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Jeremy M Travins

from Southborough, MA
Age ~53

Jeremy Travins Phones & Addresses

  • 59 Flagg Rd, Southborough, MA 01772 (508) 281-0228
  • 14 Overlook Dr, Southborough, MA 01772 (508) 281-0228
  • 380 Township Line Rd, Downingtown, PA 19335 (484) 341-8377 (610) 269-8197
  • 2703 Cornell Ct, Newtown Square, PA 19073 (610) 578-9118
  • Chester Springs, PA
  • 51 Craig Ave, Madison, WI 53705 (608) 232-1498
  • Charlottesville, VA
  • Chester, PA
  • 14 Overlook Dr, Southborough, MA 01772 (484) 341-8377

Work

Company: Takeda pharmaceuticals Jan 2019 Position: Director of chemistry

Education

School / High School: University of Wisconsin - Madison 1999 to 2001 Specialities: Chemistry

Skills

Drug Design • Chemistry • Medicinal Chemistry • Drug Discovery • Drug Development • Organic Synthesis • Lead Change • Organic Chemistry • Pharmaceutical Industry • Cancer • Lc Ms • Adme • Nmr • Hplc • Chromatography • Oncology • Mass Spectrometry • Parallel Synthesis • High Throughput Screening • Uv/Vis • Lifesciences • Heterocyclic Chemistry • Kinases • Drug Metabolism • Chemdraw • Ir • Scifinder • Pharmacokinetics • Synthetic Organic Chemistry

Industries

Pharmaceuticals

Resumes

Resumes

Jeremy Travins Photo 1

Director Of Chemistry

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Location:
59 Flagg Rd, Southborough, MA 01772
Industry:
Pharmaceuticals
Work:
Takeda Pharmaceuticals
Director of Chemistry

Shire
Director; Head of Discovery Chemistry

Shire Sep 2016 - Apr 2018
Director; Discovery Chemistry Program Lead

Agios Pharmaceuticals Oct 2014 - Sep 2016
Director of Chemistry

Agios Pharmaceuticals Mar 2012 - Sep 2014
Associate Director, Chemistry
Education:
University of Wisconsin - Madison 1999 - 2001
University of Virginia 1993 - 1999
Doctorates, Doctor of Philosophy, Organic Chemistry
State University of New York College at Oswego 1989 - 1993
Bachelors, Bachelor of Science, Chemistry
Skills:
Drug Design
Chemistry
Medicinal Chemistry
Drug Discovery
Drug Development
Organic Synthesis
Lead Change
Organic Chemistry
Pharmaceutical Industry
Cancer
Lc Ms
Adme
Nmr
Hplc
Chromatography
Oncology
Mass Spectrometry
Parallel Synthesis
High Throughput Screening
Uv/Vis
Lifesciences
Heterocyclic Chemistry
Kinases
Drug Metabolism
Chemdraw
Ir
Scifinder
Pharmacokinetics
Synthetic Organic Chemistry

Publications

Us Patents

Thiophene Amidines, Compositions Thereof, And Methods Of Treating Complement-Mediated Diseases And Conditions

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US Patent:
7109354, Sep 19, 2006
Filed:
May 28, 2003
Appl. No.:
10/445817
Inventors:
Nalin Subasinghe - West Chester PA, US
Ehab Khalil - West Chester PA, US
Kristi Leonard - West Chester PA, US
Farah Ali - Exton PA, US
Heather Rae Hufnagel - Glenmoore PA, US
Jeremy M. Travins - Newtown Square PA, US
Shelley K. Ballentine - Lansdale PA, US
Kenneth T. Wilson - West Grove PA, US
Maxwell D. Cummings - Wayne PA, US
Wenxi Pan - Glenmoore PA, US
Joan Gushue - Collegeville PA, US
Sanath Meegalla - Boothwyn PA, US
Mark Wall - Harleysville PA, US
Jinsheng Chen - Exton PA, US
M. Jonathan Rudolph - Exton PA, US
Hui Huang - Belle Mead NJ, US
Assignee:
3-Dimensional Pharmaceuticals, Inc. - Yardley PA
International Classification:
C07D 333/02
C07D 333/32
US Classification:
549 29, 549 64, 549 70, 549 83
Abstract:
Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula I.

