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Geertruida M Veldman

from Sudbury, MA
Age ~71
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Also known as:
Geertruid M Veldman
Phone and address:
60 Woodmere Dr, North Sudbury, MA 01776
Related to:
Trudi M Veldman, 42Trudi M Veldman, 56
Connected to:
Barbara G Veldman, 85Cory D Veldman, 45Dina T Veldman, 65Francis E Veldman, 74James T Veldman, 57Jessica R Veldman, 41Mark W Veldman, 49Johan G Veldsman, 56Joshua A Veldstra, 40Cesar Vele, 59

Geertruida Veldman Phones & Addresses

  • 60 Woodmere Dr, Sudbury, MA 01776
  • Worcester, MA
  • Boston, MA

Publications

Us Patents

Humanized Immunoglobulin Reactive With B7-2 And Methods Of Treatment Therewith

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US Patent:
6827934, Dec 7, 2004
Filed:
Jul 27, 2000
Appl. No.:
09/627896
Inventors:
Man Sung Co - Cupertino CA
Maximiliano Vasquez - Palo Alto CA
Beatriz Carreno - Acton MA
Abbie Cheryl Celniker - Newton MA
Mary Collins - Natick MA
Samuel Goldman - Acton MA
Andrea Knight - Hampton NH
Denise OHara - Reading MA
Bonita Rup - Reading MA
Geertruida M. Veldman - Sudbury MA
Gary S. Gray - Brookline MA
Assignee:
Genetics Institute, LLC - Cambridge MA
International Classification:
A61K 39395
US Classification:
4241531, 4241301, 4241331, 4241411, 4241431, 4241441, 4241731, 5303871, 5303873, 5303881, 5303882, 53038822, 5303887, 53038873
Abstract:
The invention relates to a humanized anti-B7-2 antibody that comprises a variable region of nonhuman origin and at least a portion of an immunoglobulin of human origin. The invention also pertains to methods of treatment for various autoimmune diseases, transplant rejection, inflammatory disorders and infectious diseases by administering humanized anti-B7-2 and/or anti-B7-1 antibodies.

Humanized Immunoglobulin Reactive With B7 Therewith

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US Patent:
6913747, Jul 5, 2005
Filed:
Jun 24, 1999
Appl. No.:
09/339596
Inventors:
Man Sung Co - Cupertino CA, US
Maximiliano Vasquez - Palo Alto CA, US
Beatriz Carreno - Acton MA, US
Abbie Cheryl Celniker - Newton MA, US
Mary Collins - Natick MA, US
Samuel Goldman - Acton MA, US
Gary S. Gray - Brookline MA, US
Andrea Knight - Hampton NH, US
Denise O'Hara - Reading MA, US
Bonita Rup - Reading MA, US
Geertruida M. Veldman - Sudbury MA, US
International Classification:
A61K039/395
C07K016/28
C12N015/13
C12N015/63
US Classification:
4241531, 4241301, 4241331, 4241411, 4241431, 4241441, 4241731, 435 696, 435325, 435326, 435328, 435332, 435343, 4353431, 435346, 4352523, 4353201, 435455, 5303871, 5303873, 5303881, 5303882, 53038822, 5303887, 53038873, 536 231, 536 235, 536 2353
Abstract:
The invention relates to humanized anti-B7-2 and anti-B7-1 antibodies, wherein each comprise a variable region of non-human origin and at least a portion of an immunoglobulin of human origin. The invention also pertains to methods of treatment for various autoimmune diseases, transplant rejection, inflammatory disorders and infectious diseases by administering humanized anti-B7-2 and/or anti-B7-1 antibodies.

