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Jiong Lan Phones & Addresses

  • Moraga, CA
  • 6401 Shellmound St, Emeryville, CA 94608
  • 3126 Oak Rd, Walnut Creek, CA 94597
  • Branford, CT
  • 10971 Caminito Alvarez, San Diego, CA 92126
  • Rochester, NY

Publications

Us Patents

Substituted Pyrazolo [3,4-D]Pyrimidines As Cytokine Modulators

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US Patent:
7569571, Aug 4, 2009
Filed:
Dec 23, 2004
Appl. No.:
10/584076
Inventors:
Qing Dong - San Diego CA, US
Jianqiang Wang - Acton MA, US
Hengyuan Lang - San Diego CA, US
Jiong Lan - Emeryville CA, US
Assignee:
Novartis AG - Basel
International Classification:
C07D 487/04
A61K 31/519
A61P 35/04
A61P 25/02
A61P 25/06
A61P 19/02
US Classification:
5142621, 544262
Abstract:
Provided are bicyclic heterocycle-based p38 kinase, including p38α and p38β kinase, inhibitors. Pharmaceutical compositions containing the compounds are also provided. Methods of use of the compounds and compositions are also provided, including methods of treatment, prevention, or amelioration of one or more symptoms of p38 kinase mediated diseases and disorders, including, but not limited to, inflammatory diseases and disorders.

P-38 Kinase Inhibitors

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US Patent:
7700622, Apr 20, 2010
Filed:
Jul 23, 2004
Appl. No.:
10/898581
Inventors:
Hengyuan Lang - San Diego CA, US
Jiong Lan - San Diego CA, US
Yunfeng Fang - San Diego CA, US
Assignee:
Novartis AG - Basel
International Classification:
A61K 31/44
C07D 211/00
A61K 31/517
C07D 239/88
US Classification:
514315, 514353, 546242, 546244, 546245
Abstract:
Compounds and compositions for modulating the activity of p38 kinases are provided, including p38α and p38β kinase. Methods for treating, preventing or ameliorating one or more symptoms of a p38 kinase mediated disease or disorder are also provided.

Thiazole Amides, Imidazole Amides And Related Analogues

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US Patent:
7728009, Jun 1, 2010
Filed:
Feb 16, 2006
Appl. No.:
11/816294
Inventors:
Wallace C. Pringle - Guilford CT, US
John M. Peterson - Durham CT, US
Linghong Xie - Guilford CT, US
Ping Ge - Durham CT, US
Yang Gao - Madison CT, US
Joseph W. Ochterski - Middlefield CT, US
Jiong Lan - Moraga CA, US
Assignee:
Neurogen Corporation - Branford CT
International Classification:
A61K 31/445
C07D 241/36
US Classification:
514317, 544366, 5462684, 548146, 548215, 5483351, 51425213, 514365, 514374, 514396
Abstract:
Thiazole amides, imidazole amides and related analogues of the Formula:.

Benzamide Derivatives As P-38 Kinase Inhibitors

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US Patent:
7754726, Jul 13, 2010
Filed:
Jul 23, 2004
Appl. No.:
10/565452
Inventors:
Hengyuan Lang - San Diego CA, US
Jiong Lan - San Diego CA, US
Yunfeng Fang - San Diego CA, US
Assignee:
Novartis AG - Basel
International Classification:
C07D 239/42
US Classification:
514256, 544329
Abstract:
Benzamide combounds of Formula I:.

5-Membered Heterocycle-Based P38 Kinase Inhibitors

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US Patent:
7863314, Jan 4, 2011
Filed:
Jun 25, 2004
Appl. No.:
10/877534
Inventors:
Olga M. Fryszman - San Diego CA, US
Hengyuan Lang - San Diego CA, US
Jiong Lan - San Diego CA, US
Edcon Chang - San Diego CA, US
Yunfeng Fang - San Diego CA, US
Assignee:
Novartis AG - Basel
International Classification:
A01N 43/56
C07D 231/00
US Classification:
514407, 5483714
Abstract:
Provided are 5-membered heterocycle-based p38 kinase inhibitors. Further provided are pyrazole and imidazole-based p38 kinase, including p38α and p38β kinase, inhibitors. Pharmaceutical compositions containing the compounds are also provided. Methods of use of the compounds and compositions are also provided, including methods of treatment, prevention, or amelioration of one or more symptoms of p38 kinase mediated diseases and disorders, including, but not limited to, inflammatory diseases and disorders.

Pim Kinase Inhibitors And Methods Of Their Use

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US Patent:
8168794, May 1, 2012
Filed:
Feb 26, 2009
Appl. No.:
12/380458
Inventors:
Matthew Burger - Albany CA, US
Jiong Lan - Moraga CA, US
Mika Lindvall - Oakland CA, US
Gisele Nishiguchi - Albany CA, US
Michelle Tetalman - Oakland CA, US
Assignee:
Novartis AG - Basel
International Classification:
A61K 31/4545
C07D 213/75
C07D 417/12
C07D 413/14
US Classification:
5462707, 546193, 514318, 514342
Abstract:
The present invention relates to new compounds of Formulas I and II, their tautomers, stereoisomers and polymorphs, and pharmaceutically acceptable salts, esters, metabolites or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the inhibition of Pim kinase activity and/or the prophylaxis or treatment of cancer.

Imidazoquinoxaline Compounds As Immunomodulators

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US Patent:
8173657, May 8, 2012
Filed:
Mar 23, 2007
Appl. No.:
12/294233
Inventors:
James Sutton - Pleasanton CA, US
Feng Xu - Walnut Creek CA, US
Nicholas Valiante - Fremont CA, US
Jiong Lan - Moraga CA, US
Assignee:
Novartis AG - Basel
International Classification:
A61K 31/50
A61K 39/02
A61K 39/12
A61K 39/00
C07D 471/00
C07D 487/00
US Classification:
514250, 544346, 544345, 544344, 4241841, 4242041, 4242341
Abstract:
The invention provides novel compositions comprising imidazoquinoxaline compounds of formula (I) and analogs thereof. Also provided are methods of administering the compositions in an effective amount to enhance the immune response of a subject. Further provided are novel compositions and methods of administering the compositions in combination with (an) other agent(s).

5-Membered Heterocycle-Based P38 Kinase Inhibitors

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US Patent:
8242117, Aug 14, 2012
Filed:
Nov 19, 2010
Appl. No.:
12/950649
Inventors:
Olga M. Fryszman - San Diego CA, US
Hengyuan Lang - San Diego CA, US
Jiong Lan - Emeryville CA, US
Edcon Chang - San Diego CA, US
Yunfeng Fang - San Diego CA, US
Assignee:
Novartis AG - Basel
International Classification:
A61K 31/5355
A61K 31/415
A61K 31/4164
A61K 31/4245
A61K 31/4439
A61K 31/506
A61K 31/497
A61P 13/00
A61P 9/00
A61P 11/06
A61P 25/28
A61P 31/12
A61P 1/00
US Classification:
5142365, 51425405, 514256, 514341, 514364, 514386, 514407
Abstract:
Provided are 5-membered heterocycle-based p38 kinase inhibitors. Further provided are pyrazole and imidazole-based p38 kinase, including p38α and p38β kinase, inhibitors. Pharmaceutical compositions containing the compounds are also provided. Methods of use of the compounds and compositions are also provided, including methods of treatment, prevention, or amelioration of one or more symptoms of p38 kinase mediated diseases and disorders, including, but not limited to, inflammatory diseases and disorders.
Jiong Lan from Moraga, CA, age ~52 Get Report