Gabriella Colucci Phones & Addresses
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8703 Glenwick Ln, La Jolla, CA 92037
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8724 Villa La Jolla Dr, La Jolla, CA 92037 (858) 638-1544
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8726 Villa La Jolla Dr, La Jolla, CA 92037
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San Diego, CA
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8724 Villa La Jolla Dr, La Jolla, CA 92037 (858) 692-2692
Work
Position:
Construction and Extraction Occupations
Education
Degree:
Bachelor's degree or higher
Publications
Us Patents
Non-Endogenous, Constitutively Activated Versions Of Plant G Protein-Coupled Receptor: Gcr1
View pageUS Patent:
20030073812, Apr 17, 2003
Filed:
Jun 5, 2002
Appl. No.:
10/164163
Inventors:
Gabriella Colucci - La Jolla CA, US
International Classification:
A01N025/00
C07K014/415
C07H021/04
C12P021/02
C12N005/04
C07K014/415
C07H021/04
C12P021/02
C12N005/04
US Classification:
530/350000, 504/116100, 536/023600, 435/069100, 435/320100, 435/419000
Abstract:
The invention relates to transmembrane receptors for which the endogenous ligand has not been identified, and specifically to a plant GPCR (“GCR1”) that has been altered to establish constitutive activity of the receptor. In some embodiments, the altered versions of GCR1 are used for the direct identification of candidate compounds as receptor agonists, inverse agonists or partial agonists for use in, for example and not limitation, herbicidal relevance; germination; growth elongation; seed dormancy; and fruit and vegetable ripening and development. In some embodiments, altered versions of GCR1 are used to modulate physiological processes in a plant. The invention further relates to plants comprising constitutively activated non-endogenous GPCRs.
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