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Domenico Accili

from New York, NY
Age ~66
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Also known as:
Domenico Accilio, Accili Domenico
Phone and address:
80 Chambers St APT 15A, New York, NY 10007
(917) 992-4239
Related to:
Najjar AntoineMonique HurdleS Najjar, 68Sonia M Najjar, 68Guilda M Najjar, 48Elias M Najjar, 58Antoine M Najjar, 63Maya M Najjar, 37Mona S NajjarD R NajjarAntonia M Najjar, 63Michael M Najjar, 40George M NajjarGuilda M Najjar, 53Mireille M NajjarAnthony NajjarVera G Najjar, 54Maha M Hurdle, 65Nina N Najjar, 62Marwan M Najjar, 69George M Najjar, 60
Connected to:
Junette Accime, 55Michael P Accinno, 37Alberto M Accion, 57Jennifer L Accisano, 34Albotte Accius, 59Jessica Accius, 37David K Acco, 54Colby Accola, 42Jason E Accola, 42Jeremiah Accola, 31

Domenico Accili Phones & Addresses

  • 80 Chambers St APT 15A, New York, NY 10007 (917) 992-4239
  • 541 113Th St, New York, NY 10025
  • 80 Chambers St, New York, NY 10007
  • Maumee, OH
  • Rockville, MD
  • Toledo, OH

Work

Company: NEW YORK PRESBYTERIAN HOSPITAL Address: 622 W 168Th St, New York, NY 10032 Phones: (212) 746-3600 (212) 342-2717

Education

School / High School: University Cattolica Del Sacro Cuore

Languages

English

Specialities

Endocrinology, Diabetes & Metabolism • Endocrinology

Professional Records

Medicine Doctors

Domenico Accili Photo 1

Dr. Domenico Accili, New York NY - MD (Doctor of Medicine)

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Specialties:
Endocrinology, Diabetes & Metabolism
Endocrinology
Address:
1150 Saint Nicholas Ave Suite 238, New York, NY 10032
(212) 304-7391 (Phone)

NEW YORK PRESBYTERIAN HOSPITAL
622 W 168Th St, New York, NY 10032
(212) 746-3600 (Phone), (212) 342-2717 (Fax)

630 W 168Th St Suite 4, New York, NY 10032
(212) 851-5332 (Phone), (212) 851-5331 (Fax)

NAOMI BERRIE DIABETES CENTER
1150 Saint Nicholas Ave Suite 2Nd, New York, NY 10032
(212) 851-5494 (Phone), (212) 851-5493 (Fax)
Languages:
English
Hospitals:
1150 Saint Nicholas Ave Suite 238, New York, NY 10032

630 W 168Th St Suite 4, New York, NY 10032

NEW YORK PRESBYTERIAN HOSPITAL
622 W 168Th St, New York, NY 10032

NAOMI BERRIE DIABETES CENTER
1150 Saint Nicholas Ave Suite 2Nd, New York, NY 10032

NewYork-Presbyterian Hospital/Columbia University Medical Center
630 West 168Th Street, New York, NY 10032
Education:
Medical School
University Cattolica Del Sacro Cuore
Domenico Accili Photo 2

Domenico Md Accili, New York NY

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Specialties:
Endocrinologist
Address:
630 W 168Th St, New York, NY 10032
1150 Saint Nicholas Ave, New York, NY 10032

Business Records

Name / Title
Company / Classification
Phones & Addresses
Domenico Accili
Domenico Accili MD
Internist
1150 Saint Nicholas Ave, New York, NY 10032
(212) 851-5332
Domenico Accili
Medical Doctor
The Trustees of Columbia University In The City of New York
College/University
1150 Saint Nicholas Ave, New York, NY 10032
301 Heffernan Dr, New Haven, CT 06516

Publications

Us Patents

Methods For Producing Enteroendocrine Cells That Make And Secrete Insulin

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US Patent:
20130216554, Aug 22, 2013
Filed:
May 12, 2011
Appl. No.:
13/697792
Inventors:
Chutima Talchai - New York NY, US
Domenico Accili - New York NY, US
International Classification:
A61K 39/395
A61K 31/7088
US Classification:
4241721, 514 44 A, 5303898, 536 245, 435375, 506 10, 435 79
Abstract:
Methods are described for producing enteroendocrine cells that make and secrete insulin in a mammal by blocking the expression or biological activity of one or more Foxo proteins or biologically active fragments or variants thereof.

