US Patent:
20110305661, Dec 15, 2011
Inventors:
John Tucker - San Diego CA, US
Sergey Sviridov - Moscow, RU
Leonid Brodsky - Rehovet, IL
Catherine Burkhart - Collins NY, US
Andrei Purmal - Orchard Park NY, US
Katerina Gurova - Orchard Park NY, US
Andrei Gudkov - East Aurora NY, US
International Classification:
A61K 31/403
C07D 209/94
C07D 209/88
C07D 403/10
C07D 413/06
C07D 401/06
A61K 31/506
A61K 31/5377
A61K 31/454
A61K 31/439
A61K 31/55
A61P 35/00
A61P 35/02
A61K 38/19
A61P 29/00
A61P 19/02
A61P 17/06
A61P 33/02
A61P 33/06
A61P 9/10
A61P 17/00
A61P 17/02
A61P 19/10
C07D 209/86
US Classification:
424 851, 548441, 548418, 548420, 544333, 544142, 546200, 546112, 540602, 514411, 514410, 514256, 5142328, 514323, 514299, 51421708
Abstract:
Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases.