US Patent:
20060281763, Dec 14, 2006
Inventors:
Jonathan Axon - Milpitas CA, US
Sarvajit Chakravarty - Mountain View CA, US
Barry Hart - Palo Alto CA, US
Glenn McEnroe - San Mateo CA, US
Alison Murphy - Milpitas CA, US
Karen Pontius - Aromas CA, US
Peijue Sheng - San Jose CA, US
Xiaojing Wang - Foster City CA, US
Shanthi Yellapregada - Milpitas CA, US
International Classification:
C07D 403/14
C07D 403/02
A61K 31/506
Abstract:
Certain appropriately substituted forms of pyrimidine having a pyridylamine group at C-4 of the pyrimidine and an amide group on the pyridine ring are useful in the treatment of conditions associated with excessive TGFβ activity.