Generation Of Pancreatic Endocrine Cells From Primary Duct Cell Cultures And Methods Of Use For Treatment Of Diabetes

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US Patent:
20080260700, Oct 23, 2008
Filed:
Feb 26, 2008
Appl. No.:
12/037401
Inventors:
Domenico ACCILI - New York NY, US
Tadahiro Kitamura - Fort Lee NJ, US
Assignee:
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK - New York NY
International Classification:
A61K 35/12
C12N 5/00
A61P 3/10
C12N 5/08
US Classification:
424 937, 435325, 435366
Abstract:
The invention is directed to spontaneously immortalized pancreatic duct cells and methods for generating pancreatic endocrine cells from spontaneously immortalized pancreatic duct cells that express the transcription factors Pdx1 and FoxO1. The invention also provides for methods for treating beta cell failure, the method comprising administering to a subject an effective amount of spontaneously immortalized pancreatic duct cells expressing a mutated version FoxO1.

Selective Foxo Inhibitors For Treatment Of Diabetes And Other Disorders Related To Impaired Pancreatic Function

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US Patent:
20220185797, Jun 16, 2022
Filed:
Mar 25, 2020
Appl. No.:
17/598695
Inventors:
- New York NY, US
- Weston MA, US
Donald W. LANDRY - New York NY, US
Robert J. DEVITA - Westfield NJ, US
Hua V. LIN - Zionsville IN, US
Yunkyoung LEE - New York NY, US
Domenico ACCILI - New York NY, US
Sandro BELVEDERE - Weston MA, US
International Classification:
C07D 403/04
A61K 31/713
A61K 31/4184
A61K 31/496
C07D 401/14
A61K 31/454
C07D 405/14
C07D 413/14
A61K 31/423
A61K 31/4709
A61K 31/4439
C07D 471/04
A61K 31/437
Abstract:
Various embodiments relate to a compound (represented by Formula I) or a pharmaceutically acceptable salt or tautomer thereof. The compound may selectively inhibit a Forkhead Box O1 (FOXO1) transcription factor. Various embodiments relate to methods comprising administering to a mammal having a disease or disorder associated with impaired pancreatic endocrine function, a therapeutically effective amount of the compound or a pharmaceutically acceptable salt or tautomer thereof. Various embodiments relate to methods for producing enteroendocrine cells that make and secrete insulin in a mammal, comprising administering to the mammal an effective amount of the compound or a pharmaceutically acceptable salt or tautomer thereof.

Methods For Producing Enteroendocrine Cells That Make And Secrete Insulin

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US Patent:
20200095585, Mar 26, 2020
Filed:
Dec 5, 2019
Appl. No.:
16/704830
Inventors:
- New York NY, US
Domenico Accili - New York NY, US
International Classification:
C12N 15/113
G01N 33/50
A61K 31/7088
A61K 39/395
C12N 5/071
Abstract:
Methods are described for producing enteroendocrine cells that make and secrete insulin in a mammal by blocking the expression or biological activity of one or more forkhead box O (Foxo) proteins or biologically active fragments or variants thereof.

Genetically Modified Ips Cells That Carry A Marker To Report Expression Of Neurogenin3, Tph2, Foxo1 And/Or Insulin Genes

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US Patent:
20180171302, Jun 21, 2018
Filed:
Jun 27, 2016
Appl. No.:
15/739443
Inventors:
Domenico Accili - New York NY, US
International Classification:
C12N 5/074
C12Q 1/6897
Abstract:
Provided herein are insulin-negative cells that have been genetically modified to report expression of one or more target genes. Exemplified are reporter cell lines that provide a readout of Ngn3, Foxo1 or Tph2 expression. Reporter cells are used to screen for agents that affect expression of one or more of these genes to identify agents capable of converting gut progenitor cells to insulin-positive cells.

Methods For Producing Enteroendocrine Cells That Make And Secrete Insulin

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US Patent:
20170044532, Feb 16, 2017
Filed:
Aug 19, 2016
Appl. No.:
15/241674
Inventors:
- New York NY, US
Domenico Accili - New York NY, US
International Classification:
C12N 15/113
C12N 5/071
G01N 33/50
Abstract:
Methods are described for producing enteroendocrine cells that make and secrete insulin in a mammal by blocking the expression or biological activity of one or more Foxo proteins or biologically active fragments or variants thereof.

Isbn (Books And Publications)

Genetic Manipulation of Receptor Expression and Function

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Author

Domenico Accili

ISBN #

0471350575

Control profile
Domenico Accili from New York, NY, age ~66 Get Report