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Karin Tietje Phones & Addresses

  • Mundelein, IL
  • Lane, IL

Publications

Us Patents

Diazabicyclic Central Nervous System Active Agents

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US Patent:
6809105, Oct 26, 2004
Filed:
Apr 12, 2001
Appl. No.:
09/833914
Inventors:
Michael R. Schrimpf - Grayslake IL
Karin R. Tietje - Mundelein IL
Richard B. Toupence - South Plainfield IL
Jianguo Ji - Libertyville IL
Anwer Basha - Lake Forest IL
William H. Bunnelle - Mundelein IL
Jerome F. Daanen - Racine WI
Jennifer M. Pace - Grayslake IL
Kevin B. Sippy - Antioch IL
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 3144
US Classification:
514300, 514314, 514338, 546113, 546175, 5462767
Abstract:
Compounds of formula I pharmaceutical compositions of these compounds, and use of said compositions to control synaptic transmission in mammals.

Diazabicyclic Central Nervous System Active Agents

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US Patent:
7319106, Jan 15, 2008
Filed:
Mar 26, 2004
Appl. No.:
10/810999
Inventors:
Michael R. Schrimpf - Grayslake IL, US
Karin R. Tietje - Mundelein IL, US
Richard B. Toupence - South Plainfield NJ, US
Jianguo Ji - Libertyville IL, US
Anwer Basha - Lake Forest IL, US
William H. Bunnelle - Mundelein IL, US
Jerome F. Daanen - Racine WI, US
Jennifer M. Pace - Grayslake IL, US
Kevin B. Sippy - Antioch IL, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61P 25/00
A61K 31/44
C07D 401/00
US Classification:
514300, 514338, 546113, 5462767
Abstract:
Compounds of formula I.

Substituted Diazabicycloalkane Derivatives

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US Patent:
7399765, Jul 15, 2008
Filed:
Sep 16, 2004
Appl. No.:
10/942035
Inventors:
William H. Bunnelle - Mundelein IL, US
Jianguo Ji - Libertyville IL, US
Tao Li - Grayslake IL, US
Jennifer M. Pace - Grayslake IL, US
Karin R. Tietje - Mundelein IL, US
Kathleen H. Mortell - Chicago IL, US
Diana L. Nersesian - Gurnee IL, US
Michael R. Schrimpf - Grayslake IL, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 31/501
A61K 31/5025
A61K 31/4427
A61K 31/42
A61K 31/4436
C07D 401/04
C07D 403/04
C07D 405/04
C07D 409/04
C07D 471/04
C07D 491/04
C07D 498/04
C07D 513/04
C07D 515/04
A61P 29/00
C07D 231/12
C07D 417/04
C07D 285/08
C07D 285/12
C07D 239/42
C07D 263/34
C07D 413/02
C07D 413/14
C07D 271/107
C07D 487/04
C07D 215/12
C07D 261/12
C07D 401/14
C07D 413/04
C07D 23/56
A61K 31/41
A61K 31/425
A61K 31/426
A61K 31/427
A61K 31/4245
A61K 31/441
A61K 31/422
A61K 31/4155
US Classification:
51425206, 544238, 544333, 546113, 546256, 5462764, 546176, 5462767, 5462774, 51425202, 51425205, 51425204, 514256, 514406, 514372, 514363, 514361, 514374, 514364, 514339, 514357, 514378, 514338, 5483751, 548181, 548128, 548136, 548235, 548143, 548247, 5483625
Abstract:
Compounds of formula (I)Z-Ar—Ar  (I)wherein Z is a diazabicyclic amine, Aris a 5- or 6-membered aromatic ring, and Aris selected from the group consisting of an unsubstituted or substituted 5- or 6-membered heteroaryl ring; unsubstituted or substituted bicyclic heteroaryl ring; 3,4-(methylenedioxy)phenyl; carbazolyl; tetrahydrocarbazolyl; naphthyl; and phenyl; wherein the phenyl is substituted with 0, 1, 2, or 3 substituents in the meta- or para-positions. The compounds are useful in treating conditions or disorders prevented by or ameliorated by α7 nAChR ligands. Also disclosed are pharmaceutical compositions comprising compounds of formula (I) and methods for using such compounds and compositions.

Indoles Are Cannabinoid Receptor Ligands

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US Patent:
7560481, Jul 14, 2009
Filed:
Dec 21, 2005
Appl. No.:
11/315862
Inventors:
Jennifer M. Frost - Grayslake IL, US
Karin R. Tietje - Mundelein IL, US
Michael J. Dart - Highland Park IL, US
Michael D. Meyer - Lake Villa IL, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 31/55
A61K 31/5377
A61K 31/454
A61K 31/4439
A61K 31/404
C07D 403/06
C07D 413/06
C07D 401/06
C07D 209/12
US Classification:
514419, 51421708, 5142352, 514323, 514414, 540602, 544143, 544373, 546201, 5462781, 548465, 548193
Abstract:
The present invention provides novel compounds of Formula (I).

