Janice L Cacace

6720003, Apr 13, 2004

Feb 16, 2001

09/785040

Chih-Ming Chen - Davie FL
Boyong Li - Davie FL
Janice Cacace - Miami FL

Andrx Corporation - Davie FL

A61K 920

424464, 424400, 424465, 424489, 514321, 514646

A process for preparing amorphous paroxetine hydrochloride or sertraline hydrochloride is provided, which comprises preparing a solution in which paroxetine hydrochloride or sertraline hydrochloride and a water-soluble polymer are dissolved in a co-solvent of a volatile organic solvent and water. Said solution is dried to obtain a composition comprising amorphous paroxetine hydrochloride or sertraline hydrochloride and the water-soluble matrix.

6964946, Nov 15, 2005

Apr 6, 1998

09/055818

Jose C. Gutierrez-Rocca - Miami FL, US
Janice L. Cacace - Miami FL, US
Sami Selim - Irvine CA, US
Robert Testman - Corona CA, US
J. Michael Rutledge - Riverdale NY, US

Baker Norton Pharmaceuticals, Inc. - Miami FL

A61K031/337

514 11, 514449

Pharmaceutical compositions for oral administration to mammalian subjects comprise a taxane or taxane derivative (e. g. , paclitaxel or docetaxel) as active ingredient and a vehicle comprising at least 30% by weight of a carrier for the taxane, said carrier having an HLB value of at least about 10. The compositions may also comprise 0–70% of a viscosity-reducing co-solubilizer. The compositions may be incorporated into conventional oral pharmaceutical dosage forms, or can be in the form of a two-part medicament wherein the first part includes the taxane in a solubilizing vehicle and the second part comprises a carrier for the taxane to promote oral absorption. Methods of treatment of taxane-responsive disease conditions employing the novel compositions are also disclosed, whereby the compositions can be administered alone or in association with an oral bioavailability enhancing agent.

8633178, Jan 21, 2014

Nov 21, 2012

13/684002

Janice Louise Cacace - Miami FL, US
Peter H. R. Persicaner - Boca Raton FL, US
Neda Irani - Palm Beach Garden FL, US
Julia M. Amadio - Boca Raton FL, US

TherapeuticsMD, Inc. - Boca Raton FL

A01N 45/00
A61K 9/48

514169, 424452

Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.

20050027011, Feb 3, 2005

Dec 23, 2003

10/746324

Chih-Ming Chen - Davie FL, US
Boyong Li - Davie FL, US
Janice Cacace - Miami FL, US

Andrx Corporation - Davie FL

A61K009/20
A61K009/14
A61K031/137

514649000, 514651000, 424486000

A process for preparing amorphous paroxetine hydrochloride or sertraline hydrochloride is provided, which comprises preparing a solution in which paroxetine hydrochloride or sertraline hydrochloride and a water-soluble polymer are dissolved in a co-solvent of a volatile organic solvent and water. Said solution is dried to obtain a composition comprising amorphous paroxetine hydrochloride or sertraline hydrochloride and the water-soluble matrix.

20050267201, Dec 1, 2005

Jun 24, 2005

11/165896

Jose Gutierrez-Rocca - Miami FL, US
Janice Cacace - Miami FL, US
Sami Selim - Irvine CA, US
Robert Testman - Miami FL, US
J. Rutledge - Riverdale NY, US

Baker Norton Pharmaceuticals, Inc. - Miami FL

A61K031/337
A61K009/20

514449000, 424464000

Pharmaceutical compositions for oral administration to mammalian subjects comprise a taxane or taxane derivative (e.g., paclitaxel or docetaxel) as active ingredient and a vehicle comprising at least 30% by weight of a carrier for the taxane, said carrier having an HLB value of at least about 10. The compositions may also comprise 0-70% of a viscosity-reducing co-solubilizer. The compositions may be incorporated into conventional oral pharmaceutical dosage forms, or can be in the form of a two-part medicament wherein the first part includes the taxane in a solubilizing vehicle and the second part comprises a carrier for the taxane to promote oral absorption. Methods of treatment of taxane-responsive disease conditions employing the novel compositions are also disclosed, whereby the compositions can be administered alone or in association with an oral bioavailability enhancing agent.

20100022634, Jan 28, 2010

Jun 15, 2009

12/456300

Steven Holmes - Tinley Park IL, US
Janice Cacace - Miami FL, US

ALPHARMA INC. - Bridgewater NJ

A61K 31/35
A61P 3/00

514456

An animal feed additive composition comprises an effective amount of a laidlomycin, a carrier, magnesium sulfate, and silicon dioxide. Other embodiments include methods of making the animal feed additive compositions, and the use of a laidlomycin in the manufacture of an animal feed additive for increasing the efficiency of feed utilization and rate of weight gain in domestic animals.

20130243853, Sep 19, 2013

May 6, 2013

13/888096

Janice CACACE - Miami FL, US
Ayalew TEFFERI - Rochester MN, US

TargeGen, Inc. - Bridgewater NJ

A61K 31/506
A61K 9/48

424452, 514275

Provided herein are compositions and methods for treating myelofibrosis in a subject. The methods comprise administering to the subject an effective amount of compound which is which is N-tert-butyl-3-[(5-methyl-2-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}pyrimidin-4-yl)amino]benzenesulfonamide or a pharmaceutical salt thereof or a hydrate thereof.

20130252988, Sep 26, 2013

May 6, 2013

13/888073

Janice CACACE - Miami FL, US
Ayalew TEFFERI - Rochester MN, US

TARGEGEN, INC. - Bridgewater NJ

A61K 31/506

514275

Provided herein are compositions and methods for treating myelofibrosis in a subject. The methods comprise administering to the subject an effective amount of compound which is which is N-tert-butyl-3-[(5-methyl-2-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}pyrimidin-4-yl)amino]benzenesulfonamide or a pharmaceutical salt thereof or a hydrate thereof.