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Jules John Magda

from Salt Lake City, UT
Age ~67

Jules Magda Phones & Addresses

  • 1412 Michigan Ave, Salt Lake City, UT 84105 (801) 633-7050 (801) 521-7529
  • 633 4Th Ave, Salt Lake City, UT 84103 (801) 521-7529
  • Slc, UT
  • Eden, UT
  • Watertown, WI

Work

Company: University of utah Position: Associate professor of chemical engineering

Education

Degree: PhD School / High School: University of Minnesota-Twin Cities 1979 to 1986 Specialities: chemical engineering

Skills

Rheology • Polymers • Biomaterials • Chemical Engineering • Biomedical Engineering • Petroleum • Aspen Plus • Nanotechnology • Characterization • Materials Science

Industries

Higher Education

Resumes

Resumes

Jules Magda Photo 1

Professor Of Chemical Engineering

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Location:
5654 east Elkhorn Dr, Eden, UT 84310
Industry:
Higher Education
Work:
University of Utah
associate professor of chemical engineering

AT&T Bell Laboratories 1986 - 1988
Postdoctoral Member of Technical Staff

University of Minnesota 1979 - 1986
Graduate Student in Chemical Engineering

Stanford University 1975 - 1979
undergraduate in chemical engineering
Education:
University of Minnesota-Twin Cities 1979 - 1986
PhD, chemical engineering
Stanford University 1975 - 1979
B.S., chemical engineering
Skills:
Rheology
Polymers
Biomaterials
Chemical Engineering
Biomedical Engineering
Petroleum
Aspen Plus
Nanotechnology
Characterization
Materials Science

Publications

Us Patents

Glucose Biosensor

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US Patent:
6475750, Nov 5, 2002
Filed:
Aug 23, 2000
Appl. No.:
09/644323
Inventors:
In Suk Han - Salt Lake City UT
You Han Bae - Salt Lake City UT
Dal Young Jung - Salt Lake City UT
Jules John Magda - Salt Lake City UT
Assignee:
M-Biotech, Inc. - Salt Lake City UT
International Classification:
C12Q 154
US Classification:
435 14, 435 26, 4352871, 436 95, 436148, 6048911, 6048921
Abstract:
A biosensor ( ) has a hydrogel ( ) in a rigid and referably biocompatible enclosure ( ). The hydrogel ( ) includes an immobilized glucose-binding molecule such as concanavalin A (Con A) and an immobilized hexose saccharide such as a-D-mannopyranoside. The immobilized hexose saccharide competitively binds with free glucose to the glucose-binding molecules, thus changing the number of crosslinks in the hydrogel ( ), which changes hydrogel swelling tendency and the pressure of the hydrogel in its confined space in proportion to the concentration of free glucose. By measuring the change in hydrogel pressure with a pressure transducer ( ), the biosensor ( ) is able to accurately measure the concentration of the tree glucose molecule without the problem of oxygen limitations and interference encountered by prior art biosensors. A battery ( ) powered telemeter ( ) operably engaged to the pressure transducer ( ) sends a radio data signal to a receiver ( ) containing an alarm system operably attached to a computer ( ). Furthermore, an alarm system utilizes such a sensor to automatically notify a person that the blood glucose level is outside a predetermined parameter, and/or to automatically inject an agent such as glucose or glycogen which will raise blood glucose levels.

Hydrogel Biosensor

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US Patent:
6514689, Feb 4, 2003
Filed:
Apr 20, 2001
Appl. No.:
09/839993
Inventors:
In Suk Han - Sandy UT
Jules John Magda - Salt Lake City UT
Seok Lew Lew - Salt Lake City UT
Young San Jean - Seoul, KR
Assignee:
M-Biotech, Inc. - Salt Lake City UT
International Classification:
C12Q 100
US Classification:
435 4, 4352871, 4352877, 6048911, 6048921
Abstract:
A biosensor ( ) has a hydrogel ( ) in a rigid and preferably biocompatible enclosure ( ). The hydrogel ( ) includes an immobilized analyte binding molecule (ABM) and an immobilized analyte. The immobilized analyte competitively binds with free analyte to the ABM, thus changing the number of crosslinks in the hydrogel ( ), which changes hydrogel swelling tendency (and thus the osmotic pressure) in its confined space in proportion to the concentration of free analyte concentration. By measuring the change in hydrogel pressure with a pressure transducer ( ), the biosensor ( ) is able to accurately measure the concentration of the free analyte molecule without the problem of oxygen limitations and interference encountered by prior art biosensors. A battery ( ) powered telemeter ( ) operably engaged to the pressure transducer ( ) sends a radio data signal to a receiver ( ) containing an alarm system operably attached to a computer ( ). Furthermore, an alarm system utilizes such a sensor to automatically notify a person that the analyte level is outside desired predetermined parameters, and/or to automatically inject an agent to counteract the adverse analyte levels.

