Search

Jeffrey Colbeck Phones & Addresses

  • Milwaukee, WI
  • 934 Nantasket Ave, Hull, MA 02045 (781) 925-1490
  • Menlo Park, CA
  • Julian, PA
  • 9579 N Lake Dr, Milwaukee, WI 53217

Publications

Us Patents

Combined Automated Parallel Synthesis Of Polynucleotide Variants

View page
US Patent:
8383346, Feb 26, 2013
Filed:
Sep 18, 2009
Appl. No.:
12/562988
Inventors:
Jeffrey Colbeck - Menlo Park CA, US
Benjamin Mijts - Belmont CA, US
Lorraine Joan Giver - Sunnyvale CA, US
Richard J. Fox - Kirkwood MO, US
Vesna Mitchell - San Jose CA, US
Bumshik Robert Pak - Fremont CA, US
Lynne Gilson - Encinitas CA, US
Assignee:
Codexis, Inc. - Redwood City CA
International Classification:
C12Q 1/68
C12P 19/34
C07H 21/04
US Classification:
435 612, 536 2433, 435 912
Abstract:
The present disclosure relates to methods for efficient synthesis, cloning, transformation and screening of large diverse libraries of polynucleotide variants comprising well-defined nucleotide differences relative to a reference polynucleotide.

Biocatalytic Processes For The Preparation Of Stereomerically Pure Fused Bicyclic Proline Compounds

View page
US Patent:
8574876, Nov 5, 2013
Filed:
Mar 30, 2012
Appl. No.:
13/436506
Inventors:
Benjamin Mijts - Belmont CA, US
Sheela Muley - Fremont CA, US
Jack Liang - San Mateo CA, US
Lisa M. Newman - San Jose CA, US
Xiyun Zhang - Fremont CA, US
James Lalonde - Palo Alto CA, US
Michael D. Clay - Menlo Park CA, US
Jun Zhu - Shanghai, CN
John M. Gruber - El Dorado Hills CA, US
Jeffrey Colbeck - Menlo Park CA, US
Jagadeesh Mavinahalli - Singapore, SG
Roger Sheldon - Hoog Keppel, NL
Assignee:
Codexis, Inc. - Redwood City CA
International Classification:
C12P 7/62
C12P 13/22
US Classification:
435135, 435108
Abstract:
The present disclosure provides substantially enantiomerically pure heterobicyclic compounds of the following structural formulas,.

Method Of Synthesizing Polynucleotide Variants

View page
US Patent:
20090312196, Dec 17, 2009
Filed:
Jun 11, 2009
Appl. No.:
12/483089
Inventors:
Jeffrey Colbeck - Menlo Park CA, US
Benjamin Mijts - Belmont CA, US
Lorraine Joan Giver - Sunnyvale CA, US
Richard J. Fox - Kirkwood MO, US
Assignee:
CODEXIS, INC. - Redwood City CA
International Classification:
C40B 40/06
C12P 19/34
C40B 50/06
US Classification:
506 16, 435 911, 435 912, 506 26
Abstract:
The present disclosure relates to methods for generating libraries of polynucleotide variants comprising defined nucleotide differences relative to a reference polynucleotide.

Biocatalytic Processes For The Preparation Of Substantially Stereomerically Pure Fused Bicyclic Proline Compounds

View page
US Patent:
20100063300, Mar 11, 2010
Filed:
Jun 23, 2009
Appl. No.:
12/490190
Inventors:
Benjamin Mijts - Belmont CA, US
Sheela Muley - Fremont CA, US
Jack Liang - San Mateo CA, US
Lisa M. Newman - San Jose CA, US
Xiyun Zhang - Fremont CA, US
James Lalonde - Palo Alto CA, US
Michael D. Clay - Menlo Park CA, US
Jun Zhu - Sunnyvale CA, US
John M. Gruber - El Dorado Hills CA, US
Jeffrey Colbeck - Menlo Park CA, US
Jagadeesh Mavinahalli - Singapore, SG
Roger Sheldon - Hoog Keppel, NL
Assignee:
Codexis, Inc. - Redwood City CA
International Classification:
C07D 209/52
US Classification:
548452
Abstract:
The present disclosure provides substantially enantiomerically pure heterobicyclic compounds of the following structural formulas,wherein A, M, M′, and Rare as described herein, and to biocatalytic processes for their preparation, and to the enzymes used in those processes.

Stereomerically Pure Fused Bicyclic Proline Compounds Useful For Preparing Hepatitis C Protease Inhibitors

View page
US Patent:
20120130087, May 24, 2012
Filed:
Nov 11, 2011
Appl. No.:
13/294930
Inventors:
Benjamin Mijts - Belmont CA, US
Sheela Muley - Fremont CA, US
Jack Liang - San Mateo CA, US
Lisa M. Newman - San Jose CA, US
Xiyun Zhang - Fremont CA, US
James Lalonde - Palo Alto CA, US
Michael D. Clay - Menlo Park CA, US
Jun Zhu - Shanghai, CN
John M. Gruber - El Dorado Hills CA, US
Jeffrey Colbeck - Menlo Park CA, US
Jagadeesh Mavinahalli - Singapore, SG
Roger Sheldon - Hoog Keppel, NL
Assignee:
CODEXIS, INC. - Redwood City CA
International Classification:
C07D 209/52
C07D 487/14
US Classification:
548418, 548512, 548452
Abstract:
The present disclosure provides substantially enantiomerically pure heterobicyclic compounds of the following structural formulas,wherein A, M, M′, and Rare as described herein, and to biocatalytic processes for their preparation, and to the enzymes used in those processes.

Lantibiotic Variants And Uses Thereof

View page
US Patent:
20190315814, Oct 17, 2019
Filed:
Jul 14, 2017
Appl. No.:
16/316328
Inventors:
- Blacksburg VA, US
Johan Anthony KERS - Wellesley MA, US
Sheela MULEY - Fremont CA, US
Melissa MAYO - Foster City CA, US
Jeffrey COLBECK - Belmont CA, US
Robert Eryl SHARP - Belmont CA, US
Anthony W. DEFUSCO - Newberry FL, US
International Classification:
C07K 14/315
A61K 45/06
A61K 38/16
A61K 9/68
A61Q 11/00
A61K 9/00
A01N 63/02
A61P 31/04
A61K 8/64
Abstract:
The disclosure relates to lantibiotic structural variants that have improved antimicrobial properties when compared to wild-type lantibiotics, and uses thereof. Embodiments include non-naturally occurring lantibiotics.
Jeffrey C Colbeck from Milwaukee, WI Get Report