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Gregory J Porreca

from Cambridge, MA
Age ~45
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Also known as:
Gregory Joseph Porreca
Phone and address:
57 Reservoir St #1, Cambridge, MA 02138
Related to:
Albert L Porreca, 76Albert L PorrecaJohn Lips, 67Emily C Richardson, 80Michele L Capuchino, 52Edward Penczak
Connected to:
Angela J Porreca, 53Bruno F Porreca, 61Jean K Porreca, 56John Porreca, 75Julie A Porreca, 62Kelly A Porreca, 59Lori A Porreca, 68Marc Porreca, 67Kristina L Porreco, 35Christina O Porrello, 47

Gregory Porreca Phones & Addresses

  • 57 Reservoir St #1, Cambridge, MA 02138
  • 22 Longfellow Rd, Cambridge, MA 02138
  • 30 Andrew St, Cambridge, MA 02139 (617) 864-6445
  • Carroll, NH
  • Bretton Woods, NH
  • Ocean City, NJ
  • Allston, MA
  • Ewing, NJ

Industries

Biotechnology

Resumes

Resumes

Gregory Porreca Photo 1

Founder At Good Start Genetics, Inc.

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Location:
Greater Boston Area
Industry:
Biotechnology

Publications

Us Patents

Sequence Assembly

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US Patent:
8209130, Jun 26, 2012
Filed:
Apr 4, 2012
Appl. No.:
13/439508
Inventors:
Caleb Kennedy - Arlington MA, US
Gregory J. Porreca - Cambridge MA, US
Assignee:
Good Start Genetics, Inc. - Cambridge MA
International Classification:
G06F 19/00
C12Q 1/68
US Classification:
702 20, 435 611
Abstract:
The invention relates to assembly of sequence reads. The invention provides a method for identifying a mutation in a nucleic acid involving sequencing nucleic acid to generate a plurality of sequence reads. Reads are assembled to form a contig, which is aligned to a reference. Individual reads are aligned to the contig. Mutations are identified based on the alignments to the reference and to the contig.

Polony Fluorescent In Situ Sequencing Beads

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US Patent:
20070087362, Apr 19, 2007
Filed:
Aug 16, 2006
Appl. No.:
11/505073
Inventors:
George Church - Brookline MA, US
Jay Shendure - Chagrin Falls OH, US
Gregory Porreca - Cambridge MA, US
Jun Zhu - Durham NC, US
Assignee:
President and Fellows of Harvard College - Cambridge MA
International Classification:
C40B 30/06
C40B 40/08
C12Q 1/68
C12M 1/34
US Classification:
435006000, 435287200
Abstract:
Miniaturized, high-density, bead-based arrays are provided. Methods of producing and using clonal beads and producing and using miniaturized, high density, bead-based arrays are also provided.

Wobble Sequencing

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US Patent:
20070207482, Sep 6, 2007
Filed:
Feb 2, 2007
Appl. No.:
11/670588
Inventors:
George Church - Brookline MA, US
Jay Shendure - Chagrin Falls OH, US
Gregory Porreca - Ocean City NJ, US
Assignee:
President and Fellows of Harvard College - Cambridge MA
International Classification:
C12Q 1/68
C07H 21/04
US Classification:
435006000, 536025320
Abstract:
Novel methods and compositions for DNA sequencing are provided. The methods described herein are useful for sequencing homopolymeric regions of DNA. The methods also prevent the accumulation of mistakes and inefficiencies in the sequencing reaction.

Multiplex Decoding Of Sequence Tags In Barcodes

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US Patent:
20080269068, Oct 30, 2008
Filed:
Feb 6, 2008
Appl. No.:
12/027039
Inventors:
George M. CHURCH - Brookline MA, US
Jay Shendure - Chagrin Falls OH, US
Gregory J. Porreca - Ocean City NJ, US
Nikos Reppas - Cedar Falls IA, US
Assignee:
President and Fellows of Harvard College - Cambridge MA
International Classification:
C40B 30/04
C40B 50/06
US Classification:
506 9, 506 26
Abstract:
Methods and compositions for performing multiplex reactions are provided.

