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Frances R Lawyer

from Grand Prairie, TX
Age ~83

Frances Lawyer Phones & Addresses

  • 2901 Mayfield Rd, Grand Prairie, TX 75052 (972) 602-9420 (972) 606-6449
  • 2901 Mayfield Rd APT 5201, Grand Prairie, TX 75052 (972) 977-5159
  • Hayward, CA
  • Oakland, CA
  • San Leandro, CA

Work

Position: Administrative Support Occupations, Including Clerical Occupations

Education

Degree: Associate degree or higher

Emails

Publications

Us Patents

Recombinant Expression Vectors And Purification Methods For Thermus Thermophilus Dna Polymerase

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US Patent:
57892245, Aug 4, 1998
Filed:
Jun 2, 1995
Appl. No.:
8/459383
Inventors:
David H. Gelfand - Oakland CA
Frances C. Lawyer - Davis CA
Susanne Stoffel - El Cerrito CA
Assignee:
Roche Molecular Systems, Inc. - Branchburg NJ
International Classification:
C12N 912
US Classification:
435194
Abstract:
Recombinant DNA sequences encoding the DNA polymerase activity of Thermus thermophilus can be used to construct recombinant vectors and transformed host cells for production of the activity. T. thermophilus DNA polymerase is an. about. 94 kDa protein especially useful in the DNA amplification procedure known as the polymerase chain reaction.

Purified Thermostable Nucleic Acid Polymerase Enzyme From Thermotoga Maritima

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US Patent:
56248334, Apr 29, 1997
Filed:
Jun 7, 1995
Appl. No.:
8/475231
Inventors:
David H. Gelfand - Oakland CA
Frances C. Lawyer - Oakland CA
Susanne Stoffel - El Cerrito CA
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
C12N 912
US Classification:
435194
Abstract:
A purified thermostable enzyme is derived from the eubacterium Thermotoga maritima. The enzyme has a molecular weight as determined by gel electrophoresis of about 97 kilodaltons and DNA polymerase I activity. The enzyme can be produced from native or recombinant host cells and can be used with primers and nucleoside triphosphates in a temperature-cycling chain reaction where at least one nucleic acid sequence is amplified in quantity from an existing sequence.

Purified Thermostable Enzyme

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US Patent:
48898180, Dec 26, 1989
Filed:
Jun 17, 1987
Appl. No.:
7/063509
Inventors:
David H. Gelfand - Oakland CA
Susanne Stoffel - El Cerrito CA
Frances C. Lawyer - Oakland CA
Randall K. Saiki - Richmond CA
Assignee:
Cetus Corporation - Emeryville CA
International Classification:
C12N 900
US Classification:
435194
Abstract:
A purified thermostable enzyme is obtained that has unique characteristics. Preferably the enzyme is isolated from the Thermus aquaticus species and has a molecular weight of about 86,000-90,000 daltons. The thermostable enzyme may be native or recombinant and may be used in a temperature-cycling chain reaction wherein at least one nucleic acid sequence is amplified in quantity from an existing sequence with the aid of selected primers and nucleotide triphosphates. The enzyme is preferably stored in a buffer of non-ionic detergents that lends stability to the enzyme.

Sv40 Early And Rsv Promoters Useful In Saccharomyces Expression

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US Patent:
48700134, Sep 26, 1989
Filed:
May 18, 1988
Appl. No.:
7/196789
Inventors:
David H. Gelfand - Oakland CA
Frances C. Lawyer - Oakland CA
Susanne Stoffel - El Cerrito CA
Assignee:
Cetus Corporation - Emeryville CA
International Classification:
C12P 2100
C12N 1500
C12N 500
US Classification:
435 68
Abstract:
Expression vectors containing coding sequences under the control of SV40 early and RSV promoters are disclosed as useful in producing proteins in saccharomyces yeasts. Construction of such vectors, and their use in yeast transformations are described.

Recombinant Diphtheria Toxin Fragments

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US Patent:
48309621, May 16, 1989
Filed:
Feb 9, 1984
Appl. No.:
6/578122
Inventors:
David H. Gelfand - Oakland CA
Lawrence I. Greenfield - Albany CA
Frances C. Lawyer - Oakland CA
Assignee:
Cetus Corporation - Emeryville CA
International Classification:
C12P 2100
C12N 1500
C12N 120
US Classification:
435 68
Abstract:
Recombinant vectors which are effective in expressing DNA sequences encoding specific fragments of diphtheria toxins at high levels in recombinant host cells are disclosed. Both a fragment consisting of the enzymatically active A chain of diphtheria toxin and a fragment consisting of both the A portion and a B portion partial sequence are constructed by use of this recombinant vector.

Mutated Thermostable Nucleic Acid Polymerase Enzyme From Thermotoga Maritima

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US Patent:
54200296, May 30, 1995
Filed:
Feb 3, 1993
Appl. No.:
7/971819
Inventors:
David H. Gelfand - Oakland CA
Frances C. Lawyer - Oakland CA
Susanne Stoffel - El Cerrito CA
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
C12N 1500
C12N 912
US Classification:
435194
Abstract:
A purified thermostable enzyme is derived from the eubacterium Thermotoga maritima. The enzyme has a molecular weight as determined by gel electrophoresis of about 97 kilodaltons and DNA polymerase I activity. The enzyme can be produced from native or recombinant host cells and can be used with primers and nucleoside triphosphates in a temperature-cycling chain reaction where at least one nucleic acid sequence is amplified in quantity from an existing sequence.

Recombinant Expression Vectors And Purification Methods For Thermus Thermophilus Dna Polymerase

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US Patent:
56187114, Apr 8, 1997
Filed:
Feb 6, 1995
Appl. No.:
8/384490
Inventors:
David H. Gelfand - Oakland CA
Frances C. Lawyer - Davis CA
Susanne Stoffel - El Cerrito CA
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
C12N 1554
C12N 912
US Classification:
435194
Abstract:
Recombinant DNA sequences encoding the DNA polymerase activity of Thermus thermophilus can be used to construct recombinant vectors and transformed host cells for production of the activity. T. thermophilus DNA polymerase is an. about. 94 kDa protein especially useful in the DNA amplification procedure known as the polymerase chain reaction.

Dna Encoding A Thermostable Nucleic Acid Polymerase Enzyme From Thermotoga Maritima

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US Patent:
53745531, Dec 20, 1994
Filed:
Aug 13, 1990
Appl. No.:
7/567244
Inventors:
David H. Gelfand - Oakland CA
Frances C. Lawyer - Oakland CA
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
C12N 912
C12N 1500
C12N 120
US Classification:
4352523
Abstract:
A purified thermostable enzyme is derived from the eubacterium Thermotoga maritima. The enzyme has a molecular weight of about 97 kilodaltons and DNA polymerase I activity. The enzyme can be produced from native or recombinant host cells and can be used with primers and nucleoside triphosphates in a temperaturecycling chain reaction where at least one nucleic acid sequence is amplified in quantity from an existing sequence.
Frances R Lawyer from Grand Prairie, TX, age ~83 Get Report