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Jehan F Bagli

from Princeton, NJ
Age ~96

Jehan Bagli Phones & Addresses

  • 61 Sayre Dr, Princeton, NJ 08540 (732) 520-0674
  • Cape Coral, FL
  • Boston, MA
  • Brookline, MA

Publications

Us Patents

Tricyclic Vasopressin Agonists

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US Patent:
6511974, Jan 28, 2003
Filed:
Jul 24, 1998
Appl. No.:
09/122020
Inventors:
John P. Dusza - Nanuet NY
Peter S. Chan - Monmouth Junction NJ
Jay D. Albright - Nanuet NY
Jehan F. Bagli - Princeton NJ
Amedeo A. Failli - Princeton NJ
Mark A. Ashwell - Plainsboro NJ
Albert J. Molinari - Princeton NJ
Thomas J. Caggiano - Morrisville PA
Eugene J. Trybulski - Princeton Junction NJ
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 3155
US Classification:
514220, 514 63, 540558, 540561, 540562, 540565
Abstract:
This invention relates to new compounds selected from those of the general formula (I), or a pharmaceutically acceptable salt, ester or prodrug form thereof: wherein D, E and G are N or CH, which serve as vasopressin agonists and are useful in treating disorders such as diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, bleeding and coagulation disorders, and the inability to temporarily delay urination and pharmaceutical compositions and methods for same.

Substituted Arylsulfonamides And Benzamides

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US Patent:
51497000, Sep 22, 1992
Filed:
Oct 30, 1991
Appl. No.:
7/785136
Inventors:
John W. Ellingboe - Princeton NJ
Jehan F. Bagli - Princeton NJ
Michael W. Winkley - St. Albans VT
Assignee:
American Home Products Corporation - New York NY
International Classification:
A61K 31505
A61K 3147
C07D32902
C07D40100
US Classification:
514275
Abstract:
This invention relates to substituted arylsulfonamides and benzamides possessing aniarrhythmic activity, to pharmaceutical compositions and to methods for production thereof.

3-Carboxamide Derivatives Of 5H-Pyrrolo?2,1-C!?1,4!-Benzodiazepines

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US Patent:
58801227, Mar 9, 1999
Filed:
Oct 22, 1997
Appl. No.:
8/955511
Inventors:
Eugene J. Trybulski - Princeton Junction NJ
Albert J. Molinari - Princeton NJ
Jehan F. Bagli - Princeton NJ
Mark A. Ashwell - Plainsboro NJ
Thomas J. Caggiano - Morrisville PA
Assignee:
American Home Products Corporation - Madison NJ
International Classification:
A61K 3155
C07D48712
US Classification:
514220
Abstract:
This invention relates to tricyclic non-peptide vasopressin antagonists which are useful in treating conditions where decreased vasopressin levels are desired, such as in congestive heart failure, in disease conditions with excess renal water reabsorption and in conditions with increased vascular resistance and coronary vasoconstriction, the compounds having the general structure: ##STR1##.

5-Substituted-6-Aminopyrimidine Derivatives

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US Patent:
50029495, Mar 26, 1991
Filed:
May 1, 1990
Appl. No.:
7/517099
Inventors:
Steven M. Peseckis - Plainsboro NJ
Jehan F. Bagli - Princeton NJ
Richard J. Heaslip - Newtown PA
Thomas J. Colatsky - Devon PA
Assignee:
American Home Products Corporation - New York NY
International Classification:
A61K 31505
C07D23902
US Classification:
514256
Abstract:
A compound of the formula: ##STR1## in which R. sup. 1 is --OH or --NH. sub. 2 ; R. sup. 2 is a halogen or --CN; R. sup. 3 is a halogen or --CN; and n is one of the integers 1, 2 or 3; or a pharmaceutically acceptable salt thereof, are useful as antithrombotic agents.

Preparation Of 2,6-Disubstituted-5-Cyano-4-Pyrimidinyloxyacetic Acid Aldose Reductase Inhibitors

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US Patent:
49067532, Mar 6, 1990
Filed:
Jul 20, 1988
Appl. No.:
7/221586
Inventors:
Jehan F. Bagli - Princeton NJ
John W. Ellingboe - Princeton NJ
Thomas R. Alessi - Flemington NJ
Assignee:
American Home Products Corporation - New York NY
International Classification:
C07D23902
US Classification:
544319
Abstract:
Disclosed herein are 2,6-disubstituted-5-cyano-4-pyrimidinyloxyacetic acids and pharmaceutically acceptable salts thereof and methods of their preparation. The compounds are new aldose reductase inhibitors useful for the treatment of prevention of diabetic complications.

Aminopyrimidine Derivatives As Antiviral Agents For Respiratory Syncytial Virus

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US Patent:
52566684, Oct 26, 1993
Filed:
Mar 17, 1993
Appl. No.:
8/032065
Inventors:
Daniel M. Teller - Columbus OH
Alan R. Davis - Wayne PA
Michael D. Lubeck - Glenmoore PA
Jehan F. Bagli - Princeton NJ
Assignee:
American Home Products Corporation - New York NY
International Classification:
A61K 31505
US Classification:
514269
Abstract:
Antiviral activity against respiratory syncytial virus has been found in some substituted 6-aminopyrimidines having the formula: ##STR1## wherein R. sup. 1 is lower alkyl, preferably methyl or t-butyl, R. sup. 2 is halogen or cyano, and R. sup. 3 is C. sub. 1 -C. sub. 6 alkyl or --(CH. sub. 2). sub. n R. sup. 4 where n is 1 or 2 and R. sup. 4 is phenyl, phenyl substituted by lower alkoxy, lower alkyleneoxy, bromo, or 3,4-methylenedioxy; 3 or 4-pyridinyl, pyridinyl substituted by cyano or bromo, thienyl, or di-(C. sub. 1 -C. sub. 6 alkyl)amino.

2,4-Disubstituted-5-Cyano-1,6-Dihydro-6-Oxo-1-Pyrimidineacetic Acid Aldose Reductase Inhibitors

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US Patent:
49008293, Feb 13, 1990
Filed:
Jul 20, 1988
Appl. No.:
7/221588
Inventors:
Jehan F. Bagli - Princeton NJ
John W. Ellingboe - Princeton NJ
Thomas R. Alessi - Flemington NJ
Assignee:
American Home Products Corporation - New York NY
International Classification:
C07D23922
US Classification:
544319
Abstract:
Disclosed herein are 2,4-disubstituted-5-cyano-1,6-dihydro-6-oxo-1-pyrimidineacetic acids and pharmaceutically acceptable salts thereof and methods of their preparation. The compounds are new aldose reductase inhibitors useful for the treatment or prevention of diabetic complications.

2,4-Disubstituted-5-Cyano-1,6-Dihydro-6-Oxo-1-Pyrimidineacetic Acid Aldose Reductase Inhibitors

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US Patent:
47866381, Nov 22, 1988
Filed:
Jun 12, 1987
Appl. No.:
7/061831
Inventors:
Jehan F. Bagli - Princeton NJ
John W. Ellingboe - Princeton NJ
Thomas R. Alessi - Flemington NJ
Assignee:
American Home Products Corporation - New York NY
International Classification:
A61K 31495
A61K 31505
C07D40304
C07D40104
US Classification:
514252
Abstract:
Disclosed herein are 2,4-disubstituted-5-cyano-1,6-dihydro-6-oxo-1-pyrimidineacetic acids and pharmaceutically acceptable salts thereof and methods of their preparation. The compounds are new aldose reductase inhibitors useful for the treatment or prevention of diabetic complications.
Jehan F Bagli from Princeton, NJ, age ~96 Get Report