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Kae M Pusic

from Honolulu, HI
Age ~43

Kae Pusic Phones & Addresses

  • 1888 Kalakaua Ave APT 1301, Honolulu, HI 96815 (808) 341-0392
  • 7220 Heitz Ct, San Jose, CA 95120 (408) 568-4222
  • Davis, CA
  • 7220 Heitz Ct, San Jose, CA 95120

Work

Position: Professional/Technical

Resumes

Resumes

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Kae Pusic

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Industry:
Research
Work:
University of Hawaii at Manoa
Phd Candidate

University of Hawaii at Manoa
Ga Tropical Medicine and Medical Micr

Hawaiian Island Solar Inc.
Ga Tropical Medicine and Medical Micr

Cancer Research Center of Hawaii
Secretary
Education:
University of Hawaii at Manoa 2005 - 2010
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Kae Pusic

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Publications

Us Patents

Enhanced Malaria Msp-1 Subunit Vaccine

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US Patent:
20120231029, Sep 13, 2012
Filed:
Nov 18, 2010
Appl. No.:
13/510923
Inventors:
David E. Clements - Honolulu HI, US
Kae Myriam Pusic - Honolulu HI, US
George N.S. Hui - Honolulu HI, US
Assignee:
Hawaii Biotect Inc. - Aiei HI
University of Hawaii - Honolulu HI
International Classification:
A61K 39/002
A61P 37/04
A61P 33/06
C07K 14/445
C12P 21/02
US Classification:
4241911, 530300, 530350, 435 693
Abstract:
Recombinant subunit proteins derived from the MSP-1 C-terminal region of the parasite are described that have enhanced immunogenic properties. Selected regions of p33 have been combined with p19 to enhance the immunogenic potential of the p19 core region. As the constructs represent discontinuous segments fused to create unique proteins, the recombinant proteins expressed are not found in nature. The enhanced immunogenic potential of the disclosed recombinant proteins provided for strong, consistent and specific antibody responses. The disclosed recombinant subunit proteins are vaccine candidates for protection against infection with malaria.

Nanoparticle Based Immunological Stimulation

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US Patent:
20120189700, Jul 26, 2012
Filed:
Jan 16, 2012
Appl. No.:
13/350849
Inventors:
Zoraida Aguilar - Fayetteville AR, US
Yongqiang Wang - Springdale AR, US
Hengyi Xu - Springdale AR, US
George Hui - Honolulu HI, US
Kae Pusic - Honolulu HI, US
International Classification:
A61K 39/385
A61P 35/00
A61K 9/51
B82Y 5/00
US Classification:
424489, 4241931, 977773, 977774, 977810, 977811, 977906, 977917
Abstract:
A nanoparticle-based delivery system and methods for its use are disclosed. In one aspect, a nanoparticle-based delivery system comprising at least one molecule such as proteins, DNA/RNA or fragments thereof, carbohydrates, enzymes, chemicals, virus cells, bacteria, parts of a virus, parts of a bacteria, parts of a cell, part of a tissue, or a combination of one or more of these, which shall be referred to as immunogens, are chemically or physically combined with water soluble nanoparticles which, when administered to a living system, is capable of eliciting a desired immunological response. More particularly, the invention relates to nanoparticle-based delivery systems that are specifically engineered to enhance humoral or cellular immune response without the use of adjuvants.
Kae M Pusic from Honolulu, HI, age ~43 Get Report