Human Antibodies That Bind Human Il-12 And Methods For Producing

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US Patent:
6914128, Jul 5, 2005
Filed:
Mar 24, 2000
Appl. No.:
09/534717
Inventors:
Jochen Salfeld - North Grafton MA, US
Michael Roguska - Ashland MA, US
Michael Paskind - Sterling MA, US
Subhashis Banerjee - Shrewsbury MA, US
Daniel Tracey - Harvard MA, US
Michael White - Framingham MA, US
Zehra Kaymakcalan - Westborough MA, US
Boris Labkovsky - Marlborough MA, US
Paul Sakorafas - Newton MA, US
Geertruida M. Veldman - Sudbury MA, US
Amy Venturini - Lexington MA, US
Angela Widom - Acton MA, US
Stuart Friedrich - Melrose MA, US
Nicholas W. Warne - Andover MA, US
Angela Myles - Andover MA, US
John Gawain Elvin - Cambridge, GB
Alexander Robert Duncan - Little Shelford, GB
Elaine Joy Derbyshire - Royston, GB
Sara Carmen - Cambridge, GB
Thor Las Holtet - Royston, GB
Sarah Leila Du Fou - Hitchen, GB
Stephen Smith - Ely, GB
Assignee:
Abbott GmbH & Co. KG - Wiesbaden
International Classification:
C07K016/18
C07K016/24
C12P021/08
US Classification:
5303873, 5303871, 5303879, 53038815, 53038824, 5303892, 530351
Abstract:
Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the invention are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e. g. , in a human subject suffering from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention.

Humanized Immunoglobulin Reactive With B7-2 And Methods Of Treatment Therewith

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US Patent:
6972125, Dec 6, 2005
Filed:
Feb 12, 1999
Appl. No.:
09/249011
Inventors:
Man Sung Co - Cupertino CA, US
Maximiliano Vasquez - Palo Alto CA, US
Beatriz Carreno - Acton MA, US
Abbie Cheryl Celniker - Newton MA, US
Mary Collins - Natick MA, US
Samuel Goldman - Acton MA, US
Gary S. Gray - Brookline MA, US
Andrea Knight - Hampton NH, US
Denise O'Hara - Reading MA, US
Bonita Rup - Reading MA, US
Geertruida M. Veldman - Sudbury MA, US
Assignee:
Genetics Institute, LLC - Cambridge MA
International Classification:
A61K039/395
C07K016/28
C12N015/13
US Classification:
4241531, 4241301, 4241331, 4241411, 4241431, 4241441, 4241731, 435 696, 4352523, 4353201, 435326, 435328, 435332, 435334, 435343, 4353431, 435346, 435440, 435455, 5303871, 5303873, 5303881, 5303882, 53038822, 5303887, 53038873, 536 231, 536 234, 536 235, 536 2353
Abstract:
The invention relates to a humanized anti-B7-2 antibody that comprises a variable region of nonhuman origin and at least a portion of an immunoglobulin of human origin. The invention also pertains to methods of treatment for various autoimmune diseases, transplant rejection, inflammatory disorders and infectious diseases by administering humanized anti-B7-2 and/or anti-B7-1 antibodies.

Method Of Transplanting Cells By Contacting Donor Cells With B7-1-And B7-2-Specific Immunoglobulins

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US Patent:
6984383, Jan 10, 2006
Filed:
Jul 27, 2000
Appl. No.:
09/626731
Inventors:
Man Sung Co - Cupertino CA, US
Maximiliano Vasquez - Palo Alto CA, US
Beatriz Carreno - Acton MA, US
Abbie Cheryl Celniker - Newton MA, US
Mary Collins - Natick MA, US
Samuel Goldman - Acton MA, US
Gary S. Gray - Brookline MA, US
Andrea Knight - Hampton NH, US
Denise O'Hara - Reading MA, US
Bonita Rup - Reading MA, US
Geertruida M. Veldman - Sudbury MA, US
Assignee:
Genetics Institute, LLC - Cambridge MA
International Classification:
A61K 39/395
A61K 35/26
A61K 35/28
C07K 16/28
US Classification:
4241531, 4241301, 4241331, 4241401, 4241411, 4241431, 4241441, 4241731, 424 937, 424 9371, 424577, 424578, 5303871, 5303873, 5303881, 5303882, 53038822, 5303887, 53038873
Abstract:
The invention relates to a humanized anti-B7-2 antibody that comprises a variable region of nonhuman origin and at least a portion of an immunoglobulin of human origin. The invention also pertains to methods of treatment for various autoimmune diseases, transplant rejection, inflammatory disorders and infectious diseases by administering humanized anti-B7-2 and/or anti-B7-1 antibodies.

