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Joan Kobori Phones & Addresses

  • 974 Kewen Dr, San Marino, CA 91108 (626) 429-8626
  • 140 S Mentor Ave, Pasadena, CA 91106
  • 3600 Fairmeade Rd, Pasadena, CA 91107
  • 2123 Eveleth Ave, San Leandro, CA 94577
  • Newark, CA
  • 974 Kewen Dr, San Marino, CA 91108

Work

Company: Agouron institute 1997 Position: Program director

Education

Degree: Bachelors, Bachelor of Arts School / High School: University of California, Berkeley Specialities: Biochemistry

Emails

Industries

Non-Profit Organization Management

Resumes

Resumes

Joan Kobori Photo 1

Program Director

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Location:
Pasadena, CA
Industry:
Non-Profit Organization Management
Work:
Agouron Institute
Program Director

Baxter International Inc. 1993 - 1995
Senior Scientist

Caltech 1985 - 1992
Senior Research Fellow
Education:
University of California, Berkeley
Bachelors, Bachelor of Arts, Biochemistry
Stanford University
Doctorates, Doctor of Philosophy, Biochemistry

Business Records

Name / Title
Company / Classification
Phones & Addresses
Joan Kobori
Director, Program Director
THE AGOURON INSTITUTE
School/Educational Services
1055 E Colorado Blvd SUITE 250, Pasadena, CA 91106
1055 E Colo Blvd, Pasadena, CA 91106
(626) 577-0500

Publications

Us Patents

Positive And Positive/Negative Cell Selection Mediated By Peptide Release

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US Patent:
59687533, Oct 19, 1999
Filed:
Jun 7, 1995
Appl. No.:
8/482228
Inventors:
Janet Tseng-Law - Whitter CA
Joan A. Kobori - Pasadena CA
Roy Guillermo - Carson CA
Sam L. Helgerson - Pasadena CA
Robert J. Deans - Claremont CA
Assignee:
Nexell Therapeutics, Inc. - Irvine CA
International Classification:
G01N 33567
G01N 3353
C07K 400
C07K 500
US Classification:
435 721
Abstract:
The invention provides a non-enzymatic method for the release of cells which have been positively selected from a heterogeneous cell suspension by antibody-mediated binding to beads or other solid support. The method entails forming within the cell suspension a complex comprising the solid support linked to a primary antibody, which in turn is specifically bound to a cell surface antigen on the target cells. The complex is separated from the cell suspension, and then contacted with a specific peptide which binds to the primary antibody, displacing the antibody from the cell surface antigen, thereby releasing the target cell from the complex. The invention also provides methods for positive/negative cell selection wherein target cells having a first antigen are selected from a heterogeneous cell suspension containing undesired cells having a second antigen. The invention also provides methods for identifying a specific peptide useful for the release of a target cell from the binding of a specific primary antibody. The methods of the invention are particularly useful for the positive selection of CD34+ hematopoietic stem cells and the concomitant purging of undesired tumor cells or lymphocytes from the positively selected cell population.

Positive And Positive/Negative Cell Selection Mediated By Peptide Release

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US Patent:
60177195, Jan 25, 2000
Filed:
Jun 7, 1995
Appl. No.:
8/482528
Inventors:
Janet Tseng-Law - Whitter CA
Joan A. Kobori - Pasadena CA
Roy Guillermo - Carson CA
Sam L. Helgerson - Pasadena CA
Robert J. Deans - Claremont CA
Assignee:
Nexell Therapeutics, Inc. - Irvine CA
International Classification:
G01N 3353
G01N 33553
US Classification:
435 721
Abstract:
The invention provides a nonenzymic method for the release of cells which have been selected from a heterogeneous cell suspension by antibody-mediated binding to beads or other solid support. The method entails forming within the cell suspension a complex comprising the solid support linked to a primary monoclonal antibody, which in turn is bound to a cell surface antigen on the target cells. The complex is separated from the cell suspension, and then contacted with a specific peptide which binds to the primary antibody, displacing the antibody from the cell surface antigen, thereby releasing the target cell from the complex. The invention also provides methods for positive/negative cell selection wherein target cells having a first antigen are selected from a heterogeneous cell suspension containing undesired cells having a second antigen.
Joan Agnes Kobori from San Marino, CA, age ~71 Get Report