Thiophene Amidines, Compositions Thereof, And Methods Of Treating Complement-Mediated Diseases And Conditions

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US Patent:
7138530, Nov 21, 2006
Filed:
May 28, 2003
Appl. No.:
10/515554
Inventors:
Nalin Subasinghe - West Chester PA, US
Ehab Khalil - West Chester PA, US
Kristi A. Leonard - West Chester PA, US
Farah Ali - Exton PA, US
Heather Hufnagel - Glenmoore PA, US
Jeremy M. Travins - Newtown Square PA, US
Shelley K. Ballentine - Lansdale PA, US
Kenneth T. Wilson - Media PA, US
Maxwell D. Cummings - Wayne PA, US
Wenxi Pan - Glenmoore PA, US
Joan Gushue - Collegeville PA, US
Sanath Meegalla - Boothwyn PA, US
Mark Wall - Harleysville PA, US
Jinsheng Chen - Exton PA, US
Jonathan M. Rudolph - Doylestown PA, US
Hui Huang - Belle Meade NJ, US
Assignee:
3-Dimensional Pharmaceuticals, Inc. - Yardley PA
International Classification:
C07D 333/32
A61K 31/38
US Classification:
549 65, 514445
Abstract:
Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula (I) or a solvate, hydrate or pharmaceutically acceptable salt thereof; wherein R, R, R, Rand Rare defined in the specification, Z is SO or SO, and Ar is an aromatic or heteroaromatic group as defined herein.

Thiophene Sulfoximines, Compositions Thereof, And Methods Of Treating Complement-Mediated Diseases And Conditions

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US Patent:
7385066, Jun 10, 2008
Filed:
Mar 14, 2006
Appl. No.:
11/375503
Inventors:
Nalin L. Subasinghe - Exton PA, US
Shelley Ballentine - Lansdale PA, US
Jeremy M. Travins - Downingtown PA, US
Ehab M. Khalil - West Chester PA, US
Farah Ali - Exton PA, US
Kristi A. Leonard - West Chester PA, US
Joan M. Gushue - Harleysville PA, US
Michael Peter Winters - Morgantown PA, US
Heather Hufnagel - Glenmoore PA, US
Maxwell David Cummings - Strafford PA, US
Assignee:
Janssen Pharmaceutica N.V. - Beerse
International Classification:
C07D 333/34
US Classification:
549 66
Abstract:
Disclosed are compounds for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade. The compounds are of Formula I.

Conjugated Complement Cascade Inhibitors

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US Patent:
7482376, Jan 27, 2009
Filed:
Jun 16, 2004
Appl. No.:
10/869430
Inventors:
Nalin Subasinghe - West Chester PA, US
Ehab Khalil - West Chester PA, US
Farah Ali - Exton PA, US
Heather Rae Hufnagel - Glenmoore PA, US
Shelley Ballentine - Lansdale PA, US
Jeremy M. Travins - Newtown Square PA, US
Kristi A. Leonard - West Chester PA, US
Roger F. Bone - Bridgewater NJ, US
Assignee:
3-Dimensional Pharmaceuticals, Inc. - Exton PA
International Classification:
A61K 31/381
C07D 333/10
US Classification:
514445, 549 29, 549 59, 549 62, 549 65, 514438, 514444
Abstract:
The present invention is directed to conjugated complement cascade inhibitors, and a method of treating a patient using a conjugated complement cascade inhibitor.