Nanogrid Rolling Circle Dna Sequencing

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US Patent:
20090018024, Jan 15, 2009
Filed:
May 14, 2008
Appl. No.:
12/120541
Inventors:
George M. CHURCH - Brookline MA, US
Gregory J. Porreca - Ocean City NJ, US
Jay Shendure - Chagrin Falls OH, US
Abraham Meir Rosenbaum - Brookline MA, US
Assignee:
President and Fellows of Harvard College - Cambridge MA
International Classification:
C40B 20/00
US Classification:
506 2
Abstract:
The present invention relates to methods for sequencing a polynucleotide immobilized on an array having a plurality of specific regions each having a defined diameter size, including synthesizing a concatemer of a polynucleotide by rolling circle amplification, wherein the concatemer has a cross-sectional diameter greater than the diameter of a specific region, immobilizing the concatemer to the specific region to make an immobilized concatemer, and sequencing the immobilized concatemer.

Methods For Sequencing Dna

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US Patent:
20090318298, Dec 24, 2009
Filed:
Mar 27, 2009
Appl. No.:
12/412471
Inventors:
Jae B. Kim - Thousand Oaks CA, US
Gregory J. Porreca - Cambridge MA, US
George M. Church - Brookline MA, US
Jonathan G. Seidman - Milton MA, US
Assignee:
President and Fellows of Harvard College - Cambridge MA
Brigham and Women's Hospital, Inc. - Boston MA
International Classification:
C40B 20/00
C40B 40/08
C40B 50/18
US Classification:
506 2, 506 17, 506 32
Abstract:
The invention is directed to methods for using sequence by ligation to sequence DNA immobilized on miniaturized, high density bead-based arrays. Methods are provided to fabricate an array of beads where the beads are coupled directly to a solid support. Methods are also provided to improve signal and reduce background in ligation-mediated DNA sequencing. In addition, methods are provided to improve the accuracy of reported tag counts when performing DNA sequencing by fluorescent nonamer ligation.

Methods For Maintaining The Integrity And Identification Of A Nucleic Acid Template In A Multiplex Sequencing Reaction

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US Patent:
20120164630, Jun 28, 2012
Filed:
Apr 7, 2011
Appl. No.:
13/081660
Inventors:
Gregory Porreca - Cambridge MA, US
Mark Umbarger - Brookline MA, US
George Church - Brookline MA, US
Assignee:
GOOD START GENETICS, INC. - Boston MA
International Classification:
C12Q 1/68
US Classification:
435 61
Abstract:
The invention generally relates to methods for maintaining the integrity and identification of a nucleic acid template in a multiplex sequencing reaction. In certain embodiments, methods of the invention involve obtaining a template nucleic acid, incorporating a pair of sequence identifiers into the template, and sequencing the template.

Methods And Compositions For Evaluating Genetic Markers

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US Patent:
20120165202, Jun 28, 2012
Filed:
Apr 30, 2010
Appl. No.:
13/266862
Inventors:
Gregory Porreca - Cambridge MA, US
Uri Laserson - Boston MA, US
Jin Billy Li - Medford MA, US
E. Robert Wassman - Marblehead MA, US
Assignee:
GOOD START GENETICS, INC. - Cambridge MA
International Classification:
C40B 20/00
US Classification:
506 2
Abstract:
Aspects of the invention relates to methods and compositions that are useful to reduce bias and increase the reproducibility of multiplex analysis of genetic loci. In some configurations, predetermined preparative steps and/or nucleic acid sequence analysis techniques are used in multiplex analyses for a plurality of genetic loci in a plurality of samples.
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Gregory J Porreca from Cambridge, MA, age ~45 Get Report