US Patent:
20220233756, Jul 28, 2022
Inventors:
George A. Herzlinger - Belmont MA, US
Regina E. Herzlinger - Belmont MA, US
International Classification:
A61M 1/36
A61M 1/16
A61M 1/28
B01D 69/08
B01D 71/06
Abstract:
The present disclosure provides methods and systems for treating a biological fluid of a subject suffering from a microbial infection (e.g., a drug-resistant microbial infection). In some embodiments, these methods and systems involve a complement receptor immobilized on, or otherwise associated with a polymer substrate, for example, high surface area particles, membranes, hollow fibers, and/or other porous or non-porous media. In other embodiments, the methods and systems involve a complement receptor present in a dialysate used in a dialyzer for extracting pathogens out of a biological fluid, for example, the blood of a patient.