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Janos S Pitlik

from Worcester, MA
Age ~61
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Also known as:
Janos Pitik, Pitlik Janos, Janos C
Phone and address:
26 Old Lincoln St APT 7, Worcester, MA 01605
(508) 799-3988
Related to:
Peter D Pitlik, 33
Connected to:
Amy Pitlik, 44Jaime E Pitliuk, 79Allen J Pitman, 34Barbara J Pitman, 69Cara Pitman, 30Catherine A Pitman, 65Christina D Pitman, 47Danny P Pitman, 75Earl I Pitman, 68Edward J Pitman, 66

Janos Pitlik Phones & Addresses

  • 26 Old Lincoln St APT 7, Worcester, MA 01605 (508) 799-3988
  • Anaheim, CA
  • 1 Robin Rd, Westboro, MA 01581 (508) 836-0199
  • Westborough, MA
  • 207 Maple St, Needham, MA 02492
  • Rockville, MD
  • Millbury, MA
  • Cambridge, MA

Work

Company: Unemployed Jan 2004 Position: Unemployed and ssdi

Education

School / High School: Group for Antibiotics of the Hungarian Academy of Sciences, University of Debrecen 1989 Specialities: Ph.D. in Chemistry, Research

Resumes

Resumes

Janos Pitlik Photo 1

Janos Pitlik Worcester, MA

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Work:
Unemployed

Jan 2004 to 2000
Unemployed and SSDI
Surface Logics

2003 to Nov 2004
January Principal Investigator
Vertex Pharmaceuticals, Inc
Cambridge, MA
Jun 1997 to 2003
July Staff Investigator and Group Leader
Johns Hopkins University
Baltimore, MD
1994 to Oct 1997
Associate Research Scientist
Research Group for Antibiotics, Hungarian Academy of Sciences, University of Debrecen, Hungary

Sep 1990 to 1993
September Senior Research Fellow
Dyson Perrins Laboratory, University of Oxford, UK
Oxford
May 1989 to Aug 1990
Postdoctoral Research Fellow
Education:
Group for Antibiotics of the Hungarian Academy of Sciences, University of Debrecen
1989
Ph.D. in Chemistry, Research
University of Debrecen
1987
MS in Organic Chemistry

Publications

Us Patents

Inhibitors Of Serine Proteases, Particularly Hcv Ns3-Ns4A Protease

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US Patent:
7109172, Sep 19, 2006
Filed:
Jul 16, 2004
Appl. No.:
10/893748
Inventors:
Shawn D. Britt - Andover MA, US
Kevin M. Cottrell - Cambridge MA, US
Robert B. Perni - Marlborough MA, US
Janos Pitlik - Westborough MA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
A61K 38/00
US Classification:
514 18
Abstract:
The present invention relates to compounds of formula I or formula Ia or pharmaceutically acceptable salts thereof, that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3–NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are useful as antiviral agents. The invention further relates to pharmaceutically acceptable compositions comprising said compounds either for ex vivo use or for administration to a patient suffering from HCV infection and processes for preparing the compounds. The invention also relates to methods of treating an HCV infection in a patient by administering a pharmaceutical composition comprising a compound of this invention.

Inhibitors Of Serine Proteases, Particularly Hcv Ns3-Ns4A Proteases

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US Patent:
7208600, Apr 24, 2007
Filed:
Oct 12, 2004
Appl. No.:
10/964214
Inventors:
Kevin M. Cottrell - Cambridge MA, US
Robert B. Perni - Marlborough MA, US
Janos Pitlik - Westborough MA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
C07D 241/10
A61K 31/495
US Classification:
544406, 544405, 548523, 51425501, 514422
Abstract:
The present invention relates to compounds of formula I:.