Diazabicyclic Central Nervous System Active Agents

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US Patent:
7598236, Oct 6, 2009
Filed:
Dec 15, 2007
Appl. No.:
11/957424
Inventors:
Michael R. Schrimpf - Grayslake IL, US
Karin R. Tietje - Mundelein IL, US
Richard B. Toupence - West Milford NJ, US
Jianguo Ji - Libertyville IL, US
Anwer Basha - Lake Forest IL, US
William H. Bunnelle - Mundelein IL, US
Jerome F. Daanen - Racine WI, US
Jennifer M. Frost - Grayslake IL, US
Kevin B. Sippy - Antioch IL, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61P 25/00
A61K 31/397
C07D 205/00
C07D 471/00
C07D 487/00
C07D 237/30
C07D 401/00
C07D 421/00
C07D 241/00
C07D 239/00
C07D 403/00
C07D 215/00
C07D 275/00
C07D 417/00
C07D 261/00
US Classification:
51421016, 514300, 514314, 514338, 544237, 544238, 544242, 544316, 544330, 544334, 544335, 544336, 544406, 544407, 544408, 544409, 546113, 546114, 546115, 546116, 546168, 546169, 546170, 546171, 546172, 546175, 546176, 5462681, 5462767, 548213, 548214, 548243, 548246, 548247, 548248, 548453, 548950, 548953
Abstract:
Compounds of formula I.

Indoles Are Cannabinoid Receptor Ligands

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US Patent:
7750039, Jul 6, 2010
Filed:
Feb 13, 2009
Appl. No.:
12/370727
Inventors:
Jennifer M. Frost - Grayslake IL, US
Karin Tietje - Mundelein IL, US
Michael J. Dart - Highland Park IL, US
Michael D. Meyer - Lake Villa IL, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61K 31/55
A61K 31/5377
A61K 31/454
A61K 31/4439
A61K 31/404
US Classification:
514419, 51421708, 5142352, 514323, 514414
Abstract:
The present invention provides novel compounds of Formula (I).

Substituted Diazabicycloalkane Derivatives Having Affinity For Nicotinic Acetylcholine Receptors

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US Patent:
7872010, Jan 18, 2011
Filed:
Jun 3, 2008
Appl. No.:
12/132009
Inventors:
Jennifer M. Frost - Grayslake IL, US
Jianguo Ji - Libertyville IL, US
Tao Li - Grayslake IL, US
Diana L. Nersesian - Gurnee IL, US
Karin R. Tietje - Mundelein IL, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
C07D 401/00
C07D 401/14
C07D 239/34
C07D 487/14
A61K 31/4462
A61K 31/506
A61K 31/501
A61K 31/4704
US Classification:
51425203, 514328, 514274, 514314, 544316, 544238, 5462767, 546256, 546167
Abstract:
Provided herein are compositions of a class of substituted diazabicycloalkane derivative compounds, which are useful as modulators of nicotinic acetylcholine receptors. The compounds are useful in treating conditions and disorders prevented by, or ameliorated by, nicotinic acetylcholine receptors.

Diazabicyclic Central Nervous System Active Agents

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US Patent:
8119635, Feb 21, 2012
Filed:
Aug 19, 2009
Appl. No.:
12/543822
Inventors:
Michael R. Schrimpf - Grayslake IL, US
Karin R. Tietje - Mundelein IL, US
Richard B. Toupence - West Milford NJ, US
Jianguo Ji - Shanghai, CN
Anwer Basha - Lake Forest IL, US
William H. Bunnelle - Mundelein IL, US
Jerome F. Daanen - Racine WI, US
Jennifer M. Frost - Grayslake IL, US
Kevin B. Sippy - Antioch IL, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
A61P 25/00
A61K 31/501
A61K 31/4965
A61K 31/505
A61K 31/44
C07D 237/30
C07D 239/02
C07D 241/02
C07D 471/00
US Classification:
514248, 51425204, 51425505, 514256, 514274, 514300, 514301, 514302, 544237, 544238, 544316, 544330, 544332, 544336, 544406, 544407, 544408, 544409, 546113, 546114, 546115, 546116, 546122
Abstract:
Compounds of formula I.
Karin R Tietje from Mundelein, IL, age ~89 Get Report