Search

Elena Ivanova Phones & Addresses

  • Canton, MA
  • Braintree, MA
  • Des Plaines, IL
  • Somerville, MA
  • Itasca, IL
  • Weymouth, MA

Publications

Us Patents

Methods For Evaluating Tumor Cell Spheroids Using 3D Microfluidic Cell Culture Device

View page
US Patent:
20210087635, Mar 25, 2021
Filed:
Mar 30, 2018
Appl. No.:
16/498907
Inventors:
- Boston MA, US
David Barbie - Andover MA, US
Cloud P. Paweletz - Boston MA, US
Elena Ivanova - Brookline MA, US
Amir Aref - Chestnut Hill MA, US
Assignee:
Dana-Farber Cancer Institute, Inc. - Boston MA
International Classification:
C12Q 1/6886
C12M 3/06
C12N 1/04
C12N 9/64
C12Q 1/6869
C12Q 1/6881
Abstract:
Provided herein are methods for evaluating tumor cell spheroids in a three-dimensional microfluidic device by determining changes in the relative levels of live cells and dead cells in aliquots cultured under different conditions. Methods described herein allow ex vivo recapitulation of the tumor microenvironment such that the in vivo effectiveness of a test compound in treating tumor tissue may be predicted.

Methods For Evaluating Tumor Cell Spheroids Using 3D Microfluidic Cell Culture Device

View page
US Patent:
20190112666, Apr 18, 2019
Filed:
Aug 17, 2018
Appl. No.:
15/999230
Inventors:
- Boston MA, US
Russell W. Jenkins - Boston MA, US
Cloud P. Paweletz - Boston MA, US
Elena Ivanova - Brookline MA, US
Amir Aref - Malden MA, US
Assignee:
Dana-Farber Cancer Institute, Inc. - Boston MA
International Classification:
C12Q 1/6886
C12N 9/64
C12N 1/04
C12Q 1/6869
C12Q 1/6881
Abstract:
Provided herein are methods for evaluating tumor cell spheroids in a three-dimensional microfluidic device by determining changes in the relative levels of live cells and dead cells in aliquots cultured under different conditions. Methods described herein allow ex vivo recapitulation of the tumor microenvironment such that the in vivo effectiveness of a test compound in treating tumor tissue may be predicted.
Elena D Ivanova from Canton, MA, age ~39 Get Report