Antibody Inhibitors Of Gdf-8 And Uses Thereof

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US Patent:
7320789, Jan 22, 2008
Filed:
Sep 25, 2002
Appl. No.:
10/253532
Inventors:
Neil M. Wolfman - Dover MA, US
Denise O'Hara - Reading MA, US
Monique V. Davies - Harpswell MA, US
Geertruida M. Veldman - Sudbury MA, US
Kristie Grove Bridges - Maynard MA, US
Lisa-Anne Whittemore - East Walpole MA, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 39/00
C07K 16/00
C12N 5/16
US Classification:
4241301, 4241331, 4241351, 4241411, 435326, 5303871, 5303881
Abstract:
The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), including antibody fragments, which inhibit GDF-8 activity in vitro and in vivo. The disclosure also provides methods for diagnosing, preventing, or treating degenerative disorders of muscle, bone, or insulin metabolism.

Human Antibodies That Bind Human Il-12

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US Patent:
7504485, Mar 17, 2009
Filed:
Jul 1, 2004
Appl. No.:
10/884830
Inventors:
Jochen G. Salfeld - North Grafton MA, US
Michael Roguska - Ashland MA, US
Michael Paskind - Sterling MA, US
Subhashis Banerjee - Shrewsbury MA, US
Daniel Edward Tracey - Harvard MA, US
Michael White - Framingham MA, US
Zehra Kaymakcalan - Westborough MA, US
Boris Labkovsky - Marlborough MA, US
Paul Sakorafas - Newton MA, US
Geertruida M. Veldman - Sudbury MA, US
Amy Venturini - Lexington MA, US
Angela Widom - Acton MA, US
Stuart Friedrich - Cary NC, US
Nicholas W. Warne - Andover MA, US
Angela Myles - Andover MA, US
John Gawain Elvin - Cambridge, GB
Alexander Robert Duncan - Cambridge, GB
Elaine J. Derbyshire - Royston, GB
Sara Carmen - Cambridge, GB
Stephen Smith - Ely, GB
Thor Las Holtet - Royston, GB
Sarah Leila Du Fou - Hitchen, GB
Assignee:
Abbott GmbH & Co., KG - Wiesbaden
International Classification:
C07K 16/24
A61K 39/395
US Classification:
53038823, 4241451
Abstract:
Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the invention are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e. g. , in a human subject suffering from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention.

Methods For Modulation Of Immune Responses Using Humanized Immunoglobulins Reactive With B7-1 Molecules

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US Patent:
7531175, May 12, 2009
Filed:
Nov 12, 2004
Appl. No.:
10/986089
Inventors:
Man Sung Co - Cupertino CA, US
Maximiliano Vasquez - Palo Alto CA, US
Beatriz Carreno - Acton MA, US
Abbie Cheryl Celniker - Newton MA, US
Mary Collins - Natick MA, US
Samuel Goldman - Acton MA, US
Gary S. Gray - Brookline MA, US
Andrea Knight - Hampton NH, US
Denise O'Hara - Reading MA, US
Bonita Rup - Reading MA, US
Geertruida M. Veldman - Sudbury MA, US
Assignee:
Genetics Institute LLC - Madison NJ
International Classification:
A61K 39/395
C07K 16/28
US Classification:
4241531, 4241301, 4241331, 4241401, 4241411, 4241431, 4241731, 5303871, 5303873, 5303881, 5303882, 53038822, 5303887, 53038873
Abstract:
The invention relates to humanized anti-B7-2 and anti-B7-1 antibodies, wherein each comprise a variable region of non-human origin and at least a portion of an immunoglobulin of human origin. The invention also pertains to methods of treatment for various autoimmune diseases, transplant rejection, inflammatory disorders and infectious diseases by administering humanized anti-B7-2 and/or anti-B7-1 antibodies.
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Geertruida M Veldman from Sudbury, MA, age ~71 Get Report