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Ernst Rinderknecht Phones & Addresses

  • 812 Bauer Dr, San Carlos, CA 94070 (650) 591-9387
  • Palo Alto, CA
  • San Mateo, CA
  • 812 Bauer Dr, San Carlos, CA 94070 (650) 303-0680

Work

Position: Professional/Technical

Education

Degree: Graduate or professional degree

Resumes

Resumes

Ernst Rinderknecht Photo 1

Principal Fellow

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Location:
812 Bauer Dr, San Carlos, CA 94070
Industry:
Pharmaceuticals
Work:
Novartis
Principal Fellow
Skills:
Biotechnology
Restructuring
Financial Advisory
Advisory
Ernst Rinderknecht Photo 2

Ernst Rinderknecht

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Business Records

Name / Title
Company / Classification
Phones & Addresses
Ernst Rinderknecht
Vice President Process Science And Manufacturing
CORTHERA, INC
Pharmaceutical Research · Research and Development in the Social Sciences and Humaniti
150 Industrial Rd, San Carlos, CA 94070
1660 S Amphlett Blvd, San Mateo, CA 94402
(650) 235-3577

Publications

Us Patents

Recombiniant Gamma Interferons Having Enhanced Stability And Methods Therefor

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US Patent:
6497871, Dec 24, 2002
Filed:
Jun 2, 1995
Appl. No.:
08/460539
Inventors:
Patrick W. Gray - San Francisco CA
Ernst H. Rinderknecht - San Carlos CA
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
A61K 3821
US Classification:
424 855, 514 12, 530351, 435 6951, 536 2352
Abstract:
The present invention relates to novel, stable recombinant gamma interferons exhibiting in greater or less degree the antiviral and antiproliferative activity in humans and pH 2 labile properties characteristic of native human gamma interferon. The amino acid sequence of such an interferon comprises, from the N-terminus: wherein X is a methionine residue or hydrogen and Y is a glutamine residue, or, where X is hydrogen, Y is either a glutamine or a pyroglutamate residue.

Antibody Purification

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US Patent:
7038017, May 2, 2006
Filed:
Jan 4, 2001
Appl. No.:
09/754998
Inventors:
Ernst H. Rinderknecht - San Carlos CA, US
Gerardo A. Zapata - Foster City CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C07K 16/00
C12P 21/08
US Classification:
5303871, 5303873, 5303877, 53038822, 5303888, 53038885
Abstract:
A process for purifying an antibody is provided. In this process, a mixture containing the antibody and a contaminant is subjected to low pH hydrophobic interaction chromatography (LPHIC) at low salt concentration. The antibody is eluted from the column in the fraction which does not bind thereto. This process can be preceded and followed by other purification steps.

Antibody Compositions

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US Patent:
8012754, Sep 6, 2011
Filed:
Jul 1, 2005
Appl. No.:
11/173564
Inventors:
Ernst H. Rinderknecht - San Carlos CA, US
Gerardo A. Zapata - Foster City CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C12N 15/07
US Classification:
435451, 435455
Abstract:
A process for purifying an antibody is provided. In this process, a mixture containing the antibody and a contaminant is subjected to low pH hydrophobic interaction chromatography (LPHIC) at low salt concentration. The antibody is eluted from the column in the fraction which does not bind thereto. This process can be preceded and followed by other purification steps.

Recombinant Gamma Interferons Having Enhanced Stability And Methods Therefor

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US Patent:
55741371, Nov 12, 1996
Filed:
Sep 23, 1994
Appl. No.:
8/311765
Inventors:
Patrick W. Gray - San Francisco CA
Ernst H. Rinderknecht - San Carlos CA
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C07K 1457
US Classification:
530351
Abstract:
The present invention relates to novel, stable recombinant gamma interferons exhibiting in greater or less degree the antiviral and antiproliferative activity in humans and pH 2 labile properties characteristic of native human gamma interferon. The amino acid sequence of such an interferon comprises, from the N terminus: ##STR1## wherein X is a methionine residue or hydrogen and Y is a glutamine residue or, where X is hydrogen, Y is either a glutamine or a pyroglutamate residue.

Low Ph Hydrophobic Interaction Chromatography For Antibody Purification

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US Patent:
56418701, Jun 24, 1997
Filed:
Apr 20, 1995
Appl. No.:
8/425763
Inventors:
Ernst H. Rinderknecht - San Carlos CA
Gerardo A. Zapata - Foster City CA
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C07K 116
US Classification:
530417
Abstract:
A process for purifying an antibody is provided. In this process, a mixture containing the antibody and contaminant is subjected to low pH hydrophobic interaction chromatography (LPHIC) optionally at low salt concentration. The antibody is eluted from the column in the fraction which does not bind thereto. This process can be preceded and followed by other purification steps.

Recombinant Methods Of Making Gamma Interferon Compositions

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US Patent:
55958885, Jan 21, 1997
Filed:
Mar 24, 1994
Appl. No.:
8/221542
Inventors:
Patrick W. Gray - San Francisco CA
Ernst H. Rinderknecht - San Carlos CA
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C12N 1523
C12N 121
US Classification:
435 6951
Abstract:
Provided are methods for the production of mixtures of interferon (IFN)-. gamma. polypeptides. The methods employ a single species of IFN-. sub. gamma. DNA having codons for Met-Gln and for residues 2-143 of the mature human IFN-. sub. gamma. amino acid sequence. Expression of such DNA in a suitable recombinant host cell affords a mixture of polypeptides having N-terminal Met-Gln, H-Gln, or H-pyroglutamate residues and C-termini at Arg. sup. 139, Ser. sup. 142, or Gln. sup. 143 of the mature IFN-. sub. gamma. sequence. The polypeptides so produced exhibit the antiviral and antiproliferative activities as well as the acid lability characteristic of native human IFN-. sub. gamma.

Process For Producing Relaxin

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US Patent:
57598070, Jun 2, 1998
Filed:
May 22, 1995
Appl. No.:
8/443568
Inventors:
Tim Breece - San Francisco CA
Kirk Hayenga - San Mateo CA
Ernst Rinderknecht - San Carlos CA
Richard Vandlen - Hillsborough CA
Daniel Yansura - Pacifica CA
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C12N 1512
C12N 1563
C12N 510
C07K 1464
US Classification:
435 691
Abstract:
A process for the prokaryotic production of relaxin from non-naturally occurring forms of prorelaxin is provided. Also provided are non-naturally occurring forms of prorelaxin.

Recombinant Gamma Interferons Having Enhanced Stability And Methods Therefor

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US Patent:
56909250, Nov 25, 1997
Filed:
Mar 22, 1994
Appl. No.:
8/216511
Inventors:
Patrick W. Gray - San Francisco CA
Ernst H. Rinderknecht - San Carlos CA
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
A61K 3821
C07K 1457
US Classification:
424 855
Abstract:
The present invention relates to novel, stable recombinant gamma interferons exhibiting in greater or less degree the antiviral and antiproliferative activity in humans and pH 2 labile properties characteristic of native human gamma interferon. The amino acid sequence of such an interferon comprises, from the N-terminus: ##STR1## wherein X is a methionine residue or hydrogen and Y is a glutamine residue or, where X is hydrogen, Y is either a glutamine or a pyroglutamate residue.
Ernst H Rinderknecht from San Carlos, CA, age ~77 Get Report