Inventors:
Richard Gelbart - San Diego CA, US
Don L. Powrie - San Diego CA, US
Paul David Swanson - Santee CA, US
Assignee:
Nanogen, Inc. - San Diego CA
International Classification:
G01N 27/27
G01N 27/26
G01N 27/327
G01N 27/453
G01N 15/06
US Classification:
204406, 422 50, 422 61, 422 681, 422 81, 422 8201, 422 8202, 436 43, 436 63, 436149, 436150, 436151, 204193, 204400, 20440301, 20440303, 20440313, 204407, 204409, 204411, 204412
Abstract:
The present invention is directed to devices and methods for carrying out and/or monitoring biological reactions in response to electrical stimuli. A programmable multiplexed active biologic array includes an array of electrodes coupled to sample-and-hold circuits. The programmable multiplexed active biologic array includes a digital interface that allows external control of the array using an external processor. The circuit may monitor, digitally control, and deliver electrical stimuli to the electrodes individually or in selected groups.