Inhibitors Of Serine Proteases, Particularly Hcv Ns3-Ns4A Protease

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US Patent:
7241796, Jul 10, 2007
Filed:
Oct 24, 2002
Appl. No.:
10/280940
Inventors:
Luc J. Farmer - Foxboro MA, US
Robert B. Perni - Marlborough MA, US
Janos Pitlik - Westborough MA, US
John H. van Drie, Jr. - Andover MA, US
Assignee:
Vertex Pharmaceuticals Inc. - Cambridge MA
International Classification:
A61K 31/40
A01N 43/38
C07D 209/56
C07D 487/00
C07D 491/00
US Classification:
514411, 514410, 514 19, 548424, 548429, 548430
Abstract:
The present invention relates to peptidomimetic compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3–NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention.

Inhibitors Of Serine Proteases, Particularly Hcv Ns3-Ns4A Protease

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US Patent:
7273885, Sep 25, 2007
Filed:
Apr 11, 2003
Appl. No.:
10/412600
Inventors:
Janos Pitlik - Westborough MA, US
Kevin M. Cottrell - Cambridge MA, US
Luc J. Farmer - Foxboro MA, US
Robert B. Perni - Marlborough MA, US
Lawrence F. Courtney - Medway MA, US
John H. van Drie - Andover MA, US
Mark A. Murcko - Holliston MA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
A61K 31/403
A61K 31/435
C07D 209/02
C07D 221/00
US Classification:
514414, 546 79, 546 85, 546112, 548134, 548146, 548182, 548225, 548250, 5482622, 548452, 548465, 514292, 514299
Abstract:
The present invention relates to compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention. The invention further relates to processes for preparing these compounds.

Inhibitors Of Serine Proteases, Particularly Hcv Ns3-Ns4A Protease

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US Patent:
7365092, Apr 29, 2008
Filed:
Apr 9, 2004
Appl. No.:
10/821663
Inventors:
Kevin M. Cottrell - Cambridge MA, US
John Maxwell - Quincy MA, US
Robert B. Perni - Marlborough MA, US
Janos Pitlik - Westborough MA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
A61K 31/4025
C07D 207/30
US Classification:
514422, 548413, 548517, 548518, 5462681, 5462764, 544224, 544242, 514408, 514423
Abstract:
The present invention relates to compounds of formula I:.

Inhibitors Of Serine Proteases, Particularly Hcv Ns3-Ns4A Protease

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US Patent:
7378422, May 27, 2008
Filed:
Sep 7, 2004
Appl. No.:
10/936450
Inventors:
Robert B. Perni - Marlborough MA, US
John J. Court - Littleton MA, US
Shawn D. Britt - Andover MA, US
Janos Pitlik - Westborough MA, US
John H. van Drie - Andover MA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
A61K 31/517
A61K 31/497
C07D 239/88
C07D 241/24
US Classification:
51425505, 5142662, 544284, 544357
Abstract:
The present invention relates to compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention. The invention further relates to processes for preparing these compounds.

Inhibitors Of Serine Proteases, Particularly Hcv Ns3-Ns4A Protease

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US Patent:
7683033, Mar 23, 2010
Filed:
Feb 4, 2005
Appl. No.:
11/051977
Inventors:
Kevin M. Cottrell - Cambridge MA, US
John J. Court - Littleton MA, US
David D. Deininger - Arlington MA, US
Luc J. Farmer - Foxboro MA, US
Janos Pitlik - Westborough MA, US
Robert B. Permi - Marlborough MA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
A61K 38/07
A61K 39/42
US Classification:
514 18, 530330, 4241491
Abstract:
The present invention relates to compounds of formula I:.

Inhibitors Of Serine Proteases, Particularly Hcv Ns3-Ns4A Protease

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US Patent:
7745444, Jun 29, 2010
Filed:
Apr 10, 2008
Appl. No.:
12/082668
Inventors:
Robert B. Perni - Marlborough MA, US
John J. Court - Littleton MA, US
Shawn D. Britt - Andover MA, US
Janos Pitlik - Westborough MA, US
John H. van Drie - Andover MA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
A61K 31/497
C07D 241/24
US Classification:
51425505, 51425506, 544406
Abstract:
The present invention relates to compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention. The invention further relates to processes for preparing these compounds.
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Janos S Pitlik from Worcester, MA, age ~61 Get Report