Hydrophobically-Modified Hyaluronan And Methods Of Making And Using Thereof

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US Patent:
20130143821, Jun 6, 2013
Filed:
Feb 3, 2011
Appl. No.:
13/576994
Inventors:
Jules John Magda - Salt Lake City UT, US
Grant D. mith - Salt Lake City UT, US
Dmitry Bedrov - Salt Lake City UT, US
Jimmy W. Mays - Knoxville TN, US
Assignee:
UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION - Knoxville TN
UNIVERSITY OF UTAH RESEARCH FOUNDATION - Salt Lake City UT
International Classification:
A61K 38/14
US Classification:
514 167, 530322, 514 209, 514 188
Abstract:
Described herein are modified hyaluronans or the pharmaceutically-acceptable salt or ester thereof, wherein the modified hyaluronan comprises at least one hydrophobic polypeptide covalently bonded to hyaluronan. The modified hyaluronans can be used as viscosupplements in a number of medical applications. The modified hyaluronans can also be used in several biological and medical applications. Methods for preparing the modified hyaluronans are also provided herein.

Biosensor

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US Patent:
62681613, Jul 31, 2001
Filed:
May 11, 1999
Appl. No.:
9/308392
Inventors:
In Suk Han - Salt Lake City UT
You Han Bae - Salt Lake City UT
Jules J. Magda - Salt Lake City UT
Seong Gi Baek - Woodbury MN
Assignee:
M-Biotech, Inc. - Salt Lake City UT
International Classification:
C12Q 154
C12M 134
US Classification:
435 14
Abstract:
A biosensor (10) has a pH-sensitive polymeric hydrogel (30) in a rigid and preferably biocompatible enclosure (20). The hydrogel (30) includes an immobilized oxidoreductase enzyme such as glucose oxidase. The oxidoreductase enzyme catalyzes a chemical reaction consuming an organic molecule and producing a byproduct. The hydrogel (30) changes its osmotic pressure in proportion to the concentration of a byproduct. By measuring the change in osmotic pressure with a pressure transducer (40), the biosensor (10) is able to accurately measure the concentration of the organic molecule without the problem of interference encountered by prior art biosensors. A battery (64) powered telemeter (60) operably engaged to the pressure transducer (40) sends a radio data signal to a receiver (66) operably attached to a computer (62).

Smart Hydrogel Pillar And Film Resonators For Biomedical Sensing And Methods Of Fabrication

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US Patent:
20210338195, Nov 4, 2021
Filed:
Jul 2, 2021
Appl. No.:
17/366743
Inventors:
- Salt Lake City UT, US
Navid Farhoudi - Salt Lake City UT, US
Florian Solzbacher - Salt Lake City UT, US
Jules J. Magda - Salt Lake City UT, US
International Classification:
A61B 8/08
A61B 90/00
A61K 49/22
Abstract:
Microresonator structures including a top polymer film layer, a bottom polymer film layer, and a smart hydrogel structure sandwiched between the polymer film layers. An ultrasound resonator cavity having a resonance frequency is defined between the top and bottom polymer layers, and the smart hydrogel structure is configured to provide a change in height to the ultrasound resonator cavity due to volumetric expansion or contraction of the smart hydrogel structure, in response to interaction of the smart hydrogel structure with one or more predefined analytes in an in vivo or other environment. Related methods of use for determining the presence or concentration of a given target analyte, as well as methods of fabricating such microresonator structures are also described.

