Inventors:
Warren J. Strittmatter - Durham NC
Allen D. Roses - Durham NC
David Huang - Durham NC
Dmitry Y. Goldgaber - Setauket NY
Assignee:
Duke University - Durham NC
International Classification:
G01N 3353
G01N 33543
G01N 33563
Abstract:
The present invention relates to the finding that antibodies bind to the. beta. -amyloid peptide, and that. beta. -amyloid peptide binds the hinge region of the immunoglobulin heavy chain, thereby preserving the ability of the immunoglobulin to bind antigen. Methods for binding compounds such as detectable groups to. beta. -amyloid peptide are accordingly presented.