Jerome J Zalipsky

43872255, Jun 7, 1983

May 12, 1981

6/262809

George H. Douglas - Malvern PA
William L. Studt - Harleysville PA
Chong M. Won - Warrington PA
Stuart A. Dodson - Lansdale PA
Jerome J. Zalipsky - Melrose Park PA

William H. Rorer, Inc. - Fort Washington PA

C07D40106
C07D40114
C07D41714
C07D41314

544212

Heterocyclic alkyl s-triazine compounds are prepared from the corresponding amidinourea and amidinothiourea compounds by reacting with an activated form of an acid amide to give respectively substituted s-triazinones and thiones of the formula ##STR1## which have pharmacological properties that render them suitable for use for a variety of medicinal purposes, including use as antidiarrheal agents, and which are also useful derivatives in analyzing for the corresponding amidinourea or amidinothiourea precursors.

41171659, Sep 26, 1978

Nov 5, 1975

5/628857

Julius Diamond - Morris Plains NJ
Jerome J. Zalipsky - Melrose Park PA

William H. Rorer, Inc. - Fort Washington PA

A61K 3117
C07C12719

424322

This invention describes novel chemical compounds which are 1-amidino-3-phenylureas. The method of preparing these compounds and their pharmaceutical uses is also disclosed.

41839560, Jan 15, 1980

Oct 17, 1977

5/842994

Julius Diamond - Morris Plains NJ
Jerome J. Zalipsky - Melrose Park PA

William H. Rorer, Inc. - Fort Washington PA

A61K 3117

424322

This invention describes novel chemical compounds which are 1-amidino-3-phenylureas. The method of preparing these compounds and their pharmaceutical uses is also disclosed.

42253152, Sep 30, 1980

Nov 13, 1978

5/960070

Chong M. Won - Warrington PA
Jerome J. Zalipsky - Melrose Park PA
Dahyabhai M. Patel - Ambler PA

William H. Rorer, Inc. - Fort Washington PA

G01N 3106
G01N 3316

23230PC

Novel s-triazine compounds are prepared as derivatives of the corresponding amidinourea and amidinothiourea compounds by reacting with an activated form of an acid amide to give substituted s-triazinones and thiones respectively, of the formula ##STR1## The s-triazinones and thiones are useful derivatives in analyzing for the corresponding amidinourea or amidino thiourea precursors and also have useful pharmacological properties which make them suitable for a variety of medicinal purposes including use as antidiarrheal agents.

44529805, Jun 5, 1984

Jul 1, 1982

6/394128

George H. Douglas - Malvern PA
William L. Studt - Harleysville PA
Chong M. Won - Warrington PA
Stuart A. Dodson - Lansdale PA
Jerome J. Zalipsky - Melrose Park PA

William H. Rorer, Inc. - Fort Washington PA

C07D25142
C07D25116

544211

Novel s-triazine compounds are prepared as derivatives of the corresponding amidinourea and amidinothiourea compounds by reacting with an activated form of an acid amide to give substituted s-triazinones and thiones respectively, of the formula ##STR1## The s-triazinones and thiones are useful derivatives in analyzing for the corresponding amidinourea or amidino thiourea precursors and also have useful pharmacological properties which make them suitable for a variety of medicinal purposes including use as antidiarrheal agents.

42464099, Jan 20, 1981

Nov 13, 1978

5/959611

George H. Douglas - Malvern PA
William L. Studt - Harleysville PA
Chong M. Won - Warrington PA
Stuart A. Dodson - Lansdale PA
Jerome J. Zalipsky - Melrose Park PA

William H. Rorer, Inc. - Fort Washington PA

C07D25142
C07D41704
C07D41304
C07D41314

544211

Novel s-triazine compounds are prepared as derivatives of the corresponding amidinourea and amidinothiourea compounds by reacting with an activated form of an acid amide to give substituted s-triazinones and thiones respectively, of the formula ##STR1## The s-triazinones and thiones are useful derivatives in analyzing for the corresponding amidinourea or amidino thiourea precursors and also have useful pharmacological properties which make them suitable for a variety of medicinal purposes including use as antidiarrheal agents.

42195675, Aug 26, 1980

Apr 24, 1978

5/899672

Julius Diamond - Morris Plains NJ
Jerome J. Zalipsky - Melrose Park PA

William H. Rorer, Inc. - Fort Washington PA

A61K 3117

424322

This invention describes novel chemical compounds which are 1-amidino-3-phenylureas. The method of preparing these compounds and their pharmaceutical uses is also disclosed.

42162300, Aug 5, 1980

Jul 19, 1978

5/926053

Julius Diamond - Morris Plains NJ
Jerome J. Zalipsky - Melrose Park PA

William H. Rorer, Inc. - Fort Washington PA

A61K 3117

424322

This invention describes novel chemical compounds which are 1-amidino-3-phenylureas. The method of preparing these compounds and their pharmaceutical uses is also disclosed.