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Eric Deziel Phones & Addresses

  • Boston, MA
  • 124 Summer St, Somerville, MA 02143 (617) 764-1826

Publications

Us Patents

Methods For Identifying Candidate Compounds For Treating, Reducing, Or Preventing Pathogenic Infections

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US Patent:
20070292851, Dec 20, 2007
Filed:
Jan 21, 2005
Appl. No.:
10/586403
Inventors:
Laurence Rahme - Brookline MA, US
Eric Deziel - Somerville MA, US
Francois Lepine - Longueuil, CA
Ronald Tompkins - Boston MA, US
Gaoping Xiao - Malden MA, US
International Classification:
C12Q 1/68
C12Q 1/18
US Classification:
435006000, 435032000
Abstract:
Disclosed are methods for identifying candidate compounds for treating, reducing, or preventing a pathogenic infection, the methods including: (a) contacting a pathogenic cell with a candidate compound; and (b) measuring the production of a molecule selected from the group consisting of an 4-hydroxy-2-alkylquinoline (HAQ) molecule, 4-hydroxy-2-heptylquinoline (HHQ) molecule, or a derivative or precursor thereof in the cell, a candidate compound that reduces the production relative to production of the molecule by a cell not contacted with the candidate compound, identifying a candidate compound useful for treating, reducing, or preventing a pathogenic infection.

Methods For The Prevention Or Treatment Of Bacterial And Fungal Infections

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US Patent:
20100184804, Jul 22, 2010
Filed:
Nov 20, 2009
Appl. No.:
12/623307
Inventors:
Laurence G. Rahme - Brookline MA, US
Hui Cao - Natick MA, US
Francois Lepine - Montreal, CA
Eric Deziel - Somerville MA, US
Ronald G. Tompkins - Boston MA, US
International Classification:
A61K 31/47
A61K 31/335
C12Q 1/02
A61P 31/04
US Classification:
514312, 514449, 435 29
Abstract:
The present invention features improved methods for treating, stabilizing, or preventing a bacterial or a fungal infection in a plant or an animal, such as a mammal. In particular, these methods involve the use of a compound, that is controlled by MvfR, and that affects the expression of an MvfR protein or that promotes its modification or inactivation, or a compound produced by strain PA14, but not by containing an mvfR mutation, in late stationary phase cultures.

Methods For The Prevention Or Treament Of Bacterial And Fungal Infections

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US Patent:
20050119302, Jun 2, 2005
Filed:
Oct 30, 2002
Appl. No.:
10/493989
Inventors:
Laurence Rahme - Brookline MA, US
Hui Cao - Natick MA, US
Francois Lepine - Quebec Montreal, CA
Eric Deziel - Somerville MA, US
Ronald Tompkins - Boston MA, US
International Classification:
A61K031/47
US Classification:
514312000
Abstract:
The present invention features improved methods for treating, stabilizing, or preventing a bacterial or a fungal infection in a plant or an animal, such as a mammal. In particular, these methods involve the use of a compound, that is controlled by MvfR, and that affects the expression of an MvfR protein or that promotes its modification or inactivation, or a compound produced by strain PA14, but not by containing an mvfR mutation, in late stationary phase culture.
Eric Deziel from Boston, MA, age ~54 Get Report