Thiophene Sulfoximines, Compositions Thereof, And Methods Of Treating Complement-Mediated Diseases And Conditions

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US Patent:
7868023, Jan 11, 2011
Filed:
Apr 3, 2008
Appl. No.:
12/061873
Inventors:
Nalin L. Subasinghe - Exton PA, US
Shelley Ballentine - Lansdale PA, US
Jeremy M. Travins - Downingtown PA, US
Ehab M. Khalil - West Chester PA, US
Farah Ali - Exton PA, US
Kristi A. Leonard - West Chester PA, US
Joan M. Gushue - Harleysville PA, US
Michael Peter Winters - Morgantown PA, US
Heather Hufnagel - Glenmoore PA, US
Maxwell David Cummings - Strafford PA, US
Assignee:
Janssen Pharmaceutica NV
International Classification:
A61K 31/381
A61K 31/44
C07D 409/12
US Classification:
514334, 514444, 5462804, 549 59
Abstract:
Disclosed are compounds for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade. The compounds are of Formula I.

Triazolopyridazines As Kinase Modulators

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US Patent:
8030305, Oct 4, 2011
Filed:
Dec 18, 2006
Appl. No.:
11/612020
Inventors:
Tianbao Lu - Churchville PA, US
Richard Alexander - Newark DE, US
Richard W. Connors - Harleysville PA, US
Maxwell D. Cummings - Wayne PA, US
Robert A. Galemmo - Paoli PA, US
Heather Rae Hufnagel - Glenmoore PA, US
Dana L. Johnson - Upper Black Eddy PA, US
Ehab Khalil - West Chester PA, US
Kristi A. Leonard - Flourtown PA, US
Thomas P. Markotan - Morgantown PA, US
Anna C. Maroney - Media PA, US
Jan L. Sechler - Doylestown PA, US
Jeremy M. Travins - Downingtown PA, US
Robert W. Tuman - Chalfont PA, US
Assignee:
Janssen Pharmaceutica N.V.
International Classification:
C07D 487/04
A61K 31/5025
A61P 35/00
US Classification:
514248, 544236
Abstract:
The invention is directed to triazolopyridazine compounds of Formula I:.

Triazolopyridazine Compounds

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US Patent:
8173654, May 8, 2012
Filed:
Aug 7, 2008
Appl. No.:
12/187524
Inventors:
Tianbao Lu - Churchville PA, US
Richard Alexander - Newark DE, US
Richard W. Connors - Harleysville PA, US
Maxwell D. Cummings - Wayne PA, US
Robert A. Galemmo - Paoli PA, US
Heather Rae Hufnagel - Glenmoore PA, US
Dana L. Johnson - Upper Black Eddy PA, US
Ehab Khalil - West Chester PA, US
Kristi A. Leonard - Flourtown PA, US
Thomas P. Markotan - Morgantown PA, US
Anna C. Maroney - Media PA, US
Jan L. Sechler - Doylestown PA, US
Jeremy M. Travins - Downingtown PA, US
Robert W. Tuman - Chalfont PA, US
Assignee:
Janssen Pharmaceutica N.V. - Beerse
International Classification:
A61K 31/4985
C07D 487/04
A61P 3/10
A61P 17/06
A61P 25/18
A61P 19/02
A61P 9/10
A61P 9/00
A61P 35/00
US Classification:
514248, 544236
Abstract:
The invention is directed to triazolopyridazine compounds of Formula I:.

Quinazoline Compounds

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US Patent:
20100273816, Oct 28, 2010
Filed:
May 15, 2008
Appl. No.:
12/600737
Inventors:
Ronald Charles Bernotas - Royersford PA, US
John William Ullrich - Downingtown PA, US
Jeremy Mark Travins - Downingtown PA, US
Jay Edward Wrobel - Lawrenceville NJ, US
Rayomand Jal Unwalla - Eagleville PA, US
International Classification:
A61K 31/517
C07D 239/74
A61P 9/00
A61P 25/28
A61P 3/10
A61P 29/00
A61P 1/16
A61P 19/02
A61P 9/10
A61P 19/04
A61P 17/00
A61P 3/04
US Classification:
5142661, 544283
Abstract:
Disclosed are quinazoline-based modulators of Liver X receptors (LXRs) and related methods. The modulators include compounds of formula (I):
Jeremy M Travins from Southborough, MA, age ~53 Get Report