose reductase inhibitors useful for the treatment or prevention of diabetic complications.

N-(6-Methoxy-5-(Trifluoromethyl)-1-Naphthalenyl)-Substituted Imino)Methyl)-N-Methylglycines

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US Patent:
49067664, Mar 6, 1990
Filed:
Mar 20, 1989
Appl. No.:
7/325609
Inventors:
Jay E. Wrobel - Lawrenceville NJ
Kazimir Sestanj - Monmouth Junction NJ
Assignee:
American Home Products Corporation - New York NY
International Classification:
C07C14380
US Classification:
558 390
Abstract:
Disclosed herein are N-[[6-methoxy-5-(trifluoromethyl)-1-naphthalenyl][substituted imino]methyl]-N-methylglycines and methods for their preparation. The N-methylglycines are new aldose reductase inhibitors useful for the treatment or prevention of diabetic complications.

N-Naphthoylglycines As Aldose Reductase Inhibitors

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US Patent:
49622242, Oct 9, 1990
Filed:
Aug 22, 1989
Appl. No.:
7/397623
Inventors:
Jay E. Wrobel - Lawrenceville NJ
Kazimir Sestanj - Monmouth Junction NJ
Assignee:
American Home Products Corporation - New York NY
International Classification:
C07C26100
US Classification:
560 28
Abstract:
Disclosed herein are N-naphthoylglycines and methods of their preparation. The N-naphthoylglycines are novel aldose reductase inhibitors useful for the treatment or prevention of diabetic complications.

Naphthalenylsulfonylimidazolidinediones And Their Thioxo Analogs Useful As Aldose Reductase Inhibitors

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US Patent:
47436115, May 10, 1988
Filed:
Feb 9, 1987
Appl. No.:
7/012592
Inventors:
Michael S. Malamas - Plainsboro NJ
Kazimir Sestanj - Monmouth Junction NJ
Assignee:
American Home Products Corp. - New York NY
International Classification:
A61K 31415
C07D40330
US Classification:
514390
Abstract:
Disclosed herein are naphthalenylsulfonylimidazolidinediones and their thioxo analogs and methods for their preparation. The compounds are new aldose reductase inhibitors useful for the treatment or prevention of diabetic complications.

N-[6-Methoxy-5-(Perfluoroalkyl)-1-Naphtholyl]-N-Methylglycines And Their Thionaphthoyl Analogs

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US Patent:
46044060, Aug 5, 1986
Filed:
Nov 16, 1984
Appl. No.:
6/672015
Inventors:
Francesco Bellini - Mt. Royal, CA
Kazimir Sestanj - Rocky Hill NJ
Assignee:
Ayerst, McKenna & Harrison, Inc. - Montreal
International Classification:
A61K 3119
A61K 31195
C07C10384
C07C153063
US Classification:
514562
Abstract:
Disclosed herein are new aldose reductase inhibitors of the formula ##STR1## wherein n is an integer from 1 to 5 and X is a chalcogen, and methods of preparation. The derivatives are useful for treating or preventing diabetic complications.
Kazimir Sestanj from Tucson, AZDeceased Get Report