Implantable And Biodegradable Smart Hydrogel Micromechanical Resonators With Ultrasound Readout For Biomedical Sensing

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US Patent:
20210267573, Sep 2, 2021
Filed:
May 7, 2021
Appl. No.:
17/315039
Inventors:
- Salt Lake City UT, US
Florian Solzbacher - Salt Lake City UT, US
Navid Farhoudi - Salt Lake City UT, US
Steven M. Blair - Salt Lake City UT, US
Jules J. Magda - Salt Lake City UT, US
Lars B. Laurentius - Cottonwood Heights UT, US
Prattay Deepta Kairy - Salt Lake City UT, US
International Classification:
A61B 8/00
G10K 11/04
A61B 8/08
Abstract:
Systems and methods for measuring changes in smart hydrogel microresonator structures positioned in an in vivo or other environment, having an acoustic resonance frequency in an ultrasound range. The system includes a smart hydrogel microresonator structure positioned within the environment configured to exhibit a change in resonance frequency in response to interaction with one or more predefined analytes in the environment. The system includes an ultrasound transducer for querying the smart hydrogel microresonator structure at or near its resonance frequency. The system also includes a computer system configured to receive ultrasound data as provided by query of the smart hydrogel microresonator structure and to determine changes in resonance frequency, amplitude or intensity of the ultrasound query wave, or mean grayscale value (MGV) associated with the ultrasound data of the smart hydrogel microresonator structure due to the change in resonance frequency. Such change can be correlated to concentration of the analyte.

Low-Cost Microfluidic Sensors With Smart Hydrogel Patterned Arrays Using Electronic Resistive Channel Sensing For Readout

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US Patent:
20200114353, Apr 16, 2020
Filed:
Oct 14, 2019
Appl. No.:
16/601120
Inventors:
- Salt Lake City UT, US
Navid Farhoudi - Salt Lake City UT, US
Christopher F. Reiche - Salt Lake City UT, US
Julia Koerner - Salt Lake City UT, US
Swomitra Kumar Mohanty - Salt Lake City UT, US
Florian Solzbacher - Salt Lake City UT, US
Jules John Magda - Salt Lake City UT, US
International Classification:
B01L 3/00
G03F 7/20
G01N 27/12
Abstract:
Microfluidics sensor devices having an array of smart polymer hydrogel features for resistive channel analyte sensing via hydrogel swelling and de-swelling, and methods of manufacturing and using the same. Inexpensive, rapid-responsive, point-of-use sensors for monitoring disease biomarkers or environmental contaminants in, for example, drinking water, employ smart polymer hydrogels as recognition elements that can be tailored to detect almost any target analyte. Fabrication involves mask-templated UV photopolymerization to produce an array of smart hydrogel pillars, with large surface area-to-volume ratios, inside sub-millimeter channels located on microfluidics devices. The pillars swell or shrink upon contact aqueous solutions containing a target analyte, thereby changing the resistance of the microfluidic channel to ionic current flow when a bias voltage is applied to the system. Hence resistance measurements can be used to transduce hydrogel swelling changes into electrical signals. A portable potentiostat can be included to make the system suitable for point of use.

Systems, Methods, And Sensor Devices For Measuring Changes In Analyte-Sensitive Hydrogels

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US Patent:
20200093408, Mar 26, 2020
Filed:
Jun 12, 2018
Appl. No.:
16/621510
Inventors:
Stan Kanarowski - Salt Lake City UT, US
Jules John Magda - Salt Lake City UT, US
Mahender Nath Avula - Salt Lake City UT, US
Tatjana S. Bevans - Salt Lake City, US
Nassir F. Marrouche - Salt Lake City UT, US
Derek J. Sakata - Salt Lake City UT, US
Julia Koerner - Salt Lake City UT, US
Christopher Reiche - Salt Lake City UT, US
International Classification:
A61B 5/145
G01N 27/12
G01N 27/74
A61B 5/053
H01F 5/00
Abstract:
Systems, methods, and sensor devices for identifying one or more changes in a stimulus-responsive hydrogel include a sensor device having (i) a sensing structure and (ii) a stimulus-responsive hydrogel associated with a first side of the sensing structure. The sensing structure includes a flexible thin film polymer and an electric sensing element capable of electric impedance change, and the hydrogel is configured to dimensionally change in response to predefined stimuli such that a dimensional change of the hydrogel causes a change in an impedance property of the electric sensing element. Systems including such a sensor device can additionally include a meter in electrical communication with the sensor device to identify changes in the impedance properties of the structure and/or a catheter sheath configured for placement within an in vivo environment and is sized and shaped to receive the sensor device within a lumen thereof.
Jules John Magda from Salt Lake City, UT, age ~67 Get Report